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Volume 2008
Issue 2
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Molbank, Volume 2008, Issue 2 (August 2008) – 8 articles

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172 KiB  
Short Note
Synthesis, Characterization and Antileucemic Activity of 7-Hydroxy-8-acetylcoumarin Benzoylhydrazone
by Antigoni Kotali, Ioannis S. Lafazanis, Athanassios Papageorgiou, Eleni Chrysogelou, Theodoros Lialiaris and Zacharias Sinakos
Molbank 2008, 2008(2), M574; https://doi.org/10.3390/M574 - 24 Aug 2008
Cited by 3 | Viewed by 3186
Abstract
As part of a research programme targeting novel molecules derived from nitrogen derivatives of o-hydroxyaryl ketones [1] we synthesised 7-hydroxy-8-acetylcoumarin benzoylhydrazone.[...] Full article
198 KiB  
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3-(1-Phenyl-1H-pyrazol-4-yl)-1,2-benzisoxazole 2-oxide
by Antigoni Kotali
Molbank 2008, 2008(2), M573; https://doi.org/10.3390/M573 - 24 Aug 2008
Cited by 4 | Viewed by 2897
Abstract
It is well known that both isoxazole ring as well as pyrazole ring possess various biological activities and they both show interesting antimicrobial activity [1,2,3].[...] Full article
203 KiB  
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9-Methyl-2H-chromeno[8,7-d]isoxazol-2-one N-oxide
by Antigoni Kotali, Ioannis S. Lafazanis and Philip A. Harris
Molbank 2008, 2008(2), M572; https://doi.org/10.3390/M572 - 24 Aug 2008
Cited by 4 | Viewed by 3417
Abstract
As part of a research programme targeting novel molecules derived from nitrogen derivatives of o-hydroxyaryl ketones [1] we synthesised 7-hydroxy-8-acetylcoumarin oxime and we subsequently oxidized it with lead tetraacetate (LTA) as well as with diacetoxy iodobenzene (DIB).[...] Full article
210 KiB  
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7-Hydroxy-8-acetylcoumarin N-1-(Carboxymethyl)pyridinium Chloride Hydrazone
by Antigoni Kotali, Ioannis S. Lafazanis and Philip A. Harris
Molbank 2008, 2008(2), M571; https://doi.org/10.3390/M571 - 24 Aug 2008
Cited by 1 | Viewed by 3232 | Correction
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148 KiB  
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7-Hydroxy-8-acetylcoumarin N-Phenylsulfonylhydrazone
by Antigoni Kotali, Ioannis S. Lafazanis and Philip A. Harris
Molbank 2008, 2008(2), M570; https://doi.org/10.3390/M570 - 24 Aug 2008
Viewed by 3098
Abstract
As part of a research programme targeting novel molecules derived from o-hydroxyaryl ketone hydrazones[1] we synthesised 7-hydroxy-8-acetylcoumarin phenylsulfonylhydrazone.[...] Full article
207 KiB  
Short Note
Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol)
by Gernot A. Eller and Wolfgang Holzer
Molbank 2008, 2008(2), M569; https://doi.org/10.3390/M569 - 22 Aug 2008
Cited by 1 | Viewed by 4393
Abstract
Methyl (2E)-3-methoxyacrylate and excess methylhydrazine yield crude 1- methyl-2-pyrazolin-5-one which is reacted with cyclohexanone to obtain the title compound in 86% yield. Detailed spectroscopic data (1H NMR, 13C NMR, 15N NMR, and MS) are presented. Full article
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295 KiB  
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Synthesis of 2-Fluoromethyl-7-methylnaphthalene
by Jane Bogdanov and Przemyslaw Maslak
Molbank 2008, 2008(2), M568; https://doi.org/10.3390/M568 - 22 Aug 2008
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n/a Full article
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Figure 1

176 KiB  
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N-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl (N-Dde) Lipoamino Acids
by Benjamin P. Ross, Robert A. Falconer and Istvan Thot
Molbank 2008, 2008(2), M566; https://doi.org/10.3390/M566 - 15 Aug 2008
Cited by 20 | Viewed by 5539
Abstract
The conjugation of a drug with one or more lipoamino acids (LAAs; 2-aminoalkanoic acids; e.g. 3) can impart upon the drug steric protection from enzymatic degradation, increased lipophilicity, increased passive membrane diffusion and therefore may improve drug bioavailability [1].[...] Full article
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