Measurement of Pulse Wave Signals and Blood Pressure by a Plastic Optical Fiber FBG Sensor

Round 1

Reviewer 1 Report

Comments (1). Line 29-30 Blood pressure is measured with low error, but the POFFBG APG correlation is distributed from 0.54 to 0.72, which is not as high as desired. What is the expected correlation? How to get a higher correlation? (2). Line 37-38 In recent years, the increase of medical expenses and lack of medical workers has become a social problem due to the aging society. The expression of this sentence seems to have some grammatical problems. There are two subjects: the increase of medical expenses, the lack of medical workers, may be “have” will be more appropriate for this sentence. (3). Line 40-41 However, current commercial measurement systems are not suitable for continuous measurement because the majority of them are for stationary use and apply physical constraints. what do you want to express by this “ apply physical constraints”. (4). Line 41-42 To resolve those problems, various wearable vital sign measurement systems have been used globally. Can you give more examples or references? (5). Line 150-153 In this research, 120 data sets were prepared for PLSR by using raw data measured 120 times, which are composed of the normalized pulse wave signals and reference blood pressure. 80 data sets were used for the construction of the calibration curve, and the remaining data sets were used for validation. How to choose 80 sets of data for the construction of the calibration curve from 120 data sets? Summary The overall idea of this article is relatively novel. The attempt to calculate blood pressure from wavelength shifts measured by POF-FBG sensor is made. Although the POFFBG APG correlation is not as high as desired, the measured signals are substantially similar to those of an acceleration plethysmograph (APG), the blood pressure is measured with low error and the POF-FBG sensor could measure the pulse wave signals with SN ratio at least 8 times higher than the Silica-FBG sensor. Furthermore, pulse wave signals should be measured under a wide range of reference blood pressures to confirm the reliability of POF-FBG sensors for its implementation in our daily life.

Author Response

Dear reviewer 1

 

I am Yuki Haseda from Shinshu University.

Thank you very much for reviewing our manuscript despite your busy schedule.

I will submit the covering letter about our manuscript (ID : sensors-643365) under the major revisions to you.

 

Please see the attachment.

 

We look forward to hearing from you regarding our submission.
Also we would be glad to respond to any further questions and comments that you may have.

 

Author Response File: Author Response.pdf

Reviewer 2 Report

The article is quite innovative from a technical point of view and represent a potential improvement for the state of the art.

However, the signal processing steps described in section 3.2 (from row 120 to row158) need to be clearer, for example, adding some block diagrams related to signal processing and analysis.

The proposed sensor should work at different temperatures, for this reason, the authors should add some considerations on the thermal dependence (if there) of the sensing performance.

Author Response

Dear reviewer 2

 

I am Yuki Haseda from Shinshu University.

Thank you very much for reviewing our manuscript despite your busy schedule.

I will submit covering letter about our manuscript (ID : sensors-643365) under the major revisions to you.

 

Please see the attachment.

 

We look forward to hearing from you regarding our submission.
Also we would be glad to respond to any further questions and comments that you may have.

 

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

it can be accepted in present.