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Medicina
Volume 51
Issue 4
10.1016/j.medici.2015.07.004
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Article

Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction

by
Edita Jankauskienė
1,*,
Paulius Orda
2,
Eglė Rumbinaitė
1,
Diana Žaliaduonytė-Pekšienė
1,
Rasa Steponavičiutė
3,
Aurelija Krasauskienė
4,
Jolanta Justina Vaškelytė
1 and
Robertas Bunevičius
5
1
Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
2
Faculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
3
Department of Laboratory Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
4
Department of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
5
Behavioral Medicine Institute, Medical Academy, Lithuanian University of Health Sciences, Palanga, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2015, 51(4), 209-216; https://doi.org/10.1016/j.medici.2015.07.004
Submission received: 9 October 2014 / Revised: 1 May 2015 / Accepted: 18 July 2015 / Published: 1 August 2015
Versions Notes

Abstract

Background and objective: Low-T3 syndrome is common in patients with acute myocardial infarction (AMI). Recent experimental and clinical data have suggested a potential negative impact of low-T3 syndrome on myocardial function in patients with AMI. The aim of this study was to assess left ventricular (LV) myocardial function in patients with low-T3 syndrome and to investigate the association between hormonal profile and the severity of LV dysfunction using speckle-tracking echocardiography (STE). Materials and methods: In 130 patients with first-onset ST-segment elevation acute myocardial infarction (STEMI), conventional 2D and speckle-tracking echocardiography within 48–72 h after the hospitalization was performed, and blood samples for TSH, fT4, fT3, and anti-TPO levels were obtained to investigate thyroid hormone production within 24 h and on the fourth day after the onset of STEMI symptoms. Results: The patients were divided into two groups according to their serum level of fT3: group 1 with fT3 concentration below 3.2 pmol/L (n = 34) and group 2 with normal fT3 (>3.2 pmol/L) level (n = 96). LV ejection fraction (EF) tended to be lower in the low fT3 group. The systolic longitudinal strain did not differ between the groups, but the late diastolic longitudinal strain rate was lower in group 1 (P = 0.011). The systolic basal LV rotation positively correlated with the level of fT3 (r = 0.4; P < 0.001), while a negative correlation was detected between myocardial rotational parameters – systolic apical rotation (r = 0.2; P < 0.05), torsion (r = 0.3; P < 0.001), and diastolic apical rotation rate (r = 0.3; P < 0.01) – and fT3 levels. Conclusions: The late diastolic longitudinal LV strain rate and LV rotation evaluated by speckle-tracking echocardiography were impaired in patients with low-T3 syndrome after AMI.
Keywords: Acute myocardial infarction; Low-T3 syndrome; Speckle-tracking echocardiography; Systolic and diastolic left ventricular function Acute myocardial infarction; Low-T3 syndrome; Speckle-tracking echocardiography; Systolic and diastolic left ventricular function

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MDPI and ACS Style

Jankauskienė, E.; Orda, P.; Rumbinaitė, E.; Žaliaduonytė-Pekšienė, D.; Steponavičiutė, R.; Krasauskienė, A.; Vaškelytė, J.J.; Bunevičius, R. Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction. Medicina 2015, 51, 209-216. https://doi.org/10.1016/j.medici.2015.07.004

AMA Style

Jankauskienė E, Orda P, Rumbinaitė E, Žaliaduonytė-Pekšienė D, Steponavičiutė R, Krasauskienė A, Vaškelytė JJ, Bunevičius R. Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction. Medicina. 2015; 51(4):209-216. https://doi.org/10.1016/j.medici.2015.07.004

Chicago/Turabian Style

Jankauskienė, Edita, Paulius Orda, Eglė Rumbinaitė, Diana Žaliaduonytė-Pekšienė, Rasa Steponavičiutė, Aurelija Krasauskienė, Jolanta Justina Vaškelytė, and Robertas Bunevičius. 2015. "Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction" Medicina 51, no. 4: 209-216. https://doi.org/10.1016/j.medici.2015.07.004

APA Style

Jankauskienė, E., Orda, P., Rumbinaitė, E., Žaliaduonytė-Pekšienė, D., Steponavičiutė, R., Krasauskienė, A., Vaškelytė, J. J., & Bunevičius, R. (2015). Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction. Medicina, 51(4), 209-216. https://doi.org/10.1016/j.medici.2015.07.004

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