Climate Change, Public Health and Human Rights
1. Introduction
2. Human Rights Must Be Central to the Climate Change Response
3. A Global Health and Human Rights Threat: Responding to Climate Change through Mitigation and Adaptation
3.1. The Health and Human Rights Threat of Climate Change
3.1.1. Rising Temperatures
3.1.2. Deteriorating Air Quality
3.1.3. Intensifying Extreme Weather
3.1.4. Emerging Infectious Diseases
3.1.5. Declining Nutrition
3.1.6. Deteriorating Water and Sanitation
3.1.7. Worsening Mental Health
3.2. The Human Rights Foundation for the Climate Change Response
3.2.1. Climate Change Mitigation
3.2.2. Climate Change Adaptation
Availability—Health systems should adapt in ways that ensure a sufficient number of functioning facilities, goods, services, and programs to address the health harms of climate change.
Accessibility—Health systems must ensure four overlapping dimensions of accessibility, including (1) accessibility without discrimination; (2) physical accessibility of goods, services, facilities, and determinants, safely within reach, despite geographical challenges, population displacements, and weather patterns; (3) economic accessibility through affordable goods and services; and (4) information accessibility, allowing all individuals to seek, receive, and impart information concerning health, including information regarding the health implications of climate change [62].
Acceptability—Health interventions must be acceptable not only to individual beneficiaries but must also be ethically and culturally appropriate, including special emphasis on ensuring acceptability for those most likely to be impacted by, and therefore vulnerable to, climate change.
Quality—The climate change response will require scientifically and medically appropriate services and technologies, including in measures for protection against climate change and response to health harms [61].
4. Rising Efforts to Mainstream Human Rights in Climate Change Policy
Climate change impacts, directly and indirectly, an array of internationally guaranteed human rights. States (duty-bearers) have an affirmative obligation to take effective measures to prevent and redress these climate impacts, and therefore, to mitigate climate change, and to ensure that all human beings (rights-holders) have the necessary capacity to adapt to the climate change crisis [69].
Funding
Acknowledgments
Conflicts of Interest
References
- Gostin, L.O. Public Health, Ethics, and Human Rights: A Tribute to the Late Jonathan Mann. J. Law. Med. Ethics 2001, 29, 121–130. [Google Scholar] [CrossRef] [Green Version]
- Shelton, D. Human Rights and the Environment: What Specific Environmental Rights Have Been Recognized. Denver J. Int. Law Policy 2006, 35, 129–171. [Google Scholar]
- UN General Assembly. Universal Declaration of Human Rights. 1948. Available online: https://www.un.org/en/about-us/universal-declaration-of-human-rights (accessed on 10 December 2021).
- UN General Assembly. International Covenant on Civil and Political Rights. 1966. Available online: https://www.ohchr.org/en/professionalinterest/pages/ccpr.aspx (accessed on 10 December 2021).
- UN General Assembly. International Covenant on Economic, Social and Cultural Rights. 1966. Available online: https://www.ohchr.org/en/professionalinterest/pages/cescr.aspx (accessed on 10 December 2021).
- Willis, M. Economic Development, Environmental Protection, and the Right to Health. Georget. Environ. Law Rev. 1996, 9, 200–202. [Google Scholar]
- Kiss, A.C.; Shelton, D. International Environmental Law. Grundwerk; Transnational Public: Ardsley-on-Hudson, NY, USA, 1991; ISBN 978-0-941320-67-2. [Google Scholar]
- Samet, J.M.; Gruskin, S. Air Pollution, Health, and Human Rights. Lancet Respir. Med. 2015, 3, 98–100. [Google Scholar] [CrossRef] [Green Version]
- WHO, Constitution of the World Health Organization: Preamble. 1948. Available online: https://apps.who.int/gb/bd/PDF/bd47/EN/constitution-en.pdf (accessed on 10 December 2021).
- Knox, J.H. Linking Human Rights and Climate Change at the United Nations. Harv. Environ. Law Rev. 2009, 33, 477–498. [Google Scholar]
- Limon, M. Human Rights and Climate Change: Constructing Case for Political Action. Harv. Environ. Law Rev. 2009, 33, 439–476. [Google Scholar]
- Gao, J.; Kovats, S.; Vardoulakis, S.; Wilkinson, P.; Woodward, A.; Li, J.; Gu, S.; Liu, X.; Wu, H.; Wang, J.; et al. Public Health Co-Benefits of Greenhouse Gas Emissions Reduction: A Systematic Review. Sci. Total Environ. 2018, 627, 388–402. [Google Scholar] [CrossRef]
- Romanello, M.; McGushin, A.; Di Napoli, C.; Drummond, P.; Hughes, N.; Jamart, L.; Kennard, H.; Lampard, P.; Rodriguez, B.S.; Arnell, N.; et al. The 2021 report of the Lancet Countdown on health and climate change: Code red for a healthy future. Lancet 2021, 398, 1619–1662. [Google Scholar] [CrossRef]
- Knox, J.H. Chapter 4. Diagonal Environmental Rights. In Universal Human Rights and Extraterritorial Obligations; Gibney, M., Skogly, S., Eds.; University of Pennsylvania Press: State College, PA, USA, 2010; pp. 82–103. ISBN 978-0-8122-4215-7. [Google Scholar]
- UN General Assembly. United Nations Conference on the Human Environment; UN General Assembly: New York, NY, USA, 1973; Available online: https://undocs.org/en/A/CONF.48/14/Rev.1 (accessed on 23 January 2022).
- IPCC. Climate Change: The IPCC 1990 and 1992 Assessments. Canada. 1992. Available online: https://www.ipcc.ch/report/climate-change-the-ipcc-1990-and-1992-assessments/ (accessed on 23 January 2022).
- Shelton, D. Human Rights, Environmental Rights, and the Right to Environment. Stanf. J. Int. Law 1991, 28, 103–138. [Google Scholar]
- UN General Assembly. United Nations Framework Convention on Climate Change; UN General Assembly: New York, NY, USA, 1994; Available online: https://unfccc.int/files/essential_background/background_publications_htmlpdf/application/pdf/conveng.pdf (accessed on 23 January 2022).
- UN Commission on Human Rights. Human Rights and the Environment; UN Commission on Human Rights: Geneva, Switzerland, 1995; Available online: https://undocs.org/E/CN.4/Sub.2/1994/9 (accessed on 23 January 2022).
- Phelan, A.L. The Environment, a Changing Climate, and Planetary Health. In Foundations of Global Health & Human Rights; Gostin, L.O., Meier, B.M., Eds.; OUP: New York, NY, USA, 2020. [Google Scholar]
- WHO. Climate Change and Health. 2021. Available online: https://www.who.int/news-room/fact-sheets/detail/climate-change-and-health (accessed on 7 February 2022).
- McMichael, A.J.; Friel, S.; Nyong, A.; Corvalan, C. Global Environmental Change and Health: Impacts, Inequalities, and the Health Sector. BMJ 2008, 336, 191–194. [Google Scholar] [CrossRef] [Green Version]
- WHO. Heat and Health. 2018. Available online: https://www.who.int/news-room/fact-sheets/detail/climate-change-heat-and-health (accessed on 7 February 2022).
- NIH. Effects of Heat. 2017. Available online: https://www.niehs.nih.gov/research/programs/climatechange/health_impacts/heat/index.cfm (accessed on 7 February 2022).
- UN Human Rights Council. Safe Climate: A Report of the Special Rapporteur on Human Rights and the Environment; UN Human Rights Council: Geneva, Switzerland, 2019; Available online: https://www.ohchr.org/Documents/Issues/Environment/SREnvironment/Report.pdf (accessed on 12 March 2022).
- UN OHCHR. Understanding Human Rights and Climate Change. In Proceedings of the 21st Conference of Parties to the UNFCCC (COP21), Le Bourget, France, 30 November–13 December 2015; Available online: https://www.ohchr.org/Documents/Issues/ClimateChange/COP21.pdf (accessed on 12 March 2022).
- UN. International Day of Clean Air for Blue Skies. 2021. Available online: https://www.un.org/en/observances/clean-air-day (accessed on 7 February 2022).
- Patz, J.A.; Frumkin, H.; Holloway, T.; Vimont, D.J.; Haines, A. Climate Change: Challenges and Opportunities for Global Health. JAMA 2014, 312, 1565. [Google Scholar] [CrossRef]
- Boyd, D.R. The Human Right to Breathe Clean Air. Ann. Glob. Health 2019, 85, 146. [Google Scholar] [CrossRef]
- UN OHCHR. Convention on the Rights of the Child; UN OCHHR: Geneva, Switzerland, 1989; Available online: https://www.ohchr.org/en/professionalinterest/pages/crc.aspx (accessed on 19 March 2022).
- UN Human Rights Council. Issue of Human Rights Obligations Relating to the Enjoyment of A Safe, Clean, Healthy and Sustainable Environment; UN Human Rights Council: Geneva, Switzerland, 2019; Available online: https://documents-dds-ny.un.org/doc/UNDOC/GEN/G19/002/54/PDF/G1900254.pdf?OpenElement (accessed on 19 March 2022).
- UN Human Rights Council. Human Rights Obligations Relating to the Enjoyment of A Safe, Clean, Health and Sustainable Environment; UN Human Rights Council: Geneva, Switzerland, 2018; Available online: https://undocs.org/A/73/188 (accessed on 19 March 2022).
- Ebi, K.L.; Hess, J.J. Health Risks Due to Climate Change: Inequity in Causes and Consequences: Study Examines Health Risks Due to Climate Change. Health Aff. 2020, 39, 2056–2062. [Google Scholar] [CrossRef]
- UN OHCHR. Climate Change and the Right to Housing. Available online: https://www.ohchr.org/EN/Issues/Housing/Pages/ClimateChange.aspx (accessed on 7 February 2022).
- UN OHCHR. Human Rights, The Environment, and COVID-19. 2020. Available online: https://www.ohchr.org/Documents/Issues/ClimateChange/HR-environment-COVID19.pdf (accessed on 6 June 2022).
- WHO. Dengue and Severe Dengue. 2022. Available online: https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue (accessed on 7 February 2022).
- Meier, B.M.; Evans, D.P.; Phelan, A. Rights-Based Approaches to Preventing, Detecting, and Responding to Infectious Disease. In Infectious Diseases in the New Millennium; Eccleston-Turner, M., Brassington, I., Eds.; International Library of Ethics, Law, and the New Medicine; Springer International Publishing: Cham, Switzerland, 2020; Volume 82, pp. 217–253. [Google Scholar]
- Sekalala, S.; Harrington, J. Communicable Diseases, Health Security, and Human Rights: From AIDS to Ebola. In Foundations of Global Health & Human Rights; Gostin, L.O., Meier, B.M., Eds.; OUP: New York, NY, USA, 2020. [Google Scholar]
- Ayala, A.; Meier, B.M. A Human Rights Approach to the Health Implications of Food and Nutrition Insecurity. Pub. Health Rev. 2017, 38, 10. [Google Scholar] [CrossRef] [Green Version]
- Food and Agriculture Organization of the UN. The State of Food Security and Nutrition in the World. 2018. Available online: https://www.fao.org/3/i9553en/i9553en.pdf (accessed on 14 July 2022).
- USDA. Climate Change Global Food Security and the US Food System. 2015. Available online: https://www.usda.gov/sites/default/files/documents/CCFS_Executive_Summary.pdf (accessed on 14 July 2022).
- CESCR. General Comment No. 12: The Right to Adequate Food (Art. 11); CESCR: Geneva, Switzerland, 1999; Available online: https://www.refworld.org/pdfid/4538838c11.pdf (accessed on 14 July 2022).
- IPCC. Climate Change 2014: Synthesis Report; IPCC: Geneva, Switzerland, 2015; Available online: https://archive.ipcc.ch/report/ar5/syr/ (accessed on 20 July 2022).
- CESCR. General Comment No. 15: The Right to Water (Arts. 11 and 12 of the Covenant); CESCR: New York, NY, USA, 2003. [Google Scholar]
- UN General Assembly. 64/292: The Human Right to Water and Sanitation; UN General Assembly: New York, NY, USA, 2010; Available online: https://documents-dds-ny.un.org/doc/UNDOC/GEN/N09/479/35/PDF/N0947935.pdf?OpenElement (accessed on 28 July 2022).
- UN Human Rights Council. Special Thematic Report on Climate Change and the Human Rights to Water and Sanitation; UN Human Rights Council: Geneva, Switzerland, 2022; Available online: https://www.ohchr.org/en/documents/thematic-reports/special-thematic-report-climate-change-and-human-rights-water-and (accessed on 28 July 2022).
- Majeed, H.; Lee, J. The Impact of Climate Change on Youth Depression and Mental Health. Lancet Planet. Health 2017, 1, e94–e95. [Google Scholar] [CrossRef]
- Rao, M.; Powell, R.A. The Climate Crisis and the Rise of Eco-Anxiety. BMJ Opinion. 2021. Available online: https://blogs.bmj.com/bmj/2021/10/06/the-climate-crisis-and-the-rise-of-eco-anxiety/#content (accessed on 7 October 2021).
- Clayton, S.; Manning, C.; Krygsman, K.; Speiser, M. Mental Health and Our Changing Climate: Impacts, Implications, and Guidance; American Psychological Association and ecoAmerica: Washington, DC, USA, 2017; Available online: https://www.apa.org/news/press/releases/2017/03/mental-health-climate.pdf (accessed on 7 October 2021).
- UN Human Rights Council. Report of the Special Rapporteur on the Right of Everyone to the Enjoyment of the Highest Attainable Standard of Physical Health; UN Human Rights Council: Geneva, Switzerland, 2017; Available online: https://documents-dds-ny.un.org/doc/UNDOC/GEN/G17/076/04/PDF/G1707604.pdf?OpenElement (accessed on 22 September 2022).
- Health Care without Harm and ARUP. Health Care’s Climate Footprint: How the Health Sector Contributes to the Global Climate Crisis and Opportunities for Action. 2019. Available online: https://noharm-global.org/sites/default/files/documents-files/5961/HealthCaresClimateFootprint_092319.pdf (accessed on 22 September 2022).
- UN Human Rights Council. General Comment No. 36 (2018) on Article 6 of the International Covenant on Civil and Political Rights, on the Right to Life; UN Human Rights Council: Geneva, Switzerland, 2018; Available online: https://tbinternet.ohchr.org/Treaties/CCPR/Shared%20Documents/1_Global/CCPR_C_GC_36_8785_E.pdf (accessed on 29 September 2022).
- UN Human Rights Council. Five UN Human Rights Treaty Bodies Issue A Joint Statement on Human Rights and Climate Change. 2019. Available online: https://www.ohchr.org/EN/NewsEvents/Pages/DisplayNews.aspx?NewsID=24998 (accessed on 7 February 2022).
- Levy, B.S.; Patz, J.A. Climate Change, Human Rights, and Social Justice. Annals Glob. Health 2015, 81, 310. [Google Scholar] [CrossRef]
- UN CRC. Convention on the Rights of the Child 88 Session (6 September 2021–24 September 2021). 2021. Available online: https://tbinternet.ohchr.org/_layouts/15/treatybodyexternal/SessionDetails1.aspx?SessionID=1351&Lang=en (accessed on 7 February 2022).
- Chong, D. The sustainable development goals and climate change. Soc. Alternat. 2018, 37, 43–48. [Google Scholar]
- UN General Assembly. Draft Decision -/CP.16, Outcome of the Work of the Ad Hoc Working Group on Long-Term Cooperative Action under the Convention; UN General Assembly: New York, NY, USA, 2012; Available online: https://unfccc.int/files/meetings/cop_16/application/pdf/cop16_lca.pdf (accessed on 22 December 2021).
- Bustreo, F.; Doebbler, C. The Rights-Based Approach to Health. In Foundations of Global Health & Human Rights; Gostin, L.O., Meier, B.M., Eds.; OUP: New York, NY, USA, 2020; Chapter 4. [Google Scholar]
- Pedersen, O.W. The Janus-Head of Human Rights and Climate Change: Adaptation and Mitigation. Nord J. Int’l. L. 2011, 80, 403–423. [Google Scholar] [CrossRef]
- Kovats, S.; Ebi, K.L.; Bettina Menne, B. Methods of Assessing Human Health Vulnerability and Public Health Adaptation to Climate Change; Kovats, S., Ed.; Health and Global Environment Change; World Health Organization, Regional Office for Europe [u.a.]: Copenhagen, Denmark, 2003; ISBN 978-92-890-1090-0. [Google Scholar]
- CESCR. General Comment No. 14: The Right to the Highest Attainable Standard of Health (Art. 12); CESCR: Geneva, Switzerland, 2000; Available online: https://www.refworld.org/pdfid/4538838d0.pdf (accessed on 10 December 2021).
- Hesselman, M.M.E.; Toebes, B. The Human Right to Health and Climate Change: A Legal Perspective. SSRN J. 2015. [Google Scholar] [CrossRef] [Green Version]
- Benevolenza, M.A.; DeRigne, L. The Impact of Climate Change and Natural Disasters on Vulnerable Populations: A Systematic Review of Literature. J. Human Behav. Soc. Environ. 2019, 29, 266–281. [Google Scholar] [CrossRef]
- Satterthwaite, D.; Archer, D.; Colenbrander, S.; Dodman, D.; Hardoy, J.; Mitlin, D.; Patel, S. Building Resilience to Climate Change in Informal Settlements. One Earth 2020, 2, 143–156. [Google Scholar] [CrossRef] [Green Version]
- Atwoli, L.; Baqui, A.H.; Benfield, T.; Bosurgi, R.; Godlee, F.; Hancocks, S.; Horton, R.; Laybourn-Langton, L.; Monteiro, C.A.; Norman, I.; et al. Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health. Nutr. Rev. 2021, 79, 1183–1185. [Google Scholar] [CrossRef]
- WHO. COP24 Special Report-Health and Climate Change; World Health Organization: Geneva, Switzerland, 2018; Available online: https://apps.who.int/iris/bitstream/handle/10665/276405/9789241514972-eng.pdf (accessed on 7 October 2022).
- International Institute for Sustainable Development. World Health Day 2008 Focuses on Climate Change. 2008. Available online: http://sdg.iisd.org/news/world-health-day-2008-focuses-on-climate-change/ (accessed on 7 February 2022).
- WHO. Protecting Health from Climate Change-World Health Day 2008; World Health Organization: Geneva, Switzerland, 2008; Available online: https://apps.who.int/iris/handle/10665/43867 (accessed on 21 April 2022).
- UN Human Rights Council. Report of the Office of the United Nations High Commissioner for Human Rights on the Relationship between Climate Change and Human Rights; UN Human Rights Council: Geneva, Switzerland, 2009; Available online: https://documents-dds-ny.un.org/doc/UNDOC/GEN/G09/103/44/PDF/G0910344.pdf?OpenElement (accessed on 21 April 2022).
- UN General Assembly. Report of the Conference of the Parties on Its Sixteenth Session, Held in Cancun from 29 November to 10 December 2010: Decisions Adopted by the Conference of the Parties; UN General Assembly: New York, NY, USA, 2010; Available online: https://unfccc.int/documents/6527 (accessed on 21 April 2022).
- UN Human Rights Council. Analytical Study on the Relationship between Human Rights and the Environment; UN Human Rights Council: Geneva, Switzerland, 2011; Available online: https://ap.ohchr.org/documents/dpage_e.aspx?si=A/HRC/19/34 (accessed on 21 April 2022).
- UN General Assembly. Paris Agreement to the United Nations Framework Convention on Climate Change; UN General Assembly: New York, NY, USA, 2015; Available online: https://unfccc.int/sites/default/files/english_paris_agreement.pdf (accessed on 21 April 2022).
- WHO. Conference on Health and Climate Change; World Health Organization: Geneva, Switzerland, 2014; Available online: https://cdn.who.int/media/docs/default-source/climate-change/conference-report-of-1st-global-conference-on-health-and-climate-change.pdf?sfvrsn=45bae339 (accessed on 21 April 2022).
- Human Rights Watch. Human Rights in Climate Pact Under Fire. 2015. Available online: https://www.hrw.org/news/2015/12/07/human-rights-climate-pact-under-fire# (accessed on 7 February 2022).
- UN News. UN Emissions Report: World on Course for More than 3-degree Spike, Even If Climate Commitments Are Met. 2019. Available online: https://news.un.org/en/story/2019/11/1052171 (accessed on 7 February 2022).
- Chan, M. WHO Director-General addresses Human Rights Council on Climate Change. 2016. Available online: https://www.who.int/director-general/speeches/detail/who-director-general-addresses-human-rights-council-on-climate-change (accessed on 7 February 2022).
- UN Climate Change News. First-Ever Global Conference on Air Pollution and Health. 2018. Available online: https://unfccc.int/news/first-ever-global-conference-on-air-pollution-and-health (accessed on 7 February 2022).
- Ghebreyesus, T.A. Closing Address at High-Level Action Day, First WHO Global Conference on Air Pollution and Health. 2018. Available online: https://www.who.int/director-general/speeches/detail/closing-address-at-high-level-action-day-first-who-global-conference-on-air-pollution-and-health (accessed on 7 February 2022).
- Human Rights Watch. The Case for a Right to a Healthy Environment. 2018. Available online: https://www.hrw.org/news/2018/03/01/case-right-healthy-environment (accessed on 7 February 2022).
- UN News. The Human Right to A Clean and Healthy Environment: 6 Things You Need to Know. 2021. Available online: https://news.un.org/en/story/2021/10/1103082 (accessed on 7 February 2022).
- Call for the Global Recognition of the Right to a Healthy Environment. 2020. Available online: http://healthyenvironmentisaright.org/ (accessed on 7 February 2022).
- UN General Assembly. Glasgow Climate Pact to the United Nations Framework Convention on Climate Change (Draft Decision); UN General Assembly: New York, NY, USA, 2021; Available online: https://unfccc.int/sites/default/files/resource/cp2021_L13E.pdf (accessed on 21 April 2022).
- Bachelet, M. Statement by the UN High Commissioner for Human Rights Michelle Bachelet on the COP-26 Meeting. 2021. Available online: https://www.ohchr.org/en/2021/10/statement-un-high-commissioner-human-rights-michelle-bachelet-cop-26-meeting (accessed on 7 February 2022).
- UK Environment Agency. Adapt or Die, Says Environment Agency. 2021. Available online: https://www.gov.uk/government/news/adapt-or-die-says-environment-agency (accessed on 7 February 2022).
- Amnesty International. COP26 Outcome: 12 Months to Take Climate Action that Delivers on Human Rights. 2021. Available online: https://www.amnesty.org/en/documents/ior40/4989/2021/en/ (accessed on 7 February 2022).
- Burki, T.K. “Phasedown” of Coal Use after COP26 Negotiations. Lancet Resp. Med. 2022, 10, 10. [Google Scholar] [CrossRef]
- UN General Assembly. The Human Right to A Clean, Healthy and Sustainable Environment. 2022. Available online: https://digitallibrary.un.org/record/3983329?ln=en (accessed on 2 September 2022).
- Buse, K.; Hesselman, M.; Meier, B.M. The human right to a healthy environment—Time for the public health community to take urgent action. BMJ 2022, 378, o2313. [Google Scholar] [CrossRef]
- United Nations. With 161 Votes in Favour, 8 Abstentions, General Assembly Adopts Landmark Resolution Recognizing Clean, Healthy, Sustainable Environment as Human Right|UN Press. United Nations. 2022. Available online: https://press.un.org/en/2022/ga12437.doc.htm (accessed on 2 September 2022).
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Meier, B.M.; Bustreo, F.; Gostin, L.O. Climate Change, Public Health and Human Rights. Int. J. Environ. Res. Public Health 2022, 19, 13744. https://doi.org/10.3390/ijerph192113744
Meier BM, Bustreo F, Gostin LO. Climate Change, Public Health and Human Rights. International Journal of Environmental Research and Public Health. 2022; 19(21):13744. https://doi.org/10.3390/ijerph192113744
Chicago/Turabian StyleMeier, Benjamin Mason, Flavia Bustreo, and Lawrence O. Gostin. 2022. "Climate Change, Public Health and Human Rights" International Journal of Environmental Research and Public Health 19, no. 21: 13744. https://doi.org/10.3390/ijerph192113744
APA StyleMeier, B. M., Bustreo, F., & Gostin, L. O. (2022). Climate Change, Public Health and Human Rights. International Journal of Environmental Research and Public Health, 19(21), 13744. https://doi.org/10.3390/ijerph192113744