Correlations between Social Isolation and Functional Decline in Older Adults after Lower Limb Fractures Using Multimodal Sensors: A Pilot Study
Abstract
:1. Introduction
2. Literature Review
2.1. Studies Assessing SI Using Sensors
2.2. Studies Assessing FD Using Sensors
3. Gaps in the Literature
4. Methods
4.1. Clinical Data Collection
4.1.1. Social Isolation Scale
4.1.2. Oxford Hip Score and Oxford Knee Score
4.1.3. Timed up and Go Test
4.1.4. 30 s Chair Stand
4.2. Sensor Data Collected Using MAISON
4.3. Feature Extraction
5. Results and Analysis
5.1. Demographic Data
5.2. Clinical Data
5.3. Sensor Data
5.4. Correlation Analyses
5.4.1. Daily Correlation Analysis
- Four different daily-feature csv files were created for each type of clinical data, since the types of data missing for each clinical data were different. For example, in the daily feature file with respect to TUG, the days where TUG was missing were removed. The four resulting daily feature files consisted of the following: (1) daily features with respect to SIS, (2) daily features with respect to TUG, (3) daily features with respect to 30 s chair stand, (4) daily features with respect to Oxford Hip Score and Oxford Knee Score.
- Using Python programming language and the Visual Studio Code IDE, the Spearman’s correlation was calculated for every column of the daily features. In this step, any correlations with a p value less than (statistically significant) were kept, and the rest were marked as “0” in the correlation matrix.
- For each resulting correlation matrix generated in step 2, a second round of analysis was conducted in order to remove redundant features. In this step, every two features with an absolute correlation value higher than were deemed as “redundant”, and one of the two features was removed from the correlation matrix.
5.4.2. Biweekly Correlation Analysis
6. Discussion and Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
Abbreviations
SI | Social Isolation |
OA | Older Adult |
FD | Functional Decline |
MAISON | Multimodal AI-based Sensor platform for Older iNdividuals |
SIS | Social Isolation Scale |
TUG | Timed Up and Go test |
TRI | Toronto Rehabilitation Institute |
UHN | University Health Network |
GPS | Global Positioning System |
FE | Feature Extraction |
BPM | Beats Per Minute |
PSG | Polysonomography |
Appendix A
Item | Response (Score) |
---|---|
(1) How would you describe the pain your usually have in your hip? | None (1) |
Very mild (2) | |
Mild (3) | |
Moderate (4) | |
Severe (5) | |
(2) Have you been troubled by pain from your hip in bed at night? | No nights (1) |
Only 1 or 2 nights (2) | |
Some nights (3) | |
Most nights (4) | |
Every night (5) | |
(3) Have you had any sudden, severe pain (shooting, stabbing, or spasms) from your affected hip? | No days (1) |
Only 1 or 2 days (2) | |
some days (3) | |
Most days (4) | |
Every day (5) | |
(4) Have you been limping when walking because of your hip? | Rarely/never (1) |
Sometimes or just at first (2) | |
Often, not just at first (3) | |
Most of the time (4) | |
All of the time (5) | |
(5) For how long have you been able to walk before the pain in your hip becomes severe (with or without a walking aid)? | No pain for 30 min or more (1) |
16 to 30 min (2) | |
5 to 15 min (3) | |
Around the house only (4) | |
Not at all (5) | |
(6) Have you been able to climb a flight of stairs? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) | |
(7) Have you been able to put on a pair of socks, stockings or tights? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) | |
(8) After a meal (sat at a table), how painful has it been for you to stand up from a chair because of your hip? | Not at all painful (1) |
Slightly painful (2) | |
Moderately painful (3) | |
Very painful (4) | |
Unbearable (5) | |
(9) Have you had any trouble getting in and out of a car or using public transportation because of your hip? | No trouble at all (1) |
Very little trouble (2) | |
Moderate trouble (3) | |
Extreme difficulty (4) | |
Impossible to do (5) | |
(10) Have you had any trouble with washing and drying yourself (all over) because of your hip? | No trouble at all (1) |
Very little trouble (2) | |
Moderate trouble (3) | |
Extreme difficulty (4) | |
Impossible to do (5) | |
(11) Could you do the household shopping on your own? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) | |
(12) How much has pain from your hip interfered with your usual work, including housework? | Not at all (1) |
A little bit (2) | |
Moderately (3) | |
Greatly (4) | |
Totally (5) |
Item | Response (Score) |
---|---|
(1) How would you describe the pain you usually have in your knee? | None (1) |
Very mild (2) | |
Mild (3) | |
Moderate (4) | |
Severe (5) | |
(2) Have you had any trouble washing and drying yourself (all over) because of your knee? | No trouble at all (1) |
Very little trouble (2) | |
Moderate trouble (3) | |
Extreme difficulty (4) | |
Impossible to do (5) | |
(3) Have you had any trouble getting in and out of the car or using public transport because of your knee? (With or without a stick) | No trouble at all (1) |
Very little trouble (2) | |
Moderate trouble (3) | |
Extreme difficulty (4) | |
Impossible to do (5) | |
(4) For how long are you able to walk before the pain in your knee becomes s eve re? (With or without a stick) | No pain > 60 min (1) |
16–60 min (2) | |
5–15 min (3) | |
Around the house only (4) | |
Not at all—severe on walking (5) | |
(5) After a meal (sat at a table), how painful has it been for you to stand up from a chair because of your knee? | Not at all painful (1) |
Slightly painful (2) | |
moderately painful (3) | |
very painful (4) | |
Unbearable (5) | |
(6) Have you been limping when walking, because of your knee? | Rarely/never (1) |
Sometimes or just at first (2) | |
Often, not just at first (3) | |
Most of the time (4) | |
All of the time (5) | |
(7) Could you kneel down and get up again afterwards? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) | |
(8) Are you troubled by pain in your knee at night in bed? | Not at all (1) |
Only one or two nights (2) | |
Some nights (3) | |
Most nights (4) | |
Evert night (5) | |
(9) How much has pain from your knee interfered with your usual work? (including housework) | Not at all (1) |
A little bit (2) | |
Moderately (3) | |
Greatly (4) | |
Totally (5) | |
(10) Have you felt that your knee might suddenly give away or let you down? | Rarely/never (1) |
Sometimes or just at first (2) | |
Often, not at first (3) | |
Most of the time (4) | |
All the time (5) | |
(11) Could you do household shopping on your own? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) | |
(12) Could you walk down a flight of stairs? | Yes, easily (1) |
With little difficulty (2) | |
With moderate difficulty (3) | |
With extreme difficulty (4) | |
No, impossible (5) |
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Task | Baseline | Week 2 | Week 4 | Week 6 | Week 8 |
---|---|---|---|---|---|
Inpatient physical training (20–30 min) | ✓ | ||||
Sensor Installation (1 h) | ✓ | ||||
Demographic Data | ✓ | ||||
Interviews on MS Teams (1 h) | ✓ | ✓ | |||
Questionnaire completion on MS Teams (15 min) | ✓ | ✓ | ✓ | ✓ | |
Physical Tests on MS Teams (15 min) | ✓ | ✓ | ✓ | ✓ | |
Ongoing data collection with sensors (location, motion, heart rate, sleep) | ✓ | ✓ | ✓ | ✓ | |
Sensor take down (1 h) | ✓ |
Device | Data |
---|---|
Smartphone | GPS |
Smart Watch | Raw Acceleration |
Heart rate | |
Step count | |
Motion Sensor | Frequency of motion |
Sleep Sensor | Sleep metrics (i.e., sleep duration, wake up count, heart rate during sleep, etc.) |
Data Modality | Feature | Description | Function Used for Biweekly FE |
---|---|---|---|
Step | step-sum | Total number of steps per day | sum |
step-ratio | The ratio of the number of hours with step to the number of hours without step per day | mean | |
step-mean | Average number of steps in hours of a day with at least one step | mean | |
step-max | Maximum number of steps in hours of a day with at least one step | max | |
step-max-timestamp | The timestamp (hour) in which there has been a maximum number of steps a day | mean | |
Heart rate | heart rate-min | Minimum heart rate in a day | min |
heart rate-max | Maximum heart rate in a day | max | |
heart rate-mean | Mean of heart rate in a day | mean | |
heart rate-std | Standard deviation of heart rate in a day | mean | |
Acceleration | acceleration-sum | Total number of acceleration data per day | sum |
-mean | Mean of the ACC signal (g) | mean | |
-std | Standard deviation of the ACC signal (g) | mean | |
-min/-max | Minimum and maximum of the ACC signal (g) | mean | |
-ptp | Range (peak to peak) of the ACC signal (g) | mean | |
-sum | Sum of the ACC signal (g) | mean | |
-energy | Energy of the ACC signal () | mean | |
-skewness | Skewness of the ACC signal (g) | mean | |
-kurtosis | Kurtosis of the ACC signal | mean | |
-peaks | Number of the ACC signal | mean | |
-rms | Root mean square of the ACC signal (g) | mean | |
-lineintegral | Integral under the ACC signal | mean | |
-n-above-mean | Number of the ACC signal above the mean | mean | |
-n-below-mean | Number of the ACC signal below the mean | mean | |
-n-sign-changes | Number of changes in the ACC signal slope | mean | |
-iqr | Interquartile range between the 25th and 75th percentiles of the ACC signal (g) | mean | |
-iqr-5-95 | Interquartile range between the 5th and 95th percentiles of the ACC signal (g) | mean | |
-pct-5 | 5th percentile of the ACC signal | mean | |
-pct-95 | 95th percentile of the ACC signal | mean | |
-entropy | Entropy of the ACC signal | mean | |
-perm-entropy | Permutation entropy of the ACC signal | mean | |
-svd-entropy | Singular value decomposition of the ACC signal | mean | |
Position | position-count | Total number of position data per day | sum |
position-duration | The duration (in minutes) of being outside of the home in a day | sum | |
position-maximum-distance | The maximum distance traveled from home in a day | max | |
Time spent outside (mins) | Amount of time spent outside of the home in a day | sum | |
Distance travelled from home (km) | Distance traveled from the home in a day | sum | |
Motion | motion-sum | Total number of motions per day | sum |
motion-ratio | The ratio of the number of hours with motion to the number of hours without motion per day | mean | |
motion-mean | Average number of motions in hours of a day with at least one motion | mean | |
motion-max | Maximum number of motions in hours of a day with at least one motion | max | |
motion-max-timestamp | The timestamp (hour) in which there has been a maximum number of motions a day | mean | |
Sleep | totalsleepduration | Total sleep duration (hours) | sum |
deepsleepduration | Deep sleep duration (hours) | sum | |
lightsleepduration | Light sleep duration (hours) | sum | |
remsleepduration | REM sleep duration (hours) | sum | |
snoring | Snoring duration (hours) | sum | |
durationtosleep | Duration to sleep (hours) | mean | |
durationtowakeup | Duration to wake up (hours) | mean | |
wakeupcount | Wake up count (count) | sum | |
hr-average | Mean of heart rate during sleep | mean | |
hr-min | Minimum heart rate during sleep | min | |
hr-max | Maximum heart rate during sleep | max |
Category | Variable | Mean (SD) or (%) |
---|---|---|
Age | Mean (SD) | () |
60–70 | 5 (%) | |
70–80 | 1 (%) | |
80–90 | 2 (25%) | |
Gender | Male | 1 (%) |
Female | 7 (%) | |
Type of fracture | Hip | 4 (50%) |
Pelvis | 2 (25%) | |
Femur | 1 (%) | |
Hip Replacement | 1 (%) | |
Ethnicity | Caucasian | 7 (%) |
African-Canadian | 1 (%) | |
Relationship Status | Single | 3 (%) |
Married | 1 (%) | |
Widowed | 1 (%) | |
Separated | 1 (%) | |
Divorced | 2 (25%) | |
Employment Status | Unemployed | 1 (%) |
Employed | 3 (%) | |
Retired | 2 (25%) | |
Other | 2 (25%) |
Timeline | Variable | Mean (SD) |
---|---|---|
Week 2 | TUG (seconds) | () |
30 s chair stand | () | |
SIS | 25 () | |
Oxford Hip Score | () | |
Oxford Knee Score | () | |
Week 4 | TUG (seconds) | () |
30 s chair stand | () | |
SIS | () | |
Oxford Hip Score | () | |
Oxford Knee Score | () | |
Week 6 | TUG (seconds) | () |
30 s chair stand | () | |
SIS | () | |
Oxford Hip Score | () | |
Oxford Knee Score | () | |
Week 8 | TUG (seconds) | () |
30 s chair stand | () | |
SIS | () | |
Oxford Hip Score | () | |
Oxford Knee Score | () |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
Oxford Hip Score—Q11 | hr-average | |
Oxford Knee Score—Q11 | hr-average | |
Oxford Knee Score—Q10 | motion-sum | |
Oxford Knee Score—Q9 | hr-average | |
Oxford Knee Score—Q5 | motion-sum | |
Oxford Knee Score—Q4 | hr-average | |
Oxford Knee Score | hr-average | |
SIS—Q3 | hr-average | |
Oxford Hip Score—Q4 | motion-sum | |
Oxford Hip Score—Q1 | motion-sum | |
TUG | totalsleepduration | |
Oxford Hip Score—Q11 | motion-ratio |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
SIS (Connectedness) | hr-average | |
SIS (Belonging) | step-sum | |
SIS | hr-max | |
SIS—Q6 | step-sum | |
SIS | heart rate-mean | |
SIS (Belonging) | lightsleepduration | |
SIS—Q6 | durationtosleep | |
SIS | hr-average | |
SIS | heart rate-min | |
SIS—Q2 | heart rate-mean | |
SIS—Q6 | totalsleepduration | |
SIS—Q4 | lightsleepduration | |
SIS—Q5 | motion-ratio | |
SIS (Connectedness) | snoring | |
SIS (Connectedness) | totalsleepduration | |
SIS (Connectedness) | step-ratio | |
SIS (Belonging) | snoring | |
SIS—Q6 | snoring |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
Oxford Hip Score—Q11 | heart rate-mean | |
Oxford Hip Score—Q11 | heart rate-min | |
Oxford Hip Score—Q12 | hr-average | |
Oxford Hip Score—Q11 | hr-max | |
Oxford Hip Score—Q12 | heart rate-mean | |
Oxford Hip Score—Q12 | step-mean | |
Oxford Hip Score—Q10 | step-sum | |
Oxford Hip Score—Q6 | hr-max | |
Oxford Hip Score—Q4 | deepsleepduration | |
Oxford Hip Score—Q10 | heart rate-min | |
Oxford Hip Score—Q3 | lightsleepduration | |
Oxford Hip Score—Q6 | heart rate-max | |
Oxford Hip Score | heart rate-mean | |
Oxford Hip Score | step-mean | |
Oxford Hip Score | heart rate-min | |
Oxford Hip Score—Q5 | step-mean | |
Oxford Hip Score—Q1 | deepsleepduration | |
Oxford Hip Score—Q3 | motion-ratio | |
Oxford Hip Score—Q7 | motion-sum | |
Oxford Hip Score—Q4 | hr-max | |
Oxford Hip Score—Q12 | motion-ratio | |
Oxford Hip Score—Q4 | hr-average |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
Oxford Knee Score—Q10 | acceleration-sum | |
Oxford Knee Score—Q12 | hr-max | |
Oxford Knee Score—Q10 | -mean | |
Oxford Knee Score—Q12 | hr-average | |
Oxford Knee Score—Q11 | heart rate-min | |
Oxford Knee Score—Q7 | heart rate-mean | |
Oxford Knee Score—Q4 | motion-sum | |
Oxford Knee Score—Q10 | lightsleepduration | |
Oxford Knee Score | hr-max | |
Oxford Knee Score—Q12 | step-sum | |
Oxford Knee Score—Q10 | -peaks | |
Oxford Knee Score—Q12 | heart rate-max | |
Oxford Knee Score—Q7 | -svd-entropy | |
Oxford Knee Score—Q2 | hr-max | |
Oxford Knee Score | heart rate-mean | |
Oxford Knee Score—Q10 | -std | |
Oxford Knee Score—Q10 | step-ratio | |
Oxford Knee Score—Q10 | -n-sign-changes | |
Oxford Knee Score—Q7 | step-mean | |
Oxford Knee Score—Q4 | wakeupcount | |
Oxford Knee Score—Q3 | acceleration-sum | |
Oxford Knee Score—Q8 | lightsleepduration | |
Oxford Knee Score—Q7 | motion-sum | |
Oxford Knee Score—Q3 | -svd-entropy | |
Oxford Knee Score—Q10 | snoring | |
Oxford Knee Score—Q9 | motion-ratio | |
Oxford Knee Score | motion-ratio | |
Oxford Knee Score—Q7 | motion-ratio | |
Oxford Knee Score—Q11 | motion-ratio |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
30 s chair stand | hr-average | |
TUG | snoring | |
TUG | motion-sum | |
TUG | wakeupcount | |
TUG | durationtosleep | |
TUG | lightsleepduration | |
TUG | step-sum | |
30 s chair stand | snoring | |
30 s chair stand | motion-ratio |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
SIS—Q6 | durationtosleep | |
SIS (Belonging) | step-sum | |
SIS—Q6 | step-sum | |
SIS (Belonging) | lightsleepduration | |
SIS—Q3 | hr-average | |
SIS—Q4 | distance travelled from home | |
SIS—Q6 | totalsleepduration | |
SIS (Belonging) | wakeupcount | |
SIS (Belonging) | durationtosleep | |
SIS (Belonging) | distance travelled from home | |
SIS—Q1 | -pct-95 | |
SIS—Q1 | durationtosleep | |
SIS—Q6 | snoring | |
SIS (Connectedness) | -pct-95 |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
Oxford Hip Score—Q11 | hr-average | |
Oxford Hip Score—Q11 | heart rate-mean | |
Oxford Hip Score—Q11 | step-max | |
Oxford Hip Score—Q10 | step-sum | |
Oxford Hip Score—Q4 | deepsleepduration | |
Oxford Hip Score—Q4 | hr-min | |
Oxford Hip Score—Q11 | hr-max | |
Oxford Hip Score—Q3 | motion-ratio | |
Oxford Hip Score—Q3 | lightsleepduration | |
Oxford Hip Score—Q4 | durationtowakeup | |
Oxford Hip Score | -max | |
Oxford Hip Score—Q8 | -max | |
Oxford Hip Score—Q4 | motion-sum | |
Oxford Hip Score—Q2 | heart rate-std | |
Oxford Hip Score—Q1 | motion-max | |
Oxford Hip Score—Q11 | motion-ratio |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
Oxford Knee Score—Q5 | motion-max | |
Oxford Knee Score—Q11 | hr-average | |
Oxford Knee Score—Q10 | distance travelled from home | |
Oxford Knee Score—Q10 | -mean | |
Oxford Knee Score | hr-average | |
Oxford Knee Score—Q10 | motion-sum | |
Oxford Knee Score—Q10 | -peaks | |
Oxford Knee Score—Q9 | hr-max | |
Oxford Knee Score—Q7 | heart rate-mean | |
Oxford Knee Score | motion-max | |
Oxford Knee Score—Q10 | acceleration-sum | |
Oxford Knee Score—Q10 | step-ratio | |
Oxford Knee Score—Q12 | step-sum | |
Oxford Knee Score—Q11 | step-max | |
Oxford Knee Score—Q10 | durationtosleep | |
Oxford Knee Score—Q11 | durationtowakeup | |
Oxford Knee Score | motion-ratio | |
Oxford Knee Score—Q11 | motion-ratio | |
Oxford Knee Score—Q7 | motion-ratio |
Variable 1 | Variable 2 | Correlation Value |
---|---|---|
30 s chair stand | hr-max | |
TUG | step-sum | |
30 s chair stand | motion-ratio | |
TUG | totalsleepduration |
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Share and Cite
Dayyani, F.; Chu, C.H.; Abedi, A.; Khan, S.S. Correlations between Social Isolation and Functional Decline in Older Adults after Lower Limb Fractures Using Multimodal Sensors: A Pilot Study. Algorithms 2024, 17, 383. https://doi.org/10.3390/a17090383
Dayyani F, Chu CH, Abedi A, Khan SS. Correlations between Social Isolation and Functional Decline in Older Adults after Lower Limb Fractures Using Multimodal Sensors: A Pilot Study. Algorithms. 2024; 17(9):383. https://doi.org/10.3390/a17090383
Chicago/Turabian StyleDayyani, Faranak, Charlene H. Chu, Ali Abedi, and Shehroz S. Khan. 2024. "Correlations between Social Isolation and Functional Decline in Older Adults after Lower Limb Fractures Using Multimodal Sensors: A Pilot Study" Algorithms 17, no. 9: 383. https://doi.org/10.3390/a17090383
APA StyleDayyani, F., Chu, C. H., Abedi, A., & Khan, S. S. (2024). Correlations between Social Isolation and Functional Decline in Older Adults after Lower Limb Fractures Using Multimodal Sensors: A Pilot Study. Algorithms, 17(9), 383. https://doi.org/10.3390/a17090383