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Neurology International
Volume 11
Issue 1
10.4081/ni.2019.7815
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Large Left Posterior Fossa Meningioma Presenting with Quadriplegia in a Woman with History of Carbidopa-Levodopa Resistant Parkinsonism

by
Antonio Jose Reyes
1,*,
Kanterpersad Ramcharan
2,
Maria Alvarez
3,
Wesley Greaves
4 and
Fidel Rampersad
5
1
Neurology Unit, San Fernando Teaching Hospital, Trinidad and Tobago
2
Department of Medicine and 5Radiology Unit, Surgi- Med Clinic, Trinidad and Tobago
3
Department of Neurosurgery, San Fernando Teaching Hospital, Trinidad and Tobago
4
Department of Pathology and Laboratory, San Fernando Teaching Hospital, Trinidad and Tobago, West Indies
*
Author to whom correspondence should be addressed.
Neurol. Int. 2019, 11(1), 7815; https://doi.org/10.4081/ni.2019.7815
Submission received: 8 August 2018 / Revised: 16 September 2018 / Accepted: 2 January 2019 / Published: 11 March 2019

Abstract

A 56–year-old Afro-Trinidadian woman with a history of a carbidopa-levodopa resistance Parkinsonian-like syndrome for 2 years, presented with acute onset spastic quadriplegia and decreased responsiveness. Diagnosis involved clinical and MR-imaging correlation consistent with a large left posterior fossa meningioma. Surgical removal of the tumor led to complete reversibility of the neurological manifestations associated with cerebellar tonsillar herniation beyond the foramen magnum and mass effect on the brainstem, cerebellum and midbrain regions. Pathological findings were typical of a meningioma. This case demonstrates the association of a large left posterior fossa meningioma and carbidopalevodopa resistant parkinsonism in an Afro-Trinidadian woman who presented with acute onset acute quadriplegia and decreased responsiveness. This case reminds clinicians that patients with dopa unresponsiveness and/or acute neurological deficit or deterioration should be worked up for other possible causes and adds to the literature on the association of parkinsonism and intracranial space occupying lesions.
Keywords: posterior fossa mass; meningioma; parkinsonism; Parkinson disease; quadriplegia posterior fossa mass; meningioma; parkinsonism; Parkinson disease; quadriplegia

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MDPI and ACS Style

Reyes, A.J.; Ramcharan, K.; Alvarez, M.; Greaves, W.; Rampersad, F. Large Left Posterior Fossa Meningioma Presenting with Quadriplegia in a Woman with History of Carbidopa-Levodopa Resistant Parkinsonism. Neurol. Int. 2019, 11, 7815. https://doi.org/10.4081/ni.2019.7815

AMA Style

Reyes AJ, Ramcharan K, Alvarez M, Greaves W, Rampersad F. Large Left Posterior Fossa Meningioma Presenting with Quadriplegia in a Woman with History of Carbidopa-Levodopa Resistant Parkinsonism. Neurology International. 2019; 11(1):7815. https://doi.org/10.4081/ni.2019.7815

Chicago/Turabian Style

Reyes, Antonio Jose, Kanterpersad Ramcharan, Maria Alvarez, Wesley Greaves, and Fidel Rampersad. 2019. "Large Left Posterior Fossa Meningioma Presenting with Quadriplegia in a Woman with History of Carbidopa-Levodopa Resistant Parkinsonism" Neurology International 11, no. 1: 7815. https://doi.org/10.4081/ni.2019.7815

APA Style

Reyes, A. J., Ramcharan, K., Alvarez, M., Greaves, W., & Rampersad, F. (2019). Large Left Posterior Fossa Meningioma Presenting with Quadriplegia in a Woman with History of Carbidopa-Levodopa Resistant Parkinsonism. Neurology International, 11(1), 7815. https://doi.org/10.4081/ni.2019.7815

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