Development of Parkinsonism in a Patient with Central Pontine Myelinolysis

Round 1

Reviewer 1 Report

Dear Editor,

Thank you for giving me the privilege to review the submitted interesting images. In the manuscript entitled “Development of Parkinsonism in a patient with Central Pontine Myelinolysis”, the authors have provided a case report on parkinsonism associated Movement disorders as a consequence of ODS. The article can be accepted, I trust that the article will be of interest to potential readers. Below are some suggestions to authors.

1.      In Abstract…it should be ….Osmotic demyelination syndrome (ODS) is caused by damage to the pons myelin sheat and nerve cells.

2.      Figure 1. sub categories a,b,c and d are not properly displayed, might have been cropped incorrectly during editing, kindly correct it.

3.      Few syntax errors for example

·         Line 37- … Indeed, although

·         Line 39- ….Actually, some cases of ODS associated with, for example

 

·         Line 47- ….but due to numerous

Author Response

Dear Reviewer,  Thank you very much for your review and valuable suggestions that enabled us to improve the quality of our paper. We revised the manuscript according to your suggestions, in particular:
- The language has been thoroughly corrected to eliminate typos and make the text more readable
- The image has been corrected to make the text clearer for subdivision 

Reviewer 2 Report

The paper entitled "Development of Parkinsonism in a patient with Central Pontine Myelinolysis" is well written.  The presented clinical study demonstrates the unusual clinical findings due to a complex of  multiple risk factors and pathologies and it is difficult to objectively tell the exact reason behind the parkinsonism signs. However, I believe that this case might be interesting and helpful for practicing clinicians.

I have a minor comment:

page3, line 59: Fluoxetine instead of fluoxetina

Author Response

Dear Reviewer,  Thank you very much for your review and valuable suggestions that enabled us to improve the quality of our paper. We revised the manuscript according to your suggestions, in particular, the language has been thoroughly corrected to eliminate typos and make the text more readable.