Next Article in Journal
Alteration in Transforming Growth Factor-β Receptor Expression in Gallbladder Disease: Implications of Chronic Cholelithiasis and Chronic Salmonella Typhi Infection
Previous Article in Journal
Intestinal Intussusception in An Adult Caused by Helminthic Parasitosis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Gastroenterology Insights
Volume 7
Issue 1
10.4081/gi.2016.6491
gastroent-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Gastroenterology Insights is published by MDPI from Volume 11 Issue 1 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Pseudomembranous Colitis in a Patient with Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome

by
Manuel Soria Orozco
1,*,
Eduardo Martín Nares
1,
Alvaro López Iñiguez
1,
Sandra Gónzalez Saldaña
1,
Lorena Valerdi Contreras
1 and
Jair Abdiel Toro Guerrero
2
1
Department of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico
2
Department of Pathology, Civil Hospital Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico
*
Author to whom correspondence should be addressed.
Gastroenterol. Insights 2016, 7(1), 6491; https://doi.org/10.4081/gi.2016.6491
Submission received: 2 March 2016 / Revised: 6 May 2016 / Accepted: 11 May 2016 / Published: 19 August 2016

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a hypersensitivity reaction with rash, fever and multiorgan dysfunction potentially lethal in up to 10% of cases. It often affects liver function, but it can also affect kidney, lungs, and heart. Severe gastrointestinal involvement is rare. We present a case of a 31-year-old hispanic woman with pseudomembranous colitis associated with lamotrigine-induced DRESS syndrome. To the best of our knowledge, this is the fourth reported case of severe involvement of the gastrointestinal tract and the first to report pseudomembranous colitis in the setting of DRESS syndrome.
Keywords: DRESS syndrome; multiorgan involvement; pseudomembranous colitis; lamotrigine; anticonvulsant hypersensitivity syndrome DRESS syndrome; multiorgan involvement; pseudomembranous colitis; lamotrigine; anticonvulsant hypersensitivity syndrome

Share and Cite

MDPI and ACS Style

Orozco, M.S.; Martín Nares, E.; López Iñiguez, A.; Gónzalez Saldaña, S.; Valerdi Contreras, L.; Toro Guerrero, J.A. Pseudomembranous Colitis in a Patient with Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome. Gastroenterol. Insights 2016, 7, 6491. https://doi.org/10.4081/gi.2016.6491

AMA Style

Orozco MS, Martín Nares E, López Iñiguez A, Gónzalez Saldaña S, Valerdi Contreras L, Toro Guerrero JA. Pseudomembranous Colitis in a Patient with Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome. Gastroenterology Insights. 2016; 7(1):6491. https://doi.org/10.4081/gi.2016.6491

Chicago/Turabian Style

Orozco, Manuel Soria, Eduardo Martín Nares, Alvaro López Iñiguez, Sandra Gónzalez Saldaña, Lorena Valerdi Contreras, and Jair Abdiel Toro Guerrero. 2016. "Pseudomembranous Colitis in a Patient with Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome" Gastroenterology Insights 7, no. 1: 6491. https://doi.org/10.4081/gi.2016.6491

APA Style

Orozco, M. S., Martín Nares, E., López Iñiguez, A., Gónzalez Saldaña, S., Valerdi Contreras, L., & Toro Guerrero, J. A. (2016). Pseudomembranous Colitis in a Patient with Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome. Gastroenterology Insights, 7(1), 6491. https://doi.org/10.4081/gi.2016.6491

Article Metrics

Back to TopTop