Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364
Reference
- Lee, J.; An, S.; Lee, S.-J.; Kang, J.-S. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364. [Google Scholar] [CrossRef] [PubMed]
PRMT | Method | Model | Effect on NMD Phenotype |
---|---|---|---|
General methyltransferase inhibitor | AdOx | Hela cells | Rescues nuclear import of FUS mutants (R524S, R522G, R525L) [64] |
General methyltransferase inhibitor | AdOx | Primary rat hippocampal neurons | Rescues nuclear import of FUS mutant (P525L) [64] |
General methyltransferase inhibitor | AdOx | Primary motor neurons | Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72] |
General methyltransferase inhibitor | AdOx | ALS patient-derived lymphoblastoid cells | Rescues nuclear import of FUS mutant (R518G) [73] |
PRMT1 | siRNA KD | Hela cells | Partial rescue of nuclear import of FUS mutant (P525L) [64] |
PRMT1 | KO | MEF | Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72] |
PRMT1 | siRNA KD | HEK293 | Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72] |
PRMT1 | siRNA KD | Primary motor neurons | Increases cytoplasmic FUS mutants (R521H, R521G, R521C) [72] |
PRMT1 | Inhibitor (AMI-1) | ALS patient-derived lymphoblastoid cells | Rescues nuclear import of FUS mutant (R518G) [73] |
PRMT1 | shRNA KD | Cortical neurons | Enhances neurite shortening by FUS-R521C under oxidative stress [82] |
PRMT1 | Overexpression | Cortical neurons | Prevents neurite shortening by FUS-R521C under oxidative stress [82] |
PRMT1 | Inhibitor (MS023) | NSC-34 | Abrogates PR15-induced toxicity [123] |
DART1 (PRMT1/PRMT8 ortholog) | siRNA KD | Drosophila | Enhances neurodegeneration of eyes induced by wild-type FUS or FUS-R521H [73] |
DART1 (PRMT1/PRMT8 ortholog) | siRNA KD | Drosophila | Enhances neurodegeneration of eyes induced by wild-type FUS or FUS-P525L [83] |
PRMT5 | Inhibitor (CMP5 or HLCL65) | Mouse memory T cells | Suppresses memory T cell expansion [92] |
PRMT5 | Inhibitor (CMP5) or shRNA KD | Human memory T cells | Suppresses memory T cell activation and expansion, partly through downregulation of IL-2 [92] |
PRMT5 | Inhibitor (CMP5) | OVA-induced DTH mouse | Suppresses T cell-mediated inflammatory response [92] |
PRMT5 | Inhibitor (HLCL65) | MOG-induced EAE mouse | Suppresses clinical signs of EAE through diminishing T cell-mediated inflammatory response [92] |
PRMT5 | CD4+ T-cell specific KO | MOG-induced EAE mouse | Suppresses clinical signs of EAE through diminishing T cell-mediated inflammatory response [95] |
PRMT6 | Overexpression | MN-1 | Exacerbates cytotoxicity due to polyglutamine-expanded AR [98] |
DART8 (PRMT6 ortholog) | RNAi KD | Drosophila | Suppresses neurodegenerative phenotype due to polyglutamine-expanded AR [98] |
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Lee, J.; An, S.; Lee, S.-J.; Kang, J.-S. Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364. Cells 2022, 11, 2609. https://doi.org/10.3390/cells11162609
Lee J, An S, Lee S-J, Kang J-S. Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364. Cells. 2022; 11(16):2609. https://doi.org/10.3390/cells11162609
Chicago/Turabian StyleLee, Jinwoo, Subin An, Sang-Jin Lee, and Jong-Sun Kang. 2022. "Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364" Cells 11, no. 16: 2609. https://doi.org/10.3390/cells11162609
APA StyleLee, J., An, S., Lee, S. -J., & Kang, J. -S. (2022). Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364. Cells, 11(16), 2609. https://doi.org/10.3390/cells11162609