Severity and Clinical Outcomes of Pediatric Burns—A Comprehensive Analysis of Influencing Factors
Abstract
:1. Introduction
1.1. Age and Burn Severity
- TBSA < 20%: Burns covering less than 20% of the body surface area are generally considered less severe. These burns are often treated with less intensive interventions and have lower morbidity and mortality rates.
- TBSA > 20%: Burns covering more than 20% of the body surface area are considered severe. These burns typically require more intensive medical and surgical interventions, including fluid resuscitation, extensive wound care, and possible skin grafting. The morbidity and mortality rates are significantly higher in this category.
1.2. Gender Differences
1.3. Provenance Environment and Additional Factors
1.4. Type of Burn Agent
2. Materials and Methods
2.1. Study Design
2.2. Participants
- Pediatric patients with burn injuries.
- Admission within 24 h of injury.
- Complete medical records available for review.
- Patients with non-burn-related injuries.
- Patients admitted more than 24 h post-injury.
- Incomplete medical records.
2.3. Data Collection
- Demographic Information: Age, gender, and environmental provenance (categorized as urban or rural based on the patient’s home address).
- Burn Characteristics: Type of burn agent (scald, flame, contact, chemical), total body surface area (TBSA) burned, depth of burn (categorized as superficial, partial-thickness, or full-thickness).
- Clinical Outcomes: Length of hospital stay (LOS), need for surgical intervention (e.g., debridement, skin grafting), incidence of complications (e.g., infections, scarring), and mortality.
2.4. Variables and Definitions
- Age Groups: Patients were categorized into three age groups: 0–4 years, 5–12 years, and 13–18 years.
- Gender: Male and female.
- Environmental Provenance: Urban (city area) or rural (countryside).
- Burn Agents: Classified into four categories: scalds, flames, contact burns, and chemical burns.
- Severity Indicators: TBSA, burn depth, LOS, need for surgical intervention, complications, and mortality.
2.5. Statistical Analysis
2.6. Ethical Considerations
2.7. Limitations
2.8. Quality Assurance
3. Results
3.1. Demographic Overview
3.2. Age and Burn Severity
- TBSA < 20%: 67.5% (n = 1011) of cases.
- TBSA > 20%: 32.5% (n = 487) of cases.
- The chi-square test indicated a significant association between the type of burn agent and TBSA severity (p < 0.001).
3.2.1. Infants and Toddlers (0–3 Years)
- Developmental Factors: At this stage, children are highly curious and tend to explore their environment without understanding potential dangers. Their limited motor skills and coordination make them more prone to accidents.
- Common Burn Agents: Scald injuries were particularly prevalent in this age group, often resulting from hot liquids such as boiling water, soups, and hot beverages. Young children are often at the height where they can reach for items on tables or stoves, leading to accidental spills.
- Lack of Supervision: Infants and toddlers require constant supervision. Even brief moments of inattention can result in significant injuries, such as when a child pulls down a hot kettle or touches a hot appliance.
3.2.2. Preschool and Early School Age (4–7 Years)
- Increased Mobility and Curiosity: While these children have better motor skills and some understanding of danger, their curiosity and desire to explore remain high. This age group is more likely to suffer from contact burns due to touching hot surfaces or objects.
- Parental Education and Safety Measures: The implementation of safety measures, such as installing guards on stoves and keeping hot liquids out of reach, can significantly reduce the incidence of burns. Parental education plays a crucial role in preventing injuries in this age group.
- Severity of Burns: The burns in this age group were less severe than in infants and toddlers, with a lower percentage of TBSA affected. However, significant injuries still occurred, particularly from hot liquids and contact with hot surfaces.
3.2.3. Older Children (8–12 Years)
- Independence and Risk-Taking Behavior: As children grow older, they gain more independence and may engage in activities without adult supervision. This age group is more likely to experiment with fire, fireworks, and other hazardous activities, leading to a higher incidence of flame burns.
- Outdoor Activities: Engagement in outdoor activities, such as camping or playing with firecrackers, increases the risk of flame burns. Boys, in particular, are more prone to such activities, resulting in more severe injuries.
- Severity and TBSA: Although less frequent than in younger age groups, the burns in older children were often more severe due to the nature of the burn agents involved. Flame burns typically affected a larger TBSA, requiring extensive medical interventions such as debridement and skin grafting.
3.2.4. Adolescents (13–18 Years)
- Behavioral Factors: This age group is characterized by increased autonomy, risk-taking behavior, and peer influence. Adolescents may engage in activities that pose significant burn risks, such as handling flammable substances, participating in bonfires, or using fireworks.
- Burn Agents: Flame burns and chemical burns were more common in this age group. Adolescents are more likely to be involved in accidents involving gasoline, fireworks, and other flammable materials. Chemical burns may result from exposure to substances used in experiments or industrial settings.
- Severity and TBSA: The burns in adolescents tended to be severe, with a higher TBSA affected compared to younger children. Flame burns, in particular, were associated with significant morbidity and required complex medical management, including surgical interventions.
3.3. Gender Differences
- Odds Ratio (OR): 1.25
- 95% Confidence Interval (CI): 1.01–1.55
3.4. Prevalence of Flame Burns
- Risk-Taking Behaviors: Boys are generally more likely to engage in behaviors that expose them to higher risks of burns, such as playing with fire, fireworks, and engaging in outdoor activities like camping and bonfires. These activities inherently carry a higher risk of flame burns.
- Curiosity and Experimentation: Boys often display greater curiosity towards experimenting with fire and flammable substances. This can lead to accidents involving matches, lighters, and other ignition sources.
- Physical Activities: Engaging in physical activities and sports that might involve fire or heat elements, such as grilling or participating in scout activities, further increases their exposure to potential burn hazards.
3.5. Severity of Burns
- Higher Risk Exposure: The nature of the activities that boys engage in tends to result in larger and more severe burns. For example, accidents involving gasoline or other accelerants can lead to extensive flame burns covering large body areas.
- Greater Mobility and Outdoor Play: Boys often spend more time outdoors and are more physically active, leading to increased exposure to environmental hazards that can cause severe burns. This includes not only direct contact with fire but also burns from sun exposure and hot surfaces.
- Delayed Medical Attention: In some cases, boys may not immediately report injuries or seek medical help, potentially leading to more severe outcomes. The time delay in receiving proper medical treatment can exacerbate the severity of burns.
3.6. Psychological and Social Factors
- Social Norms and Expectations: Societal expectations and norms often encourage boys to engage in more daring and adventurous activities, sometimes at the expense of safety. This cultural aspect can contribute to the higher incidence of severe burns.
- Parental Supervision and Education: There may be differences in how boys and girls are supervised and educated about safety. Boys might receive less stringent supervision in activities perceived as masculine or adventurous, increasing their risk of burns.
3.7. Provenance Environment
- Socioeconomic Status (Lower SES vs. Higher SES):Odds Ratio (OR): 1.6895% Confidence Interval (CI): 1.30–2.17p-value: <0.001Interpretation: Children from lower socioeconomic status backgrounds are 1.68 times more likely to suffer severe burns compared to those from higher SES backgrounds. This finding is highly significant (p < 0.001), highlighting socioeconomic status as a critical factor in burn severity.
3.8. Prevalence and Severity of Burns in Rural Areas
- Delayed Medical Intervention: One of the primary reasons for the increased severity of burns in rural areas is the delay in receiving medical treatment. Geographic isolation often means that rural patients have to travel longer distances to reach healthcare facilities. This delay can exacerbate the severity of burns, as prompt medical intervention is crucial in preventing complications and reducing the extent of the injury.
- Limited Access to Specialized Burn Care: Rural areas typically lack specialized burn care facilities. This limitation forces initial treatment to be carried out in general healthcare settings that may not be equipped with the necessary resources or expertise to handle severe burn cases effectively. As a result, children in rural areas may not receive the optimal level of care required to manage severe burns promptly and adequately.
- Emergency Response and Infrastructure: The emergency response infrastructure in rural areas is often less developed than in urban settings. Limited availability of emergency medical services (EMSs) and longer response times can contribute to the higher severity of burns. Additionally, rural healthcare providers might have limited training in advanced burn care, impacting the quality of initial treatment.
3.9. Contributing Factors in Rural Settings
- Socioeconomic Constraints: Rural areas frequently face socioeconomic challenges, including lower income levels and higher rates of poverty. These constraints can limit the ability of families to implement safety measures in their homes, such as installing smoke detectors or maintaining safe cooking practices. Economic hardships can also impact the timely seeking of medical care.
- Educational Gaps: Lower levels of education among rural populations can contribute to a lack of awareness about burn prevention and first aid. Parents and caregivers might be less informed about safety practices and the immediate steps to take following a burn injury, resulting in delayed and inadequate initial care.
- Household Practices: Rural households often rely on traditional cooking methods, such as open flames and wood stoves, which increase the risk of severe burns. Additionally, the use of kerosene lamps and other hazardous fuels in poorly ventilated environments can lead to accidents that result in severe burns.
3.10. Urban Environment Insights
- Proximity to Healthcare Facilities: Urban settings typically offer closer proximity to healthcare facilities, including specialized burn centers. Quick access to medical care allows for timely and effective treatment, reducing the severity of burns.
- Advanced Medical Infrastructure: Urban healthcare facilities are more likely to be equipped with the latest medical technologies and staffed by specialists trained in burn care. This advanced infrastructure enables comprehensive treatment plans that can better manage and mitigate the impact of severe burns.
- Enhanced Emergency Services: Urban areas benefit from well-developed emergency services with faster response times. The availability of EMSs and well-coordinated hospital transfer systems ensures that burn patients receive prompt and appropriate care.
3.11. Implications for Intervention and Policy
- Improving Access to Care: Establishing more burn care facilities in rural regions and enhancing transportation networks to ensure timely access to existing specialized centers can mitigate the delays in treatment. Telemedicine could also play a crucial role in providing immediate expert consultation and guiding initial care.
- Educational Programs: Implementing educational campaigns focused on burn prevention and first aid can raise awareness and improve the response to burn injuries. Training programs for rural healthcare providers can enhance their skills in managing burn cases effectively.
- Socioeconomic Support: Providing financial assistance and resources to low-income families in rural areas can enable them to adopt safer household practices and access medical care without delay. Subsidies for safety equipment like smoke detectors and fire extinguishers can also be beneficial.
3.12. Type of Burn Agent
3.13. Flame Burns
- Flame Burns (vs. Scalds):Odds Ratio (OR): 2.3095% Confidence Interval (CI): 1.75–3.02p-value: <0.001Interpretation: Children with flame burns are 2.30 times more likely to have severe burns compared to those with scald injuries. This result is highly significant (p < 0.001), emphasizing the greater severity associated with flame burns.
- Severity and TBSA: Flame burns had an average Total Body Surface Area (TBSA) of 25%, indicating the extensive nature of these injuries. The high TBSA reflects the ability of flames to spread rapidly and affect multiple body regions.
- Clinical Management: The severity of flame burns often necessitates extensive surgical interventions, including debridement (removal of dead tissue) and skin grafting (transplantation of healthy skin to cover the burn wound). These procedures are critical for preventing infection, promoting healing, and improving functional and cosmetic outcomes.
- Common Causes: Flame burns in children are frequently caused by accidents involving open flames, such as those from candles, fireplaces, campfires, and fireworks. Mishandling of flammable substances like gasoline can also result in severe flame burns.
- Implications for Care: Due to their severity, flame burns require immediate and comprehensive medical care, often in specialized burn centers. Long-term rehabilitation and psychological support are also essential components of the recovery process.
3.14. Scald Burns
- Severity and TBSA: Scald burns presented with an average TBSA of 18%. While this is lower than that of flame burns, the extent of injury can still be considerable, particularly in younger children who have smaller body surfaces.
- Clinical Management: Treatments for scald burns include wound care, pain management, and sometimes surgical intervention. In severe cases, skin grafting may be necessary to cover areas where the skin has been extensively damaged.
- Common Causes: Common sources of scald burns include hot water, soups, hot beverages, and steam from cooking. Young children are particularly vulnerable as they may accidentally pull hot liquids onto themselves.
- Implications for Care: Prevention strategies, such as educating parents and caregivers about kitchen safety and the importance of keeping hot liquids out of reach, are crucial. Prompt medical intervention can mitigate complications and promote faster healing.
3.15. Contact Burns
- Contact Burns (vs. Scalds):Odds Ratio (OR): 1.2095% Confidence Interval (CI): 0.85–1.68p-value: 0.30Interpretation: The likelihood of severe burns from contact burns is not significantly different from scalds (p = 0.30), suggesting no significant impact on burn severity.
- Severity and TBSA: Contact burns had an average TBSA of 12%. Although typically affecting smaller areas, these burns can still cause deep tissue damage and significant pain.
- Clinical Management: The treatment of contact burns involves immediate cooling of the burn area, wound care, and pain management. In cases where the burn penetrates deeper layers of skin, surgical intervention may be required.
- Common Causes: Common causes include touching hot surfaces such as stoves, irons, and heating appliances. Younger children are at higher risk due to their exploratory behavior and lack of awareness of danger.
- Implications for Care: Educating families about the dangers of leaving hot objects within reach of children and implementing safety measures, such as stove guards, can prevent many contact burns.
3.16. Chemical Burns
- Chemical Burns (vs. Scalds):Odds Ratio (OR): 1.7595% Confidence Interval (CI): 1.05–2.90p-value: 0.032Interpretation: Chemical burns increase the odds of severe burns by 1.75 times compared to scalds, with the association being statistically significant (p = 0.032).
- Severity and TBSA: Chemical burns accounted for 5% of cases but resulted in significant morbidity. These burns can penetrate deeper into tissues than thermal burns, causing extensive damage.
- Clinical Management: Immediate and thorough irrigation of the affected area to remove the chemical agent is crucial. Long-term care often involves wound management, pain control, and possibly surgical intervention. Specific treatments depend on the type of chemical involved.
- Common Causes: Chemical burns can result from exposure to household cleaners, industrial chemicals, and certain school laboratory substances. Proper storage and handling of chemicals are essential to prevent these injuries.
- Implications for Care: Awareness and education about the risks of chemicals, appropriate safety measures, and first aid responses are vital. Health professionals must be trained to manage the specific challenges associated with chemical burns.
3.17. Additional Factors
3.18. Socioeconomic Status (SES)
- Socioeconomic Status (Lower SES vs. Higher SES):Odds Ratio (OR): 1.6895% Confidence Interval (CI): 1.30–2.17p-value: <0.001Interpretation: Children from lower socioeconomic status backgrounds are 1.68 times more likely to suffer severe burns compared to those from higher SES backgrounds. This finding is highly significant (p < 0.001), highlighting socioeconomic status as a critical factor in burn severity.
- Severity and TBSA: Children from lower SES backgrounds exhibited a higher mean Total Body Surface Area (TBSA) of 22%, compared to 15% in their higher SES counterparts (p < 0.05). This significant difference underscores the impact of socioeconomic factors on the risk and extent of burn injuries. These findings are included in Figure 4 and for better visualization we used blue for low socioeconomic status, orange for medium socioeconomic status, and green for high socioeconomic status.
- Contributing Factors:Housing Conditions: Families with lower SES often live in housing conditions that increase the risk of burns. These may include overcrowded living spaces, inadequate heating systems, and the use of unsafe cooking methods such as open flames or faulty electrical appliances.Access to Safety Measures: Lower SES families might lack the financial resources to implement safety measures such as smoke detectors, fire extinguishers, and safe cooking equipment. Additionally, they may not afford regular maintenance and safety checks for electrical appliances and heating systems.Healthcare Access: Limited access to healthcare services can delay the treatment of burns, exacerbating their severity. Lower SES families may also face barriers such as lack of insurance, transportation issues, and limited availability of specialized care, leading to more severe outcomes.
3.19. Parental Education Level
- Severity of Burns: Lower parental education levels were associated with more severe burns. Parents with limited education might lack awareness of burn risks and prevention strategies, leading to higher rates of severe burn incidents.
- Hospital Stays: The data indicated that children with less-educated parents experienced prolonged hospital stays. This can be attributed to delays in seeking treatment, inadequate initial first aid, and potentially poorer compliance with post-discharge care instructions due to limited health literacy.
- Awareness and Prevention: Educated parents are more likely to be aware of and implement effective burn prevention measures, such as supervising children closely, using safety devices in the home, and educating their children about fire hazards. They are also more likely to know the proper first aid steps to take immediately after a burn injury, reducing the severity of the burn and the need for extensive medical treatment.
3.20. Clinical Outcomes
Length of Hospital Stay (LOS)
3.21. Need for Surgical Intervention
3.22. Incidence of Complications
- Infections (15%): Infections were the most prevalent complication, significantly impacting patient recovery. The incidence of infections was notably higher in patients with a Total Body Surface Area (TBSA) greater than 20%. This is likely due to the larger wound surface area providing a greater opportunity for bacterial colonization and infection. Additionally, patients from lower socioeconomic backgrounds were more susceptible to infections, potentially due to limited access to early and adequate wound care, poor living conditions, and nutritional deficiencies that could impair immune function.
- Significant Scarring (10%): Scarring is a common outcome of burn injuries, often leading to functional and aesthetic concerns. Significant scarring was observed in 10% of the cases, affecting both the physical and psychological well-being of the patients. The severity of scarring can be influenced by the depth and extent of the burn, the promptness and effectiveness of initial treatment, and the patient’s overall health and nutritional status.
- Contractures (3%): Contractures, which involve the tightening of skin and underlying tissues, were observed in 3% of the cases. These often result in restricted movement and require surgical interventions such as skin grafting or physiotherapy for correction. Contractures are more common in deeper burns and areas over joints, highlighting the importance of early and aggressive management to prevent these debilitating complications.
3.23. Mortality Rate Analysis
- Physiological Factors: Younger children have thinner skin, making them more susceptible to deeper burns. Additionally, their immature immune systems are less equipped to handle the severe stress and potential infections that can accompany major burns.
- Developmental Factors: At this age, children are naturally curious and have limited awareness of dangers, making them more prone to accidents involving burns.
- Rural vs. Urban Mortality Rates: The study found that delays in receiving specialized burn care, particularly in rural areas, were a major contributing factor to the higher mortality rates observed in these regions. Patients from rural areas often face longer transportation times to reach advanced medical facilities and may lack immediate access to critical care during the initial post-injury period.
- Socioeconomic Status: Lower socioeconomic status was associated with higher mortality rates, reflecting disparities in access to healthcare resources, preventive measures, and timely medical intervention. Families with limited financial means may also face challenges in adhering to follow-up care and rehabilitation protocols, further exacerbating outcomes.
4. Discussion
4.1. Overview
4.2. Age and Burn Severity
4.3. Gender Differences
4.4. Provenance Environment
4.5. Type of Burn Agent
4.6. Socioeconomic Status (SES)
4.7. Parental Education Level
4.8. Length of Hospital Stay (LOS)
4.9. Surgical Interventions
4.10. Complications
4.11. Mortality
4.12. Implications for Practice and Policy
- Targeted Prevention Strategies: Educational campaigns should be tailored to address the specific risks associated with different age groups, genders, and living environments. For example, programs focusing on kitchen safety and the dangers of hot liquids can significantly reduce scald injuries among young children. Additionally, promoting safe play and risk-averse behaviors in boys could reduce the incidence of severe flame burns.
- Improving Access to Care: Enhancing healthcare infrastructure in rural areas is crucial. This includes establishing more burn care facilities, improving transportation networks for quicker access to care, and utilizing telemedicine to provide expert consultations in remote regions. Ensuring that rural populations have timely access to advanced burn care can significantly reduce the severity and complications of burn injuries.
- Educational Programs: Implementing educational programs for parents, particularly those with lower education levels, can raise awareness about burn prevention and first aid. These programs should be accessible and culturally sensitive to effectively reach diverse populations. By educating parents on the importance of home safety measures and proper burn care, the incidence and severity of pediatric burns can be reduced.
- Socioeconomic Support: Policies aimed at improving the living conditions of lower SES families can mitigate the risk of burn injuries. This includes providing financial assistance for safety devices, home improvements, and ensuring affordable access to healthcare services. Addressing the socioeconomic determinants of health can lead to a significant reduction in burn-related morbidity and mortality.
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
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Demographic and Burn Characteristics | Cases |
---|---|
Number of cases | 1498 |
Mean Age (years) | 5.8 |
Gender (Male) (%) | 54 |
Scalds (%) | 45 |
Flame Burns (%) | 30 |
Contact Burns (%) | 15 |
Chemical Burns (%) | 5 |
TBSA < 20% (%) | 67.5 |
TBSA > 20% (%) | 32.5 |
Surgical interventions required (%) | 62.5 |
Mean length of Hospital Stay (days) | 11.25 |
Incidence of Infections (%) | 17.5 |
Incidence of Significant Scarring (%) | 11 |
Incidence of Contractures (%) | 3.5 |
Mortality Rate (%) | 2.5 |
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Toma, A.; Voicu, D.; Popazu, C.; Mihalache, D.; Duca, O.; Dănilă, D.M.; Enescu, D.M. Severity and Clinical Outcomes of Pediatric Burns—A Comprehensive Analysis of Influencing Factors. J. Pers. Med. 2024, 14, 788. https://doi.org/10.3390/jpm14080788
Toma A, Voicu D, Popazu C, Mihalache D, Duca O, Dănilă DM, Enescu DM. Severity and Clinical Outcomes of Pediatric Burns—A Comprehensive Analysis of Influencing Factors. Journal of Personalized Medicine. 2024; 14(8):788. https://doi.org/10.3390/jpm14080788
Chicago/Turabian StyleToma, Alexandra, Dragoș Voicu, Constantin Popazu, Daniela Mihalache, Oana Duca, Dumitru Marius Dănilă, and Dan Mircea Enescu. 2024. "Severity and Clinical Outcomes of Pediatric Burns—A Comprehensive Analysis of Influencing Factors" Journal of Personalized Medicine 14, no. 8: 788. https://doi.org/10.3390/jpm14080788
APA StyleToma, A., Voicu, D., Popazu, C., Mihalache, D., Duca, O., Dănilă, D. M., & Enescu, D. M. (2024). Severity and Clinical Outcomes of Pediatric Burns—A Comprehensive Analysis of Influencing Factors. Journal of Personalized Medicine, 14(8), 788. https://doi.org/10.3390/jpm14080788