Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer

Zhong, Jeffrey; Trinh, Ilene; Raju, Shine; Hsu, Melinda

doi:10.3390/jcm14030770

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Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer

¹

Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA

²

Department of Pulmonary, Critical Care, and Sleep Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA

³

Department of Hematology and Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA

^*

Author to whom correspondence should be addressed.

J. Clin. Med. 2025, 14(3), 770; https://doi.org/10.3390/jcm14030770

Submission received: 19 December 2024 / Revised: 18 January 2025 / Accepted: 23 January 2025 / Published: 24 January 2025

(This article belongs to the Special Issue Early-Stage and Operable Non-Small Cell Lung Cancer Treatment: Current Practice and Future Perspectives)

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Abstract

Lung cancer is the leading cause of cancer-related death worldwide, and patients with operable early-stage NSCLC are typically managed surgically. While effective, surgical resection can significantly impact pulmonary function and quality of life. Pulmonary rehabilitation (PR) is a comprehensive, multimodal approach that is an established cornerstone in the treatment of COPD. It has similarly demonstrated multiple benefits in patients with lung cancer who have undergone lobectomy or resection by improving pulmonary function, increasing exercise tolerance, improving nutritional status, providing psychological support, and enhancing quality of life. Despite this, PR for early-stage operable NSCLC is oftentimes not standardized, and challenges to adherence remain. In this review, we examine the components of PR, the role of PR in pre- and postoperative settings in patients with early-stage NSCLC, implementation strategies for PR, and future directions and challenges of PR in operable NSCLC.

Keywords: pulmonary rehabilitation; lung cancer survivorship

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MDPI and ACS Style

Zhong, J.; Trinh, I.; Raju, S.; Hsu, M. Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer. J. Clin. Med. 2025, 14, 770. https://doi.org/10.3390/jcm14030770

AMA Style

Zhong J, Trinh I, Raju S, Hsu M. Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer. Journal of Clinical Medicine. 2025; 14(3):770. https://doi.org/10.3390/jcm14030770

Chicago/Turabian Style

Zhong, Jeffrey, Ilene Trinh, Shine Raju, and Melinda Hsu. 2025. "Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer" Journal of Clinical Medicine 14, no. 3: 770. https://doi.org/10.3390/jcm14030770

APA Style

Zhong, J., Trinh, I., Raju, S., & Hsu, M. (2025). Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer. Journal of Clinical Medicine, 14(3), 770. https://doi.org/10.3390/jcm14030770

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer

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