Next Article in Journal
Colorimetric and Atomic Absorption Spectrometric Methods for the Determination of Hyoscine N-Butylbromide in Pharmaceutical Formulations Using Cobalt (II) and Chromium (III) Thiocyanate Complexes
Previous Article in Journal
Chemical composition and antibacterial activities of the essential oils of Plectranthus glandulosus and Cinnumomum zeylrrnicum from Cameroon
 
 
Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Phenylpropanoids and Polyacetylenes from Ligusticum mutellina (Apiaceae) of Tyrolean Origin

by
Spitaler Renate
1,
Ellmerer-Müller Ernst-Peter
2,
Zidorn Christian
2,* and
Stuppner Hermann
1
1
Institut für Phannazie, Abteilung Pharmakognosie, Leopold-Franzens-Universität Innsbruck, Innrain 52, A-6020 Innsbruck, Austria
2
Institut für Organische Chemie, Leopold-Franzens-Universität Innsbruck, Innrain 52a, A-6020 Innsbruck, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2002, 70(1), 101-109; https://doi.org/10.3797/scipharm.aut-02-12
Submission received: 3 February 2002 / Revised: 27 February 2002 / Accepted: 27 February 2002 / Published: 25 March 2002

Abstract

Roots of Ligusticum mutellina (L.) CRANTZ afforded five major compounds, the phenylpropanoids trans-isoelemicin (1), sarisan (2), and trans-isomyristicin (3), and the polyacetylenes falcarindiol (4) and falcarindiol-3-O-acetate (5). Structures were assigned by 1D- and 2D-NMR spectroscopy. Close inspection of the NMR spectra of falcarindiol-3-O-acetate (5) and comparison with the literature revealed that published NMR data for this compound are most probably attributable to cis or trans Δ2-isofalcarindiol-1-O-acetate (6a/6b). 1H and 13C NMR data for falcarindiol-3-O-acetate are given and trans-isoelemicin (1), sarisan (2), and trans-isomyristicin (3), falcarindiol (4), and falcarindiol-3-O-acetate (5) are reported for the first time from Ligusticum mutellina. Chemosystematic and ethnopharmacological implications of the findings are discussed briefly.
Keywords: Apiaceae, Ligusticum, Phenylpropanoids, Polyacetylenes, Falcarindiol-3-O-acetate Apiaceae, Ligusticum, Phenylpropanoids, Polyacetylenes, Falcarindiol-3-O-acetate

Share and Cite

MDPI and ACS Style

Renate, S.; Ernst-Peter, E.-M.; Christian, Z.; Hermann, S. Phenylpropanoids and Polyacetylenes from Ligusticum mutellina (Apiaceae) of Tyrolean Origin. Sci. Pharm. 2002, 70, 101-109. https://doi.org/10.3797/scipharm.aut-02-12

AMA Style

Renate S, Ernst-Peter E-M, Christian Z, Hermann S. Phenylpropanoids and Polyacetylenes from Ligusticum mutellina (Apiaceae) of Tyrolean Origin. Scientia Pharmaceutica. 2002; 70(1):101-109. https://doi.org/10.3797/scipharm.aut-02-12

Chicago/Turabian Style

Renate, Spitaler, Ellmerer-Müller Ernst-Peter, Zidorn Christian, and Stuppner Hermann. 2002. "Phenylpropanoids and Polyacetylenes from Ligusticum mutellina (Apiaceae) of Tyrolean Origin" Scientia Pharmaceutica 70, no. 1: 101-109. https://doi.org/10.3797/scipharm.aut-02-12

APA Style

Renate, S., Ernst-Peter, E. -M., Christian, Z., & Hermann, S. (2002). Phenylpropanoids and Polyacetylenes from Ligusticum mutellina (Apiaceae) of Tyrolean Origin. Scientia Pharmaceutica, 70(1), 101-109. https://doi.org/10.3797/scipharm.aut-02-12

Article Metrics

Back to TopTop