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Sci. Pharm.
Volume 82
Issue 1
10.3797/scipharm.1307-08
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Short Communication

HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells

by
Koffi Marcel KONAN
1,
Janat Akhanovna MAMYRBEKOVA-BEKRO
1,
Norbert BAKALARA
2,3,
David VIRIEUX
3,
Jean-Luc PIRAT
3 and
Yves-Alain BEKRO
1,*
1
Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire
2
UMR 5253, ICG Montpellier, Equipe AM2N, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier cedex 5, France
3
INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2014, 82(1), 171-176; https://doi.org/10.3797/scipharm.1307-08
Submission received: 9 July 2013 / Accepted: 19 November 2013 / Published: 19 November 2013
Versions Notes

Abstract

The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC50 > 1 mg/ml).
Keywords: Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells

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MDPI and ACS Style

KONAN, K.M.; MAMYRBEKOVA-BEKRO, J.A.; BAKALARA, N.; VIRIEUX, D.; PIRAT, J.-L.; BEKRO, Y.-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Sci. Pharm. 2014, 82, 171-176. https://doi.org/10.3797/scipharm.1307-08

AMA Style

KONAN KM, MAMYRBEKOVA-BEKRO JA, BAKALARA N, VIRIEUX D, PIRAT J-L, BEKRO Y-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Scientia Pharmaceutica. 2014; 82(1):171-176. https://doi.org/10.3797/scipharm.1307-08

Chicago/Turabian Style

KONAN, Koffi Marcel, Janat Akhanovna MAMYRBEKOVA-BEKRO, Norbert BAKALARA, David VIRIEUX, Jean-Luc PIRAT, and Yves-Alain BEKRO. 2014. "HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells" Scientia Pharmaceutica 82, no. 1: 171-176. https://doi.org/10.3797/scipharm.1307-08

APA Style

KONAN, K. M., MAMYRBEKOVA-BEKRO, J. A., BAKALARA, N., VIRIEUX, D., PIRAT, J. -L., & BEKRO, Y. -A. (2014). HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Scientia Pharmaceutica, 82(1), 171-176. https://doi.org/10.3797/scipharm.1307-08

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