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Correction to Biomedicines 2020, 8(7), 217.
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Correction

Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217

by
Isha Sharma
,
Fei Deng
and
Yashpal S. Kanwar
*
Department of Pathology, Northwestern University, Chicago, IL 60611, USA
*
Author to whom correspondence should be addressed.
Biomedicines 2024, 12(11), 2610; https://doi.org/10.3390/biomedicines12112610
Submission received: 22 November 2023 / Accepted: 31 October 2024 / Published: 15 November 2024
(This article belongs to the Special Issue Regenerative Medicine in Diabetes)
Browse Figure
Versions Notes
In the original publication [1], there was a mistake in Figure 3 in the published version. Figure 3G got duplicated while assembling Figure 3. The corrected Figure 3 is shown below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Sharma, I.; Deng, F.; Kanwar, Y.S. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217. [Google Scholar] [CrossRef] [PubMed]
Biomedicines 12 02610 g003
Figure 3. Modulation of expression of sirtuins and transcription factors (PGC-1α and YY-1) by MIOX. Panels (A,B): immunoblotting data indicated a decreased expression of Sirt1, Sirt3 and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and Ying-Yang1 (YY-1) following HFD administration in various strains of mice. The most notable reduction was seen in MIOX-TG mice prior to and following HFD treatment. The ob/ob mice also had reduced expression, and it was considerably restored in ob/MIOXKO mice. Panels (C–H): immunofluorescence microscopy revealed reduced expression of YY-1 in HK-2 cells (proximal tubular cell line) transfected with MIOX pcDNA, which was further decreased following treatment with palmitate-BSA (P-BSA). The exposure of MIOX-siRNA to P-BSA-treated HK-2 cells partially restored the expression of YY-1 (magnification: 200×). Panel (I): Western blot data indicated the changes in the expression of MIOX and Sirt1, which basically recapitulated the changes observed in YY-1 transcription factor in HK-2 cells after various treatments.
Figure 3. Modulation of expression of sirtuins and transcription factors (PGC-1α and YY-1) by MIOX. Panels (A,B): immunoblotting data indicated a decreased expression of Sirt1, Sirt3 and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and Ying-Yang1 (YY-1) following HFD administration in various strains of mice. The most notable reduction was seen in MIOX-TG mice prior to and following HFD treatment. The ob/ob mice also had reduced expression, and it was considerably restored in ob/MIOXKO mice. Panels (C–H): immunofluorescence microscopy revealed reduced expression of YY-1 in HK-2 cells (proximal tubular cell line) transfected with MIOX pcDNA, which was further decreased following treatment with palmitate-BSA (P-BSA). The exposure of MIOX-siRNA to P-BSA-treated HK-2 cells partially restored the expression of YY-1 (magnification: 200×). Panel (I): Western blot data indicated the changes in the expression of MIOX and Sirt1, which basically recapitulated the changes observed in YY-1 transcription factor in HK-2 cells after various treatments.
Biomedicines 12 02610 g003
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MDPI and ACS Style

Sharma, I.; Deng, F.; Kanwar, Y.S. Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217. Biomedicines 2024, 12, 2610. https://doi.org/10.3390/biomedicines12112610

AMA Style

Sharma I, Deng F, Kanwar YS. Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217. Biomedicines. 2024; 12(11):2610. https://doi.org/10.3390/biomedicines12112610

Chicago/Turabian Style

Sharma, Isha, Fei Deng, and Yashpal S. Kanwar. 2024. "Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217" Biomedicines 12, no. 11: 2610. https://doi.org/10.3390/biomedicines12112610

APA Style

Sharma, I., Deng, F., & Kanwar, Y. S. (2024). Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8, 217. Biomedicines, 12(11), 2610. https://doi.org/10.3390/biomedicines12112610

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