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Volume 11
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Journal of Mind and Medical Sciences is published by MDPI from Volume 12 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Valparaiso University (ValpoScholar).
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Article

Efficacy of Tranexamic Acid in Nasopharyngeal Hemorrhage; Single Center Prospective Study and Literature Review

by
Septar Haldun
1,
Andra-Iulia Suceveanu
2,
Mihai Lupascu
1,*,
Laura Mazilu
3,
Alina Nicoara
4,
Viorel Gherghina
5,
Felix Voinea
6,
Razvan Hainarosie
7,
Alexandru Aristide Alexe
1,
Ana Maria Dascalu
8 and
Adrian Paul Suceveanu
2
1
Department of Otorhynolaryngology, Faculty of Medicine, Ovidius University, Universității AVE, Constanta, Romania
2
Department of Gastroenterology, Faculty of Medicine, Ovidius University, Constanta, Romania
3
Department of Oncology, Faculty of Medicine, Ovidius University, Constanta, Romania
4
Department of Internal Medicine, Faculty of Medicine, Ovidius University, Constanta, Romania
5
Department of Intensive Care, Faculty of Medicine, Ovidius University, Constanta, Romania
6
Department of Urology, Faculty of Medicine, Ovidius University, Constanta, Romania
7
Department of Otorhynolaryngology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
8
Department of Ophthalmology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
*
Author to whom correspondence should be addressed.
J. Mind Med. Sci. 2024, 11(1), 189-194; https://doi.org/10.22543/2392-7674.1469
Submission received: 7 January 2024 / Revised: 7 February 2024 / Accepted: 11 March 2024 / Published: 30 April 2024

Abstract

Nasopharyngeal hemorrhage is one of the most common ear, nose, and throat (ENT) emergencies that present in a hospital or primary care clinic. While many cases of hemorrhage are self-limiting, in more severe cases medical intervention is necessary, either to cauterize the bleeding vessel or to pack the nose with various materials (thus involving specialized medical care and time, which implicitly lead to additional costs). In the case of the packaging, the medical treatment can in some cases be extremely painful and unpleasant. Tranexamic acid is an affordable, inexpensive, easy-to-use antifibrinolytic agent and with no notable side effects, as demonstrated by numerous studies related to most surgical fields. The aim of this paper is to provide an evidence-based approach to the use of tranexamic acid (TXA) in nasopharyngeal hemorrhages in our research center, comparing with the available literature on the subject, but presented in an updated form. As a conclusion, the combined use (intravenous and topical) of TXA may be a reasonable, safe and non-invasive option for hemodynamic stabilization of rhino-pharyngeal bleeding.
Keywords: tranexamic acid; Rhino-Pharyngeal; hemorrhage tranexamic acid; Rhino-Pharyngeal; hemorrhage

Share and Cite

MDPI and ACS Style

Haldun, S.; Suceveanu, A.-I.; Lupascu, M.; Mazilu, L.; Nicoara, A.; Gherghina, V.; Voinea, F.; Hainarosie, R.; Alexe, A.A.; Dascalu, A.M.; et al. Efficacy of Tranexamic Acid in Nasopharyngeal Hemorrhage; Single Center Prospective Study and Literature Review. J. Mind Med. Sci. 2024, 11, 189-194. https://doi.org/10.22543/2392-7674.1469

AMA Style

Haldun S, Suceveanu A-I, Lupascu M, Mazilu L, Nicoara A, Gherghina V, Voinea F, Hainarosie R, Alexe AA, Dascalu AM, et al. Efficacy of Tranexamic Acid in Nasopharyngeal Hemorrhage; Single Center Prospective Study and Literature Review. Journal of Mind and Medical Sciences. 2024; 11(1):189-194. https://doi.org/10.22543/2392-7674.1469

Chicago/Turabian Style

Haldun, Septar, Andra-Iulia Suceveanu, Mihai Lupascu, Laura Mazilu, Alina Nicoara, Viorel Gherghina, Felix Voinea, Razvan Hainarosie, Alexandru Aristide Alexe, Ana Maria Dascalu, and et al. 2024. "Efficacy of Tranexamic Acid in Nasopharyngeal Hemorrhage; Single Center Prospective Study and Literature Review" Journal of Mind and Medical Sciences 11, no. 1: 189-194. https://doi.org/10.22543/2392-7674.1469

APA Style

Haldun, S., Suceveanu, A.-I., Lupascu, M., Mazilu, L., Nicoara, A., Gherghina, V., Voinea, F., Hainarosie, R., Alexe, A. A., Dascalu, A. M., & Suceveanu, A. P. (2024). Efficacy of Tranexamic Acid in Nasopharyngeal Hemorrhage; Single Center Prospective Study and Literature Review. Journal of Mind and Medical Sciences, 11(1), 189-194. https://doi.org/10.22543/2392-7674.1469

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