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Journal of Mind and Medical Sciences is published by MDPI from Volume 12 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Valparaiso University (ValpoScholar).
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Review

Helicobacter pylori: Types of Diseases, Diagnosis, Treatment and Causes of Therapeutic Failure

by
Cosmin Vasile Obleaga
1,*,
Cristin Constantin Vere
2,
Ionica Daniel Valcea
1,
Mihai Calin Ciorbagiu
1,
Emil Moraru
1 and
Cecil Sorin Mirea
1
1
Department of Surgery, Craiova University of Medicine and Pharmacy, Craiova, Romania
2
Department of Gastroenterology, Craiova University of Medicine and Pharmacy, Craiova, Romania
*
Author to whom correspondence should be addressed.
J. Mind Med. Sci. 2016, 3(2), 150-161; https://doi.org/10.22543/2392-7674.1048
Submission received: 31 July 2016 / Revised: 31 August 2016 / Accepted: 20 September 2016 / Published: 24 September 2016

Abstract

Acute upper gastrointestinal lesions have a multifactorial etiology but, regardless of the cause, they are related to mucosal barrier destruction. Since Helicobacter pylori induces a superficial chronic gastritis with the infiltration of neutrophils in the mucosa, it was speculated that Helicobacter pylori infection could also cause bleeding lesions. The diagnosis, the proper treatment and the revaluation of its effectiveness actually represent the prophylaxis of some diseases such as peptic ulcer, gastric lymphoma or mucosa-associated lymphoid tissue (MALT) and gastric cancer. These diseases and their severe complications are life-threatening for the patient. Periodic renewal of the treatment and knowing the real causes of Helicobacter pylori resistance to various antibiotics must always be understood by the clinician. Although Helicobacter pylori treatment fails in about 20% of cases, moral support of the patient by the clinician, information about possible evolutional complications of Helicobacter pylori infection, and periodic evaluation of the patient during therapy, are important tools on which the therapeutic success depends.
Keywords: helicobacter pylori; diagnosis; bleeding; treatment resistance helicobacter pylori; diagnosis; bleeding; treatment resistance

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MDPI and ACS Style

Obleaga, C.V.; Vere, C.C.; Valcea, I.D.; Ciorbagiu, M.C.; Moraru, E.; Mirea, C.S. Helicobacter pylori: Types of Diseases, Diagnosis, Treatment and Causes of Therapeutic Failure. J. Mind Med. Sci. 2016, 3, 150-161. https://doi.org/10.22543/2392-7674.1048

AMA Style

Obleaga CV, Vere CC, Valcea ID, Ciorbagiu MC, Moraru E, Mirea CS. Helicobacter pylori: Types of Diseases, Diagnosis, Treatment and Causes of Therapeutic Failure. Journal of Mind and Medical Sciences. 2016; 3(2):150-161. https://doi.org/10.22543/2392-7674.1048

Chicago/Turabian Style

Obleaga, Cosmin Vasile, Cristin Constantin Vere, Ionica Daniel Valcea, Mihai Calin Ciorbagiu, Emil Moraru, and Cecil Sorin Mirea. 2016. "Helicobacter pylori: Types of Diseases, Diagnosis, Treatment and Causes of Therapeutic Failure" Journal of Mind and Medical Sciences 3, no. 2: 150-161. https://doi.org/10.22543/2392-7674.1048

APA Style

Obleaga, C. V., Vere, C. C., Valcea, I. D., Ciorbagiu, M. C., Moraru, E., & Mirea, C. S. (2016). Helicobacter pylori: Types of Diseases, Diagnosis, Treatment and Causes of Therapeutic Failure. Journal of Mind and Medical Sciences, 3(2), 150-161. https://doi.org/10.22543/2392-7674.1048

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