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Abstract

Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes †

by
Concepción C. González
*,
Jorge Juan Cabrera Trujillo
,
Emy André-Joyaux
,
Antonio J. Herrera
and
Nieves R. Paz
Instituto de Productos Naturales y Agrobiologia CSIC, 38206 San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
*
Author to whom correspondence should be addressed.
†
Presented at the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain, 8 September 2017.
Proceedings 2017, 1(6), 201; https://doi.org/10.3390/proceedings1060201
Published: 6 December 2017
(This article belongs to the Proceedings of Proceedings of the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain)
Versions Notes
Libraries of compounds containing heteroaromatic rings and other nitrogen heterocycles were prepared from sugars and other readily available substrates using sequential scission-addition processes, which save time and materials with respect to conventional processes. Some of these compounds displayed remarkable antimicrobial activity.

Author Contributions

C.C.G. supervised the preparation of new antrimicrobial nitrogen heterocycles carried out by J.J.C.T. and E.A.-J. using alcoxyl radical process; C.C.G. and A.J.H. supervised the chemistry carried out by C.C.G. and N.R.P. using new C-H activation processes.

Acknowledgments

This work was supported by the Research Program SAF-2013-48399-R, Plan Estatal de I+D, Ministerio de Economía y Competitividad, Spain, and European Social Funds (FSE). JJCT Thanks CSIC for a formation Contrat (Garantía Juvenil Programm). EAJ Thanks French Ministry of Higher Education for providing a grant internship.

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Santana, A.G.; Paz, N.R.; Francisco, C.G.; Suárez, E.; González, C.C. Synthesis of Branched Iminosugars through a hypervalent Iodine(III)-Mediated Radical-Polar Crossover Reaction. J. Org. Chem. 2013, 78, 7527–7543. [Google Scholar] [CrossRef] [PubMed]
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MDPI and ACS Style

González, C.C.; Trujillo, J.J.C.; André-Joyaux, E.; Herrera, A.J.; Paz, N.R. Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes. Proceedings 2017, 1, 201. https://doi.org/10.3390/proceedings1060201

AMA Style

González CC, Trujillo JJC, André-Joyaux E, Herrera AJ, Paz NR. Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes. Proceedings. 2017; 1(6):201. https://doi.org/10.3390/proceedings1060201

Chicago/Turabian Style

González, Concepción C., Jorge Juan Cabrera Trujillo, Emy André-Joyaux, Antonio J. Herrera, and Nieves R. Paz. 2017. "Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes" Proceedings 1, no. 6: 201. https://doi.org/10.3390/proceedings1060201

APA Style

González, C. C., Trujillo, J. J. C., André-Joyaux, E., Herrera, A. J., & Paz, N. R. (2017). Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes. Proceedings, 1(6), 201. https://doi.org/10.3390/proceedings1060201

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