Challenges of Antibiotic Resistance: Biofilms and Anti-Biofilm Agents

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiofilm Strategies".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 108

Special Issue Editors


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Guest Editor
Instituto Tecnológico del Valle del Yaqui, Bácum, Sonora, México
Interests: food safety; essential oils; agroindustrial byproducts; antibacterial and antibiofilm agents; quorum sensing
Special Issues, Collections and Topics in MDPI journals

E-Mail
Guest Editor
Instituto Tecnológico del Valle del Yaqui, Bácum, Sonora, México
Interests: food safety; essential oils; bioactive compounds; terpenes; antibacterial and antibiofilm agents
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antibiotic resistance is a global health crisis, as the rise in antibiotic-resistant bacteria has significantly increased the number of deaths each year because infections are becoming increasingly difficult to manage. This resistance is attributed to the overuse and misuse of antibiotics and microorganisms’ ability to form biofilms, which is a significant problem in several sectors, such as healthcare settings, the food industry, and environmental systems. Biofilms are complex communities of microorganisms embedded in a self-produced matrix of extracellular polymeric substances composed of carbohydrates, proteins, lipids, and extracellular DNA. This complex structure protects microorganisms from the action of antibiotics, as well as other environmental stresses. This resilience makes biofilms a critical factor in the growing challenge of antimicrobial resistance. In this sense, there is a need to find new antibiofilm agents that inhibit biofilm development and contribute to reducing bacterial antibiotic resistance.

This Special Issue invites researchers to publish studies regarding new antibiofilm agents (phytochemicals, synthetic drugs, nanoparticles, etc.) and their impacts on biofilms, virulence factors, and antibiotic resistance mechanisms.

Dr. María Melissa Gutiérrez-Pacheco
Dr. Luis Alberto Ortega-Ramirez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibiotic resistance
  • biofilms
  • quorum sensing
  • virulence factors
  • resistance mechanisms
  • antibiofilm agents
  • natural compounds
  • synthetic drugs

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Published Papers

This special issue is now open for submission.
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