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From Small to Large Biomolecule Crystallization Process

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Physics General".

Deadline for manuscript submissions: closed (30 August 2023) | Viewed by 263

Special Issue Editors


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Guest Editor
Department of Chemical Engineering, Imperial College London, London SW7 2BX, UK
Interests: small molecule crystallization; peptide crystallization; protein crystallization; batch and continuous crystallization; peptide conformation; gelation during crystallization; solubility measurement and prediction

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Guest Editor
Department of Chemical Engineering, Loughborough University, Leicestershire LE11 3TT, UK
Interests: biopharmaceuticals crystallization; downstream manufacturing; crystallisation of small organic molecules; interface phenomena; nanotechnologies; stable and unstable phase diagrams
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School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin 300072, China
Interests: particle processes and industrial crystallization; crystal morphology analysis and design; inclusion complexes crystallization

Special Issue Information

Dear Colleagues,

The chain length of biomolecules has a huge effect on their crystallization behavior, even though they have similar groups. The definition of peptides and proteins is only based on their chain length, which raises the following questions: what is the difference between small and large biomolecule crystallization? How does the molecular size affect the solubility, liquid–liquid phase separation, gelation, flexible conformation, and bio-separation?

This Special Issue is dedicated to the topic of biomolecular crystallization, which contains research on amino acids, peptides, proteins, and biopolymers. As a leading expert in this field, we believe that your insights and research would greatly benefit the readers of Applied Sciences. This Special Issue aims to bring together the latest advancements and challenges in understanding the macromolecular crystallization process to provide a platform for exchanging ideas and experiences among scientists in this field. 

Your contribution would help to further the understanding of this important subject and provide valuable information to researchers in the field. We would be honored if you would consider submitting a research paper, review article, or perspective article that reflects your expertise and recent findings. In case you are unable to contribute, we would be grateful if you could forward this invitation to colleagues of yours who may be interested in submitting a paper. We look forward to receiving your contribution and its publication in Applied Sciences.

Dr. Mingxia Guo
Dr. Huaiyu Yang
Dr. Ling Zhou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • amino acid
  • peptide
  • protein crystallization
  • bio-separation
  • solubility
  • gelation
  • liquid-liquid phase separation

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Published Papers

There is no accepted submissions to this special issue at this moment.
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