Application of Bioengineering to Orthopedics

Dear Colleagues,

Orthopaedic surgery is a multi-disciplinary surgical specialism focused on repairing and reconstructing damaged tissues to solve clinical problems. Advancements in biomechanics, biomaterial research, and our understanding of the biological principles of musculoskeletal regeneration and repair are of paramount importance in the discovery and invention of novel diagnostic tools and treatments options that will eventually converge, improving patient outcomes.

Biomechanics represents the major function of the musculoskeletal system. It is also the study of the mechanical behaviour of bones, joints, and tissues under various loads and conditions. By studying the forces and movements that bones and joints experience, researchers can design prosthetics and orthopaedic implants that mimic natural movement, improve stability, and reduce wear over time. This understanding also aids in diagnosing musculoskeletal disorders and developing effective treatment plans. Biomaterial research is vital in developing new scaffolds that can replace or support damaged tissues. In orthopaedics, this involves creating durable, biocompatible materials to support tissue regeneration by living cells, which ultimately supports prosthetic joints, bone grafts, and fixation devices. Biomaterials need to be robust, resistant to wear and corrosion, and capable of integrating into the body without causing adverse reactions. Advances in polymers, ceramics, and metals have revolutionised implant design, extended lifespans, and improved the function of orthopaedic devices.

Biology underpins all aspects of orthopaedics by providing insights into the body's natural healing processes and the behaviour of cells and tissues. A deeper understanding of cellular responses to injury, inflammation, and mechanical stress can provide guiding principles for designs that not only restore functions but also promote tissue regeneration. By incorporating biological principles, bioengineers can develop devices that enhance tissue healing, encourage tissue integration, and reduce complications such as infection or rejection.

In this Special Issue, we will cover recent advances in these key areas of bioengineering for orthopaedic applications.

Dr. Simon Kwoon-ho Chow
Dr. Stuart Goodman
Guest Editors

Manuscript Submission Information

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• orthopaedics
• biomechanics
• biomaterials
• tissue engineering
• regenerative medicine