Chemoprevention to Dwindle Tumor Development
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 26
Special Issue Editor
Interests: oncology proteomics; complementary medicine; oncology; ureteroscopy; punicalagin; proteins
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer causes serious mortality every year. Researchers have devoted much effort and money to curing cancer. However, we have not achieved satisfactory results. There may be a better way to prevent cancer’s appearance rather than to cure it. Thus, cancer chemoprevention may emerge as one of the major strategies for lowering cancer morbidity. Cancer chemoprevention is a pharmacological intervention strategy with naturally present and/or synthetic compounds that may prevent or inhibit carcinogenesis and even suppress the progression of invasive cancer. Indeed, cancer chemoprevention prevents neoplasia progression by stalling neoplastic establishment and switching the formation of transformed cells before the appearance of malignant lesions.
The cornerstone of chemoprevention is uncovering the mechanism of carcinogenesis at the molecular, cellular and animal levels. Carcinogenesis is a multi-stage and multi-pathway process encompassing a series of epigenetic and genetic mutations usually compiled during several years or even decades that shift from normal to increasing grades of dysplasia, ultimately contributing to the emergence of an invasive and metastatic lesion. Thus, the most profound chemoprevention approach is to perform an intervention at an early stage of carcinogenesis using natural or synthetic agents in order to stunt, stop or even reverse the carcinogenesis.
We invite research manuscripts and reviews on the prevention of tumor development at the molecular, cellular or animal levels and clinical studies using natural or synthetic agents.
Prof. Dr. Ting-Feng Wu
Guest Editor
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Keywords
- tumor
- carcinogenesis
- dysplasia
- neoplasm
- chemoprevention
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