Molecular and Pharmacological Basis of Breast Cancer Resistance to Therapies

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 357

Special Issue Editors


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Guest Editor
Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy
Interests: liquid biopsy; pharmacogenetics; ctDNA; treatment resistance; clinical pharmacology; personalized medicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Experimental and Clinical Pharmacology Unit, IRCCS CRO Aviano National Cancer Institute, via Franco Gallini, 2 33081 Aviano, PN, Italy
Interests: personalized medicine, pharmacogenetics, therapeutic drug monitoring, pharmacoeconomics, healthcare economics, clinical pharmacology

Special Issue Information

Dear Colleagues,

We would like to draw your attention to the importance of conducting comprehensive evaluations related to breast cancer within the context of our upcoming special issue, titled "Molecular and Pharmacological Basis of Breast Cancer Resistance to Therapies." In light of the profound impact of breast cancer on individuals, families, and society at large, we emphasize and prioritize the rigorous assessment of this disease.

Breast cancer remains a critical global health issue, affecting millions of individuals worldwide. In our quest for innovative solutions and improved treatment strategies, the evaluation of breast cancer takes on a central role. Importantly, the tumour genetic landscape influences treatment response in cancer patients. Multiple molecular mechanisms of resistance to therapies in breast cancer have been discussed, highlighting the degree of tumours’ heterogeneity.

This evaluation primarily focuses on:

  • Resistance Mechanisms: Investigating the intricate molecular pathways and genetic factors that drive resistance to anticancer therapies in breast cancer is crucial for developing more effective treatment approaches.
  • Personalized Treatment Approaches: Evaluating the potential for tailoring breast cancer treatments based on individual patient characteristics and safety profiles is a key focus in our efforts to improve patient outcomes.
  • We believe that by emphasizing these critical aspects of breast cancer evaluation, particularly the mechanisms underlying resistance to anticancer treatment, we can make significant strides in our collective mission to combat this disease.

I/We look forward to receiving your contributions.

Dr. Stefania Crucitta
Dr. Rossana Roncato
Guest Editors

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Keywords

  • breast cancer
  • resistance mechanisms
  • personalized treatment approaches

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