Hepatocellular Carcinoma: From Genomic and Epigenomic Regulation to Drug Discovery
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 445
Special Issue Editors
Interests: hepatocellular carcinoma; drug discovery; genetic alteration; prostate cancer
Interests: drug screening and discovery; drug application of natural compounds; hepatocellular carcinoma; immunotherapy from natural compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hepatocellular carcinoma (HCC) is one of the most common types of liver cancer and is responsible for a significant proportion of cancer-related deaths worldwide. Understanding the molecular mechanisms underlying HCC development and progression is crucial for the development of new diagnostic and therapeutic strategies. This Special Issue aims to gather original research articles, reviews, and perspectives related to the genomic and epigenomic regulation of HCC, including the identification of the key molecular mechanisms involved in the pathogenesis and progression of HCC. Furthermore, the Special Issue will also highlight the current state of the art in drug discovery for HCC, including novel targeted therapies and immunotherapies.
Potential topics of interest include, but are not limited to:
- Genomic and epigenomic profiling of HCC;
- Molecular mechanisms involved in HCC pathogenesis and progression;
- Biomarkers for early detection and prognosis of HCC;
- Targeted therapies for HCC;
- Immunotherapies for HCC;
- Drug-resistance mechanisms in HCC;
- Preclinical and clinical studies of HCC therapeutics
The goal of this Special Issue is to provide a comprehensive overview of the latest advances in the field of HCC research, which will be of interest to researchers, clinicians, and drug developers working in this area.
Dr. Feiyu Chen
Dr. Zhangfeng Zhong
Guest Editors
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Keywords
- genomic and epigenomic modulation
- hepatic tumorigenesis signaling pathway
- in vitro models for studying HCC
- in vivo models for studying HCC, MRI, CT, and potential therapeutic strategies
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