Immunonutrition: Biomedical Basis for Disease Management 2.0
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 266
Special Issue Editor
Interests: immunonutrition; macrophages; trained immunity; gut-liver axis; microbiota
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Knowledge about the impact of immunonutritional agonists on citizens’ health can offer a way to reduce the risk of suffering chronic diseases and even offer a therapeutic potential on these. Innate and adaptive immune effectors operate sequentially and in distinct ways during normal development to prevent alterations in tissue metabolic homeostasis as well as to establish steady-state commensalism. Those are key to correct the distinctive stamp in alterations to the homeostasis of nutrients, leading to immunometabolic-based diseases with a strong impact on future morbidity rates and a reduction in the life expectancy of the population (i.e., non-alcoholic fatty liver disease, metabolic syndrome, cancer). There is evidence of the relevance of perinatal nutrition to developmental programming of innate immune effectors, worsening or improving their contribution to the risk of disease development. Viewed in the context of innate immune biology, immunonutrition as coadjutant strategy to pharmacological approaches can represent a path forward to help to selectively develop and maintain durable and long-lasting immune response(s). However, there remain key unanswered questions about immunonutritional factors that overall require a concerted effort to overcome the usually fragmented and compartmentalized approach to address their impact. Identification and development of immunonutritional agonists, as well as definition of their biomedical action based on life sciences, can greatly accelerate our progress toward precision medicine in health promotion.
Dr. Jose Laparra Llopis
Guest Editor
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Keywords
- nutrients
- innate and adaptive lymphocytes
- myeloid cells
- cancer
- lipid homeostasis
- microbiota
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