Novel Approaches for Diagnosis and Treatment of Pancreatic Cancer
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 141
Special Issue Editor
Interests: colorectal and pancreatic cancer; diagnostic biomarkers; exosomes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer can appear anywhere in the body, due to the accumulation of mutations and other genomic aberrations that lead to uncontrolled cell proliferation, inhibition of apoptosis, and an increased cell migration. Tumour cells are able to activate thorough mechanisms to generate a tumour from early stages and generate metastases through the induction of epithelial-to-mesenchymal transition, angiogenesis, and an immunosuppressive microenvironment. Other crucial events in tumourigenesis are the emergence of the undifferentiated phenotype and the generation and maintenance of cancer stem cells. In carcinogenesis, the co-activation of several genes and pathways is common, and the study of these factors and signalling pathways has greatly helped us to identify new targets for drug design. These drugs could be chemically synthesized or isolated from natural substances. These novel molecules could represent a massive step forward in reaching personalized medicine in the present clinical management of pancreatic cancer.
In this Special Issue entitled "Novel Approaches for Diagnosis and Treatment of Pancreatic Cancer", we encourage authors to submit high-quality research articles dealing with new diagnostic biomarkers and promising biomolecules that improve treatment response and survival and provide an outstanding rationale of their anti-tumour activity to the scientific and clinical community. This activity could be observed in both in vitro and/or in vivo models. In addition, we are open to receiving updated reviews about novel molecules with high potential to be used as diagnostic biomarkers or in the design of new treatment approaches.
Dr. Javier Martinez-Useros
Guest Editor
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Keywords
- pancreatic cancer
- small molecules
- monoclonal antibodies
- antibody-drug conjugated
- personalized therapy
- immunotherapy
- natural compounds
- exosomes
- nanoparticles
- biomarkers
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