Advanced Research in Antiviral Innate Immunity

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 139

Special Issue Editor


E-Mail Website
Guest Editor
Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL, USA
Interests: antiviral innate immunity; RLR signaling; cGAS-STING signaling; PTM; virus–host interaction; viral evasion

Special Issue Information

Dear Colleagues,

This Special Issue aims to provide a comprehensive platform for the latest discoveries and advancements in antiviral innate immune signaling. It will focus on the intricate regulatory mechanisms that sustain the host's innate immune responses to viral infections, emphasizing key pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs), RIG-I-like receptors (RLRs), and cGAS, along with their downstream signaling pathways.

Recent research has underscored the crucial roles that these PRRs and their downstream signaling pathways play in detecting viral pathogens and orchestrating an effective immune response. Understanding these regulatory mechanisms is vital for developing novel therapeutic strategies with which to enhance antiviral immunity and control viral diseases. This Special Issue seeks contributions that explore novel insights and regulatory mechanisms, including post-translational modifications (PTMs), the phase separation of PRRs or their downstream signaling molecules, and the interplay between different signaling pathways in antiviral immunity. Reviews and original articles employing advanced techniques, such as molecular biology, genetics, and bioinformatics, to unravel these complex processes are particularly welcome.

By gathering cutting-edge research, this Special Issue will serve as a valuable resource for scientists and clinicians aiming to deepen their understanding of antiviral innate immunity and develop innovative interventions against viral infections.

Dr. Junji Zhu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antiviral immunity
  • innate immune signaling
  • toll-like receptors (TLRs)
  • RIG-I-like receptors (RLRs)
  • cGAS-STING pathway
  • type I interferon
  • viral infection
  • post-translational modification (PTM)
  • phase separation
  • host–pathogen interactions
  • therapeutic strategies

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Published Papers

This special issue is now open for submission.
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