Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

Dear Colleagues,

As the area of brain injury research continues to evolve rapidly, significant strides have been made in recent years toward understanding the complex pathophysiology of acquired brain injuries. Every year, upwards of 85 million people suffer from brain injuries, primarily caused by trauma or stroke. Nevertheless, the central nervous system remains uniquely challenging to treat due to its complex structure and limited regenerative capacity. Thus far, therapeutic approaches have concentrated on minimizing injury sequelae and maximizing the function of remaining brain tissue, but they have not fully addressed the regeneration and replacement of damaged tissue.

Building upon the foundation of our previous issue, this second-edition Special Issue will focus on recent advancements and emerging strategies, including nanotechnology, tissue engineering, and other innovative approaches, to repair, regenerate, and restore central nervous system functionality. We aim to showcase cutting-edge research from preclinical and clinical studies, as well as comprehensive reviews that contextualize recent breakthroughs.

We invite submissions that investigate novel regenerative and restoration techniques, with an emphasis on bridging neuronal gaps, reconnecting severed neural pathways, and promoting neural tissue regeneration. Additionally, we encourage studies that uncover new insights into the neuropathological molecular mechanisms underlying brain injury, providing a foundation for future targeted therapies.

Through this Special Issue, we hope to provide insight into the research efforts that move us closer to fully functional regenerative solutions for brain injuries. We look forward to your contributions as we collectively advance the science of brain injury treatment and neuroregeneration.

Dr. Kristina Pilipović
Dr. Petra Dolenec
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• acquired brain injury
• nanomedicine
• nanotechnology
• neuroregenerative therapy
• neurorepair
• new and emerging treatments
• pharmacotherapy
• stroke
• tissue engineering
• traumatic brain injury

• Brain Injury: New Insights into Mechanisms and Future Promising Treatments in Biomedicines (11 articles)