Biomarkers in Motor Neuron Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 372
Special Issue Editor
2. Neurology Unit, Department of Neuroscience, Azienda Ospedaliero Universitaria di Modena, 41126 Modena, Italy
Interests: amyotrophic lateral sclerosis; neurological diseases; neuroepidemiology; neurodegeneration; neuroinflammation; neurogenetics; microbiota
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases are characterized by extreme genetic, pathology, and phenotype heterogeneity, which is one of the major causes of clinical trial failure and substantial absence of effective treatments. Although different potential candidate biomarkers of disease have been the object of recent research, their use in clinics and trials is still limited.
If a diagnostic biomarker were to decrease diagnostic delay, allowing for earlier treatments, prognostic biomarkers would help in patients’ counselling and stratification in clinical trials. Pharmacodynamic and predictive biomarkers would be very useful as well, in translational and clinical research.
This Special Issue aims to collect high-quality papers on emerging research on biomarkers in motor neuron diseases, with special consideration of neurodegeneration and neuroinflammation processes and biological and clinical heterogeneity. We believe this field will take advantage of multidisciplinary approaches; hence, contributions including basic, translational, and clinical studies are strongly encouraged.
Prof. Dr. Jessica Mandrioli
Guest Editor
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Keywords
- neurodegenerative diseases
- motor neuron diseases
- dementia
- neurodegeneration
- epidemiology
- pathomechanisms
- neuroinflammation
- neuroimmunology
- gut–brain axis
- disease heterogeneity
- prognosis
- biomarkers
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