Exploration of the Brain Structural Changes in Patients with Mental Illness
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropsychiatry".
Deadline for manuscript submissions: 15 June 2025 | Viewed by 184
Special Issue Editor
Interests: neuropsychiatric disorders; clinical and translational neuroscience and psychology; genomics and epigenomics; pharmaceutical sciences; social determinants of health and policy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The human brain is a highly complex organ, with interconnected neurons, neuronal circuitry, and brain regions forming its structure and enabling its function. Structural abnormalities in the brain have been observed in various neurological disorders such as Alzheimer’s disease, Parkinson’s disease, and Huntington's disease, leading to significant loss of neuronal structure and function. However, recent advancements in neuroimaging techniques, artificial intelligence, and human connectome projects have opened up new horizons in our understanding of the brain. These advancements offer hope for a deeper understanding of the structure of the human brain at different levels from neurons and synapses (microscale) to brain regions and pathways (macroscale) and their role in mental illnesses.
This Special Issue aims to gather research that explores the potential links between differences in brain structure and the onset and progression of various mental illnesses. Studies may focus on identifying abnormalities in specific brain regions associated with certain disorders, such as the prefrontal cortex in depression or the amygdala in post-traumatic stress disorder. Additionally, research may delve into how improvements in neuroimaging techniques have contributed to our understanding of these connections, including the relationships between brain structural and functional connectivity and the impact of brain structure on mental disorders.
Dr. Fengyu Zhang
Guest Editor
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Keywords
- psychiatric diseases
- human brain connectome
- biomarkers
- endophenotypes
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