The Role of Opioid Peptides in Psychostimulant Addiction
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Developmental Neuroscience".
Deadline for manuscript submissions: closed (25 February 2020) | Viewed by 801
Special Issue Editor
Interests: neuropeptides; drug and natural reward; pain; addiction; psychostimulants and other addictive drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Opioid peptides are found in the central nervous system (CNS) and peripheral nervous system (PNS) and have long been implicated in the modulation of pain, the regulation of the stress response, feeding, motivated behaviors, etc. Opioid peptides have also been known to regulate the activity of the mesolimbic dopaminergic neurons that are associated with the rewarding and reinforcing actions of addictive drugs, such as psychostimulants, alcohol, and nicotine. Accumulating evidence suggests that opioid peptides are also involved in the rewarding and reinforcing actions of amphetamine and cocaine. A comprehensive review of the role of each opioid peptide in the rewarding and reinforcing actions of amphetamine and cocaine is essential. This research topic focuses on the role of opioid peptides in the rewarding and reinforcing actions of psychostimulants as well as negative affective states, such as anxiety, depression, and anhedonia, which are associated with withdrawal from such reinforcers. This research topic is also expected to establish a link between opioid peptides and the development of psychostimulant addiction and other neuropsychiatric disorders associated with the continued use of these drugs as well as following their withdrawal.
Prof. Dr. Kabirullah Lutfy
Guest Editor
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Keywords
- Reward and/or reinforcement
- Withdrawal and/or reinstatement
- Psychostimulant addiction
- Cocaine
- Amphetamine and/or methamphetamine
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