Novel Insights into the Multidisciplinary Management of Colorectal Cancer
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 25 March 2025 | Viewed by 92
Special Issue Editors
Interests: colon cancer; neuroendocrine tumors; gastric cancer
Interests: colorectal cancer; hepatobiliary cancer; gastric cancer; pancreatic cancer; clinical trials; translational research
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Colorectal cancer (CRC) is the third most common cancer worldwide, accounting for approximately 10% of all cancer cases, and is the second leading cause of cancer-related deaths worldwide. Biomarker-based stratification of metastatic CRC enables the use of precision therapy based on individual tumor mutational profiles. Activating mutations in the RAS/RAF/MAPK pathway downstream of EGFR signaling have, until recently, limited the use of EGFR-targeted therapies for mCRC; however, the development of anti-RAS and anti-RAF therapies, together with improved strategies to limit compensatory signaling pathways, is resulting in improved survival, which in recent clinical trials approaches 30 months. The aim of this Special Issue is to provide novel insights into the multidisciplinary management of CRC, with a special emphasis on novel approaches in the treatment of metastatic disease.
Dr. Fabio Gelsomino
Dr. Francesco Caputo
Guest Editors
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Keywords
- colorectal cancer
- precision medicine
- targeted therapy
- immunotherapy
- liver metastases
- peritoneal metastases
- surgery
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