Medical Metal Surface Functionalization Construction
A special issue of Metals (ISSN 2075-4701). This special issue belongs to the section "Biobased and Biodegradable Metals".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 21
Special Issue Editor
2. Department of Natural Sciences, Mathematics and Statistics, Federal Rural University of Semiarid Region, Mossoro 59625-900, Brazil
Interests: biomaterials; plasma treatment surfaces; cell adhesion; titanium; biocompatiblity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The functionalization of metal surfaces in the medical field plays a crucial role in advancing biomaterial technology, specifically in implants, stents, and prosthetic devices, where surface properties are key to improving patient outcomes. Medical metal surface functionalization aims to tailor surface characteristics like wettability, roughness, porosity, and chemical composition, which are directly correlated with bioactivity, tissue integration, and cellular responses. By engineering surfaces with precisely controlled features, cellular adhesion can be enhanced, bacterial colonization can be reduced, and overall biocompatibility can be significantly improved.
Despite its potential, creating medical metal surfaces with these controlled properties presents several challenges. Achieving stable and reproducible wettability, for instance, is technically demanding due to surface energy variations over time and exposure to biological fluids. Similarly, precise porosity control requires advanced manufacturing techniques, such as additive manufacturing or electrochemical deposition, which often involve complex and costly processes. Chemical composition customization, while advantageous, raises issues with long-term stability, as coatings can degrade or leach harmful ions. Another challenge lies in ensuring that functionalized surfaces maintain their mechanical integrity without compromising the durability of the device.
Thus, this Special Issue aims to present the most recent experimental developments, as well as methods for modeling and simulating processes, aiming to improve a medical metal surface. In this context, advances in nanotechnology, surface modification methods, and metal 3D printers are paving the way for safer, more effective medical devices that meet the complex requirements of clinical applications.
Prof. Dr. Clodomiro Alves Junior
Guest Editor
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Keywords
- biomaterial
- surface properties
- cellular adhesion
- bacterial colonization
- biocompatibility
- wettability control
- topography
- advanced manufacturing techniques
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