Anti-Adipogenic and Anti-Inflammatory Properties of Natural Products
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 15 March 2025 | Viewed by 70
Special Issue Editor
Special Issue Information
Dear Colleagues,
Obesity and chronic inflammation are major health issues in the modern world, significantly contributing to the global burden of non-communicable diseases such as type 2 diabetes, cardiovascular diseases, and metabolic syndrome. The role of natural products in preventing or reducing adipogenesis and inflammation has gained increasing attention due to their potential therapeutic benefits and reduced amount of side effects compared to synthetic drugs.
Citrus fruits, herbs, and various plant-based compounds, such as flavonoids and polyphenols, have shown promising results in regulating lipid metabolism, fat accumulation, and inflammatory pathways. However, the underlying mechanisms by which these natural products exert their anti-adipogenic and anti-inflammatory effects are not fully understood. In particular, the modulation of gene expression, enzyme activity, and signaling pathways such as AMP-activated protein kinase (AMPK) or nuclear factor kappa B (NF-κB) may be key factors.
This Special Issue aims to highlight recent advances in identifying and understanding the mechanisms of action of natural products with anti-adipogenic and anti-inflammatory properties. Contributions will explore the potential of natural compounds, either isolated or in combination, to act as preventive or therapeutic agents against obesity, inflammation, and associated diseases. Studies addressing the regulation of key metabolic genes, lipid biosynthesis, adipocyte differentiation, and inflammatory markers are encouraged. Moreover, in silico studies, in vitro, and in vivo models that investigate the efficacy of these natural agents in modulating inflammation and adipogenesis will be covered.
Prof. Dr. Youngjae Lee
Guest Editor
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Keywords
- adipogenesis
- inflammation
- phytochemicals
- flavonoids
- polyphenol metabolism
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