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Surface Modifications of Biomaterials for Biomedical Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 August 2025

Special Issue Editor


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Guest Editor
School of Medicine and Health Engineering, Changzhou University, Changzhou, China
Interests: biomedical materials; drug delivery system; nanomaterials; medical devices; tissue engineering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

 

Biomaterials with excellent performance and functions have wide applications in tissue engineering and implantable medical devices, playing an increasingly prominent role in the diagnosis and treatment of human diseases and promoting human health. After being implanted into the human body, biomaterials first interact with physiological environments such as body fluids, cells, and tissues through their surfaces. The surface and interface of the implanted biomaterial are the first places to directly communicate with the physiological microenvironment of human body. Therefore, the physical and chemical structure and 

characteristics of the biomaterial surface can directly affect the physiological reactions between the material and the host. This further affects the biological properties of the biomaterial and the physiological responses of the host, ultimately determining the service performance and clinical outcome of the biomaterials. The surface modification of biomaterials represents one of the main ways to enhance the biocompatibility of existing medical materials and provides an important academic foundation for the development of next-generation tissue regeneration biomaterials. Although biomaterial surface modification technologies have advanced in recent decades, the biocompatibility and biofunctionality of current artificial biomaterials, such as metals, ceramics, and polymers, need to be further improved and optimized to adapt to different diseases and better exert their performance and function. The surface modification of biomaterials belongs to an interdisciplinary field, involving surface structure design and preparation, surface characterization, chemical reactions for surface functionalization, biological responses caused by surface contact with living organisms, etc.

The goal of this Special Issue is to cover current advances in “Surface Modifications of Biomaterials for Biomedical Applications”, including the design and fabrication of advanced biomaterials, state-of-the-art advances in the surface modification of biomaterials, the construction of multifunctional collaborative surfaces and interfaces, the mechanisms of interaction between biomaterials and hosts, precise surface fabrication technology, surface characterization technologies for biomaterials, the clinical application of surface modification technologies, etc.

Keywords

  • biomaterial
  • scaffold
  • surface modification
  • surface characterization
  • biofabrication
  • surface and interface reactions
  • tissue engineering
  • biocompatibility
  • surface modification for 3D printing biomaterials
  • medical devices
  • surface simulation

 

Professor Changjiang Pan

Prof. Dr. Changjiang Pan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterial
  • surface modification
  • surface characterization
  • surface and interface reactions
  • tissue engineering
  • biocompatibility
  • surface modification for 3D printing biomaterials
  • surface simulation

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