Natural and Synthetic Polyenes
Special Issue Editors
Interests: antioxidant; enzyme; glutathione; prooxidant; activity; metabolic disease
Special Issues, Collections and Topics in MDPI journals
Interests: mitochondria; oxidative stress; biomacromolecules; respiratory chain; antioxidants
Special Issue Information
Substances with a linear polyunsaturated chain, characterized by at least three unsaturated bonds, belong to the broad group of polyenes. These compounds exhibit remarkable biological properties due to their propensity for aggregation, conjugation, and oxidation. The diversity of polyenes enables them to fulfill various physiological functions and influence regulatory processes, such as those involving polyunsaturated fatty acids and their oxidation products. These substances play crucial roles in membrane functions, immune responses, vision, and the promotion of tissue growth, proliferation, and differentiation. The presence of double bonds in their structure makes them susceptible to both enzymatic and non-enzymatic oxidation, a process fundamental to many pathophysiological events. Interestingly, in some cases, this oxidation mediates antioxidant activity. Synthetic derivatives of polyenes also play a significant role as therapeutic agents, offering considerable benefits in medical applications.
Dr. Janka Vašková
Dr. Marek Stupák
Dr. Jozef Židzik
Guest Editors
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Keywords
- polyunsaturated
- fatty acids
- carotenoids
- retinoids
- pigments
- oxidation
- treatment
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