Biomarkers for Early Detection of Viral Infections: Current Status and Challenges
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 281
Special Issue Editors
Interests: polyomaviruses; herpesviruses; HBV; latent viral infections; viral infection in immunosuppressed patients; oncogenic viruses; autoimmunity and viruses
Interests: EBV; herpesviruses; oncogenic viruses; genetic variability; autoimmunity
Interests: hepatitis viruses; HBV; viral genetic variability; antiviral resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The harm of viral infections to public health is obvious. They can spread rapidly, causing large-scale epidemics, and greatly impact human health and economic development. Due to their infectivity and variability, detecting viral infections has become a challenge in medical research. Viral biomarkers are specific molecules that indicate the presence of a virus in host–cell or biological/clinical samples. These biomarkers can be nucleic acid (DNA or RNA)-based, proteins/antigens, specific antibodies, or host responses (changes in gene expression, cytokine release, etc.). All these biomarkers can be identified, detected, and measured using different techniques including emerging technologies such as NGS, microarray, and proteomics. This is crucial for the diagnosis and monitoring of viral infections, assessment of treatment strategy, and vaccine development.
Although some progress has been made in applying biomarkers and detection methods, there are still some challenges. Biomarkers need to be sensitive and specific to enable early detection of viral infection, need to be validated and standardized, can be used as a point-of-care test, and can be integrated into clinical protocols to improve patient outcomes.
What are the future directions for viral biomarkers? It is necessary to integrate the newest technologies, an omics approach, machine learning, and AI with the collaborative efforts of scientists from different fields and regions.
This Special Issue welcomes original research papers, review articles, communications, etc. Submissions should cover the latest research findings, progress in the study of biomarkers for early detection of viral infections, and the role of biomarkers in the prognosis assessment and treatment strategy formulation of viral infections. We hope this Special Issue will provide a platform for researchers in the field of viral infections to exchange ideas and promote the development of Biomarkers for Early Detection research and clinical applications in viral infections.
Dr. Danijela Miljanovic
Dr. Ana Banko
Prof. Dr. Ivana Lazarevic
Guest Editors
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Keywords
- viral detection
- biomarkers
- nucleic acid (DNA, RNA)
- viral proteins
- antibodies
- host response
- NGS
- omics approach
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