Candida albicans Virulence and Therapeutic Strategies
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Fungal Pathogens".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 5
Special Issue Editors
Interests: Candida species; alternative therapies; natural compounds; biofilms; resistance patterns; host-interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Candida albicans is an opportunistic pathogenic yeast and is recognized as one of the most common opportunistic fungal pathogens in humans, responsible for 60% of mucosal infections and 40% of candidemia cases. Its capacity to induce a range of infections from localized to systemic and life-threatening poses significant challenges to modern medicine. Current research is focused on uncovering the complex mechanisms behind its virulence, which include the ability to form biofilms, evade the host immune system, and develop drug resistance. This Special Issue seeks to compile cutting-edge research addressing the mechanisms underlying its virulence, resistance, and host interactions, as well as innovative therapeutic strategies to combat these infections.
Accepted topics include, but are not limited to, the following:
- Virulence factors: insights into the genetic, molecular, and biochemical mechanisms that contribute to the pathogenicity of C. albicans.
- Biofilm formation: exploration of the processes driving biofilm development and their role in infection persistence and drug resistance.
- Antimicrobial resistance mechanisms: studies focusing on the development of resistance to antifungal therapies in C. albicans, with an emphasis on metabolic adaptations, genetic pathways, and their role in treatment failure.
- Host–pathogen interactions: research on the interaction between C. albicans and the host immune system, highlighting evasion strategies and immune responses.
- Novel therapeutic strategies: innovative approaches for treating C. albicans infections, including new antifungal agents, biofilm-disrupting compounds, and combination therapies.
- Molecular and biochemical pathways: examination of the pathways driving the virulence and resistance of C. albicans in different environments.
Original research papers showcasing recent discoveries are encouraged, alongside comprehensive review articles and comparative studies.
We look forward to your contributions.
Dr. Maria Elisa Rodrigues
Dr. Liliana Fernandes
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Candida albicans
- virulence factors
- biofilm
- antimicrobial resistance
- therapeutic strategies
- host interactions
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