Advances in Oral Delivery of Lipid Nanoparticles for Treating Inflammatory Diseases

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 20 January 2025 | Viewed by 206

Special Issue Editors


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Guest Editor
1. Digestive Disease Research Group, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA
2. State Key Laboratory of Silkworm Genome Biology, Key Laboratory for Sericulture Functional Genomics & Biotechnology of Agricultural Ministry, Southwest University, Beibei, Chongqing 400716, China
Interests: inflammatory bowel diseases; nanomedicines; drug delivery
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Guest Editor
Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21250, USA
Interests: nanoparticles; nanomedicine; targeted drug delivery

Special Issue Information

Dear Colleagues,

Oral delivery of lipid nanoparticles (LNPs) offers a promising approach for treating inflammatory diseases by enhancing the bioavailability and targeted delivery of therapeutic agents. LNPs can encapsulate anti-inflammatory drugs, protecting them from degradation in the gastrointestinal tract and facilitating their absorption through the intestinal lining. This method ensures controlled and sustained medication release, reducing the frequency of dosing and potentially minimizing side effects. Despite its potential, the design and preparation of orally deliverable LNPs face challenges, such as combating the complexity of inflammatory responses and requiring precise control over the size, surface charge, and composition of the particles. The development of new oral drug delivery systems may contribute to overcoming these difficulties.

This Special Issue aims to highlight the current progress in the use of orally delivered lipid nanoparticles as nanocarriers and nanotherapeutics in inflammatory diseases.

Dr. Dingpei Long
Dr. Junsik Sung
Guest Editors

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Keywords

  • oral administration
  • inflammatory diseases
  • targeted drug delivery
  • lipid nanoparticles
  • engineered lipid nanoparticles

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