Preparation and Development of Amorphous Solid Dispersions
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 66
Special Issue Editors
Interests: drug delivery systems; biomaterials; functional foods; pharmaceutical products; wound care
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Amorphous solid dispersions (ASDs) have emerged as a key strategy with which to enhance the bioavailability of poorly water-soluble drugs. By converting crystalline drugs into amorphous forms and stabilising them in a polymer matrix, ASDs can significantly improve their solubility, dissolution rate, and absorption. However, challenges related to their stability, manufacturing, and scalability remain active research areas.
This Special Issue seeks to explore recent advances in the preparation, characterisation, and development of ASDs. We invite original research articles and reviews on novel preparation techniques, stabilisation mechanisms, in vitro and in vivo performance, and industrial applications. Contributions addressing challenges in process optimisation, scale-up, and regulatory considerations are encouraged.
We look forward to your submissions, which will contribute to advancing the field of amorphous solid dispersions and enhancing the therapeutic effectiveness of drugs.
Prof. Dr. Judyta Cielecka-Piontek
Dr. Szymon Sip
Guest Editors
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Keywords
- amorphous solid dispersions
- drug solubility enhancement
- bioavailability improvement
- polymer matrix stabilization
- pharmaceutical formulation
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