Whole-Cell Biosensors: Recent Advances
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".
Deadline for manuscript submissions: closed (15 October 2021) | Viewed by 1180
Special Issue Editor
Interests: drug delivery vehicles; tissue engineering; clay nanomaterials; colloid chemistry; correlative microscopy; cell surface engineering; nanotoxicology; spectroscopy
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Special Issue Information
Fabrication of whole-cell biosensors is a fascinating direction in bioanalytical chemistry. Arguably, whole-cell biosensors represent the most interesting and intriguing part of the biosensors family. In whole-cell biosensor, we benefit from the analytical response of the cellular machinery orchestrated by the synergy of nucleic acids and enzymes. Essentially, the simplest (yet fully functional) whole-cell biosensors do not even require any physical transduser, relying on direct observations of cellular responses to various analytes manifested in luminescence intesity changes or similar sygnals. More elaborate devices, in general, follow the classical biosensor setup structure, where the biological sensing elements (live cells) are incorporated into a certain elecronic device capable of sensing the (bio)chemical changes within the cells. This opens avenues for effective and selective detection of various analytes. Therefore, whole-cell biosensors hold a great promise in current bioanalytical chemistry, attracting attention of the researchers worldwide.
This Special Issue is focused on recent advances in the field of whole-cells biosensors. Both review and original research articles are invited. In addition to papers reproting the fabrication and applications of whole-cell biosensors, contributions featuring other areas related to whole-cells biosensors, such as genetic modifications of reporter cell or cell immobilisation or cell surface modifications. In addition, manuscripts reporting technological advances towards more effective whole-cell biosensors, such as development of novel analytical platforms, improvement of data acquisition and introduction of novel measurement or data processing techniques will be considered.
Prof. Dr. Rawil F. Fakhrullin
Guest Editor
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Keywords
- Whole-cell biosensors
- Diagnostics
- Reporter cells
- Microfluidic biosensing devices
- Electrochemical biosensors
- Cell surface engineering
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