Animals Venom in Drug Discovery: A Valuable Therapeutic Tool
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Animal Venoms".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 186
Special Issue Editors
Interests: snake venom; senescence; aging; bioactive molecules; calcium channels
2. Department of Biology, Faculty of Sciences 3, Campus Michel Slayman Ras Maska, Lebanese University, Tripoli 1352, Lebanon
Interests: toxins; venoms; pharmacology; scorpion venoms; biological therapy; biomolecular interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Animal venoms are a rich source of valuable pharmaceutical molecules. These complex mixtures of proteins and other bioactive molecules are mainly used for predation and defense. However, venom compounds exhibit many interesting biological activities including anti-oxidant, anti-coagulant, anti-inflammatory, and anti-cancer properties, thus offering unique bioactive molecules with high specificity and potency that make them interesting candidates for drug development. Technological advancements, such as high-throughput screening, genomics, and proteomics, support the discovery and development of new drugs from venoms. The broad sources of venoms (snake, spider, bee, scorpions, etc.) combined with the large panel of biological activities associated with diseases position animal venoms as a major resource for biological research. This being said, a vast majority of venomous animals and their therapeutic potential have not yet been explored.
In this Special Issue, we aim to provide scholars with the latest research on animal venom-based drug discovery, covering everything from the early phases of venom collection to advanced clinical trials, including fractionation, bioactivity, and characterization. To enhance our understanding of these processes, we invite experts in the field of animal venoms to contribute via research papers and reviews dissecting the molecular complexity of animal venoms in drug discovery. All aspects of animal venom-based drug discovery, including cellular, molecular, structural, and -omics studies, are of great interest.
Dr. Mohamad Rima
Prof. Dr. Ziad Fajloun
Guest Editors
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Keywords
- venoms
- toxins
- calcium channels
- proteomics
- transcriptomics
- bioactive molecules
- bioinformatics
- venomous animals
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