Insights into Fish Venoms
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Animal Venoms".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 439
Special Issue Editors
Interests: venomous fish toxins as molecular tools to study the mechanisms underlying inflammatory processes; recapitulating immune-mediated inflammatory diseases in zebrafish embryos
Special Issues, Collections and Topics in MDPI journals
Interests: identification of mechanistic biomarkers of metabolic processes and pathways of venomous fish toxins and drugs, using zebrafish embryos as a preclinical pharmacotoxicology model organism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The production of toxins by fish is an important strategy that guarantees their survival in a highly competitive ecosystem. Venomous fish have glands specialized in the secretion of toxic substances and specialized apparatus for inoculating the venom, such as rostrums, teeth, and canaliculated spines. Venomous fish produce a distinct combination of toxic components, including peptides and proteins with particular noxious characteristics. Venomous fish have been studied to learn more about the pathophysiology of the envenomation in humans and to identify the biochemical nature of their toxins. Recently, investigations of cellular and molecular mechanisms adjacent to fish envenoming have mapped genes and receptors in innate cells that recognize these molecules and, consequently, new pharmacological targets. Furthermore, the identification of new protein families in fish venoms and their characterization as molecules that are responsible for immune defense, signaling, and development have challenged old notions on their role as a toxin. Today, there is great interest from the pharmaceutical industry in exploring molecules derived from venomous fish for drug development.
This Special Issue aims to collate the current scholarly work on fish venoms from active scholars and researchers.
Dr. Carla Lima
Prof. Dr. Mônica Lopes-Ferreira
Guest Editors
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Keywords
- venomous fish
- envenomation pathophysiology
- pharmacological treatment
- polyclonal antiserum new families of proteins
- peptides
- the function of venom molecules in the immune response
- role in conserved functions such as immune responses
- signaling and development
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