Decreased Expression of Plakophilin-2 and αT-Catenin in Arrhythmogenic Right Ventricular Cardiomyopathy: Potential Markers for Diagnosis
, Fa-Po Chung 1,2,*,†, Chung-Lieh Hung 3,4,5, Yenn-Jiang Lin 1,2, Tzu-Ting Kuo 2,6, Jo-Nan Liao 1,2, Yun-Yu Chen 1,7, Chih-Hsin Pan 8, Kai-Ping Shaw 8 and Shih-Ann Chen 1,2Round 1
Reviewer 1 Report
Dear Authors,
I congratulate you for the interesting article. I have some minor suggestions.
Abstract - You should be more specific about the purpose of the study.
Introduction - well written.
The Materials and Methods section should be the second Section.
Results -
- Figure 1 should be moved after the section of the text that mentions it
- For Figure 1c, the results are described in the text; it does not need to be written in the legend of the figure also
- Line 152 and 166 with references 19 and 21 should be moved to the Introduction chapter
- Figure 3- I think it should be split into two or more, for a better understanding
Discussion - Well written
Author Response
Please see the attachment.
Author Response File: 
Author Response.docx
Reviewer 2 Report
This manuscript studies the expression potential biomarkers plakophilin-2 and αT-catenin in cardiac disease. The data presented is clear and easy to understand. I believe the findings are clinically relevant and are supported by proper results. However, discussion can be improved.
Overall, manuscript is good and will attract wide readership.
Author Response
Please see the attachment.
Author Response File: Author Response.docx
