Molbank

150 KiB

Open AccessCorrection

Synthesis of 8-Chloro-11-(4-(3-(p-tolyloxy)propyl)piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

by Ben Capuano, Ian T. Crosby, Sean E. K. Lim, Edward J. Lloyd and Elizabeth Yuriev

Molbank 2006, 2006(2), M475; https://doi.org/10.3390/M475 - 29 Mar 2006

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491 KiB

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5,5’-Biindole

by Ramiro Quintanilla-Licea, Juan F. Colunga-Valladares, Adolfo Caballero-Quintero, Noemí Waksman, Ricardo Gomez-Flores, Cristina Rodríguez-Padilla and Reyes Tamez-Guerra

Molbank 2006, 2006(2), M474; https://doi.org/10.3390/M474 - 10 Mar 2006

Cited by 1 | Viewed by 5797

Abstract

Synthesis of 5,5’-biindole was carried out by the Madelung indole reaction. Under strong basic conditions and high temperatures (350 ºC), N,N’-bis-formyl-o-tolidine underwent cyclization to produce high amounts of the dimeric indole. Full and unambiguous assignments of all 1H- and 13C-NMR resonances of indole [...] Read more.

Synthesis of 5,5’-biindole was carried out by the Madelung indole reaction. Under strong basic conditions and high temperatures (350 ºC), N,N’-bis-formyl-o-tolidine underwent cyclization to produce high amounts of the dimeric indole. Full and unambiguous assignments of all 1H- and 13C-NMR resonances of indole and 5,5’-biindole in DMSO-d6 are also reported. Full article

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142 KiB

Open AccessShort Note

1-ethoxycarbonylmethyl-3-(ethoxycarbonylmethylene)-2-oxo quinoxaline

by Souad Ferfra, Noureddine H. Ahabchane and El Mokhtar Essassi

Molbank 2006, 2006(2), M473; https://doi.org/10.3390/M473 - 28 Feb 2006

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Abstract

The compound 3, which exists in tautomeric equilibria between enamine (form A) and methylene imine (form B), was prepared by addition of ethoxycarbonylmethyl chloride 2 (1.23g, 0.01 mol) to a solution of 3-(ethoxycarbonylmethylene)-2-oxo quinoxaline, 1 [1] (2.32 g, 0.01 mol) in 60 [...] Read more.

The compound 3, which exists in tautomeric equilibria between enamine (form A) and methylene imine (form B), was prepared by addition of ethoxycarbonylmethyl chloride 2 (1.23g, 0.01 mol) to a solution of 3-(ethoxycarbonylmethylene)-2-oxo quinoxaline, 1 [1] (2.32 g, 0.01 mol) in 60 ml DMF, K₂CO₃ (1.38g, 0.01mol) and triethylbenzylammonium chloride (0.001 mol).[...] Full article

137 KiB

Open AccessShort Note

1-(ethoxycarbonylmethyl)-3-(1’-tolyl-3’-(ethoxycarbonyl)5’-hydroxypyrazolyl)-2-oxo quinoxaline

by Souad Ferfra, Noureddine H. Ahabchane and El Mokhtar Essassi

Molbank 2006, 2006(2), M472; https://doi.org/10.3390/M472 - 28 Feb 2006

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Abstract

To a solution of hydrazonoyl bromide (5.70 g, 0.02 mol) 2 and 1 [1] (3.18 g, 0.01 mol) in tetrahydrofuran (60 ml) was added triethylamine (2.02 g, 0.02 mol in 10 ml of THF).[...] Full article

105 KiB

Open AccessShort Note

Diethyl 2,6-Dimethyl,4-(1,1,1-trichloromethyl)-1,4-dihydropyridine-3,5-dicarboxylate

by Fatma Aydin and Recep Ozen

Molbank 2006, 2006(2), M471; https://doi.org/10.3390/M471 - 28 Feb 2006

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Abstract

In 1882, Hantzsch reported the first synthesis of dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates from a refluxing mixture of an aldehyde, a β-ketoester, and aqueous ammonium hydroxide in ethanol.[...] Full article

142 KiB

Open AccessShort Note

5,6,7,8-Tetrahydro-3-(1-methoxyiminobutyl)-1-methylsulfonylisoquinoline

by Teodozja Lipińska and Ewa Olender

Molbank 2006, 2006(2), M470; https://doi.org/10.3390/M470 - 28 Feb 2006

Viewed by 2424

Abstract

As part of research programme directed to the synthesis of novel heterocyclic compounds pharmacologically interesting [1] via ring transformation of 1,2,4-triazine derivatives, we synthesized the title compounds 3 via two step process.[...] Full article

135 KiB

Open AccessShort Note

5,6,7,8-Tetrahydro-3-(1-methoxyiminoethyl)-1-methylsulfonylisoquinoline

by Teodozja Lipińska and Beata Iwańska

Molbank 2006, 2006(2), M469; https://doi.org/10.3390/M469 - 28 Feb 2006

Viewed by 2459

Abstract

As part of research programme directed to the synthesis of novel heterocyclic compounds pharmacologically interesting [1] via ring transformation of 1,2,4-triazine derivatives, we synthesized the title compounds 3 via two step process.[...] Full article

111 KiB

Open AccessShort Note

Synthesis of 4-(4-(dimethylamino)phenyl)-5-acetyl-6-phenyl-3,4-dihydropyrimidin-2(1H)-thione

by Fatma Aydin

Molbank 2006, 2006(2), M468; https://doi.org/10.3390/M468 - 28 Feb 2006

Cited by 2 | Viewed by 2628

Abstract

4-(4-(dimethylamino)phenyl)-5-acetyl-6-phenyl-3,4-dihydropyrimidin-2(1H)-thione was prepared from benzoxyacetone (1) (1.62 g, 10 mmol), N,N-dimethylaniline (2) (1.21 g, 10 mmol) and thiourea (3) (1.140 g, 15 mmol) in dichloromethane (15 mL) as solvent using KF/Al₂O₃ (5 g) as a catalysis.[...] Full article

135 KiB

Open AccessShort Note

Synthesis of New bis-Bidentate Nitrogen Ligand: 1,4-bis[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]piperazine

by Abdeljalil El Fatmi, Maria Daoudi, Najib Ben Larbi, Abdelali Kerbal, Mohamed Filali Kaba, Brahim El Bali, Michael Bolte, Mohamed Mchich and Taibi Ben-Hadda

Molbank 2006, 2006(2), M467; https://doi.org/10.3390/M467 - 28 Feb 2006

Cited by 1 | Viewed by 4830

Abstract

The product 2 was prepared by the addition of piperazine (C₄H₁₀N₂) to 1 [1] according to the reported procedure [2].[...] Full article

116 KiB

Open AccessShort Note

Synthesis of tridentate Nitrogen Ligand : N,N-bis-(3,5-dimethylpyrazol-1-ylmethyl)benzylamine (NNNN)

by Maria Daoudi, Brahim Bennani, Assou Zahid, Mohamed Mchich and Taibi Ben Hadda

Molbank 2006, 2006(2), M466; https://doi.org/10.3390/M466 - 28 Feb 2006

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Abstract

The product 2 was prepared by the addition of benzylamine (C₆H₅CH₂NH₂) to 1 [1] according to the reported procedure [2].[...] Full article