Assessing the Impact of Non-Pharmaceutical Interventions on Consumer Mobility Patterns and COVID-19 Transmission in the US
Abstract
:1. Introduction
2. Related Work
3. Data
3.1. Non-Pharmaceutical Intervention Data
3.2. Consumer Mobility Data
3.3. COVID-19 Data
3.4. Control Variables
4. Methods
- How did early government NPIs impact individual-level consumer mobility patterns?
- How did changes in individuals’ consumer mobility patterns impact the initial spread of COVID-19 within their residing county?
4.1. Consumer Mobility Modeling
4.2. COVID-19 Modeling
5. Results
5.1. Non-Pharmaceutical Interventions
5.2. Consumer Mobility Modeling
5.3. COVID-19 Modeling
6. Discussion
7. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
CDC | Centers for Disease Control and Prevention |
WHO | World Health Organization |
NPI | Non-pharmaceutical intervention |
POS | Point-of-sale |
OxCGRT | Oxford COVID-19 Government Response Tracker |
References
- Ryan, J. Timeline of COVID-19. In Volume I: COVID-19: Global Pandemic, Societal Responses, Ideological Solutions; Routledge: Abingdon, UK, 2021; pp. xii–xxxiii. [Google Scholar]
- ACMJ. A Timeline of COVID-19 Developments in 2020. 2021. Available online: https://www.ajmc.com/view/a-timeline-of-covid19-developments-in-2020 (accessed on 15 June 2023).
- Davies, H. Unlike COVID-19, Ebola Outbreak in DRC Disproportionately Affected Children. AAP News. 2020. Available online: www.aappublications.org/news/2020/04/29/ebola042220 (accessed on 15 June 2023).
- Abbott, B.; Douglas, J. How Deadly Is COVID-19? Researchers Are Getting Closer to an Answer. Wall Str. J. 2020. Available online: www.wsj.com/articles/how-deadly-is-covid-19-researchers-are-getting-closer-to-an-answer-11595323801 (accessed on 15 June 2023).
- Pearce, K. What Is Social Distancing and How Can It Slow the Spread of COVID-19? The Hub. 2020. Available online: https://hub.jhu.edu/2020/03/13/what-is-social-distancing/ (accessed on 15 June 2023).
- Matrajt, L.; Leung, T. Evaluating the Effectiveness of Social Distancing Interventions to Delay or Flatten the Epidemic Curve of Coronavirus Disease. Emerg. Infect. Dis. 2020, 26, 1740–1748. [Google Scholar] [CrossRef] [PubMed]
- World Health Organization (WHO). Coronavirus Disease 2019 (COVID-19): Situation Report, 73. 2020. Available online: https://www.who.int/publications/m/item/situation-report—73 (accessed on 15 June 2023).
- World Health Organization (WHO). Coronavirus Disease 2019 (COVID-19): Situation Report, 72. 2020. Available online: https://www.who.int/publications/m/item/situation-report—72 (accessed on 15 June 2023).
- Bowman, A.O.; McKenzie, J.H. Managing a Pandemic at a Less Than Global Scale: Governors Take the Lead. Am. Rev. Public Adm. 2020, 50, 551–559. [Google Scholar] [CrossRef]
- Mendez-Brito, A.; El Bcheraoui, C.; Pozo-Martin, F. Systematic Review of Empirical Studies Comparing the Effectiveness of Non-Pharmaceutical Interventions Against COVID-19. J. Infect. 2021, 83, 281–293. [Google Scholar] [CrossRef] [PubMed]
- Adolph, C.; Amano, K.; Bang-Jensen, B.; Fullman, N.; Wilkerson, J. Pandemic Politics: Timing State-level Social Distancing Responses to COVID-19. J. Health Politics Policy Law 2021, 46, 211–233. [Google Scholar] [CrossRef] [PubMed]
- Chen, J.; Vullikanti, A.; Santos, J.; Venkatramanan, S.; Hoops, S.; Mortveit, H.; Lewis, B.; You, W.; Eubank, S.; Marathe, M. Epidemiological and Economic Impact of COVID-19 in the US. Sci. Rep. 2021, 11, 20451. [Google Scholar] [CrossRef] [PubMed]
- ÓhAiseadha, C.; Quinn, G.A.; Connolly, R.; Wilson, A.; Connolly, M.; Soon, W.; Hynds, P. Unintended Consequences of COVID-19 Non-Pharmaceutical Interventions (NPIs) for Population Health and Health Inequalities. Int. J. Environ. Res. Public Health 2023, 20, 5223. [Google Scholar] [CrossRef] [PubMed]
- Kraemer, M.U.; Yang, C.H.; Gutierrez, B.; Wu, C.H.; Klein, B.; Pigott, D.M.; Open COVID-19 Data Working Group; Du Plessis, L.; Faria, N.R.; Li, R.; et al. The Effect of Human Mobility and Control Measures on the COVID-19 Epidemic in China. Science 2020, 368, 493–497. [Google Scholar] [CrossRef] [PubMed]
- Zhao, S.; Zhuang, Z.; Cao, P.; Ran, J.; Gao, D.; Lou, Y.; Yang, L.; Cai, Y.; Wang, W.; He, D.; et al. Quantifying the Association Between Domestic Travel and the Exportation of Novel Coronavirus (2019-nCoV) Cases From Wuhan, China in 2020: A Correlational Analysis. J. Travel Med. 2020, 27, taaa022. [Google Scholar] [CrossRef]
- Tian, H.; Liu, Y.; Li, Y.; Wu, C.H.; Chen, B.; Kraemer, M.U.G.; Li, B.; Cai, J.; Xu, B.; Yang, Q.; et al. An Investigation of Transmission Control Measures During the First 50 days of the COVID-19 Epidemic in China. Science 2020, 368, 638–642. [Google Scholar] [CrossRef]
- Chinazzi, M.; Davis, J.T.; Ajelli, M.; Gioannini, C.; Litvinova, M.; Merler, S.; y Piontti, A.P.; Mu, K.; Rossi, L.; Sun, K.; et al. The Effect of Travel Restrictions on the Spread of the 2019 Novel Coronavirus (COVID-19) Outbreak. Science 2020, 368, 395–400. [Google Scholar] [CrossRef]
- Khan, A.; Alsofayan, Y.; Alahmari, A.; Alowais, J.; Algwizani, A.; Alserehi, H.; Assiri, A.; Jokhdar, H. COVID-19 in Saudi Arabia: The National Health Response. East. Mediterr. Health J. 2021, 27, 1114–1124. [Google Scholar] [CrossRef] [PubMed]
- AlJohani, N.I.; Mutai, K. Effect of Non-Pharmacological Interventions on the COVID-19 Epidemic in Saudi Arabia. Epidemiol. Infect. 2021, 149, e252. [Google Scholar] [CrossRef] [PubMed]
- Perez-Saez, J.; Lee, E.C.; Wada, N.I.; Alqunaibet, A.M.; Almudarra, S.S.; Alsukait, R.F.; Dong, D.; Zhang, Y.; El Saharty, S.; Herbst, C.H.; et al. Effect of Non-Pharmaceutical Interventions in the Early Phase of the COVID-19 Epidemic in Saudi Arabia. PLoS Glob. Public Health 2022, 2, e0000237. [Google Scholar] [CrossRef] [PubMed]
- Bisanzio, D.; Reithinger, R.; Alqunaibet, A.; Almudarra, S.; Alsukait, R.F.; Dong, D.; Zhang, Y.; El-Saharty, S.; Herbst, C.H. Estimating the Effect of Non-Pharmaceutical Interventions to Mitigate COVID-19 Spread in Saudi Arabia. BMC Med. 2022, 20, 51. [Google Scholar] [CrossRef] [PubMed]
- Alhomaid, A.; Alzeer, A.H.; Alsaawi, F.; Aljandal, A.; Al-Jafar, R.; Albalawi, M.; Alotaibi, D.; Alabdullatif, R.; AlGhassab, R.; Mominkhan, D.M.; et al. The Impact of Non-Pharmaceutical Interventions on the Spread of COVID-19 in Saudi Arabia: Simulation Approach. Saudi Pharm. J. 2023, 101886. [Google Scholar] [CrossRef] [PubMed]
- Zhang, X.; Warner, M.E. COVID-19 Policy Differences Across US States: Shutdowns, Reopening, and Mask Mandates. Int. J. Environ. Res. Public Health 2020, 17, 9520. [Google Scholar] [CrossRef] [PubMed]
- Siedner, M.J.; Harling, G.; Reynolds, Z.; Gilbert, R.F.; Haneuse, S.; Venkataramani, A.S.; Tsai, A.C. Social Distancing to Slow the US COVID-19 Epidemic: Longitudinal Pretest–Posttest Comparison Group Study. PLoS Med. 2020, 17, e1003376. [Google Scholar] [CrossRef]
- Abouk, R.; Heydari, B. The Immediate Effect of COVID-19 Policies on Social-Distancing Behavior in the United States. Public Health Rep. 2021, 136, 245–252. [Google Scholar] [CrossRef]
- Dave, D.; Friedson, A.I.; Matsuzawa, K.; Sabia, J.J. When Do Shelter-in-Place Orders Fight COVID-19 Best? Policy Heterogeneity Across States and Adoption Time. Econ. Inq. 2021, 59, 29–52. [Google Scholar] [CrossRef]
- Li, Y.; Li, M.; Rice, M.; Zhang, H.; Sha, D.; Li, M.; Su, Y.; Yang, C. The Impact of Policy Measures on Human Mobility, COVID-19 Cases, and Mortality in the US: A Spatiotemporal Perspective. Int. J. Environ. Res. Public Health 2021, 18, 996. [Google Scholar] [CrossRef]
- Courtemanche, C.; Garuccio, J.; Le, A.; Pinkston, J.; Yelowitz, A. Strong Social Distancing Measures In The United States Reduced The COVID-19 Growth Rate. Health Aff. 2020, 39, 1237–1246. [Google Scholar] [CrossRef] [PubMed]
- Gupta, S.; Nguyen, T.; Raman, S.; Lee, B.; Lozano-Rojas, F.; Bento, A.; Simon, K.; Wing, C. Tracking Public and Private Responses to the COVID-19 Epidemic: Evidence From State and Local Government Actions. Am. J. Health Econ. 2021, 7, 361–404. [Google Scholar] [CrossRef]
- Badr, H.S.; Du, H.; Marshall, M.; Dong, E.; Squire, M.M.; Gardner, L.M. Association Between Mobility Patterns and COVID-19 Transmission in the USA: A Mathematical Modelling Study. Lancet Infect. Dis. 2020, 20, 1247–1254. [Google Scholar] [CrossRef] [PubMed]
- Jalali, A.M.; Khoury, S.G.; See, J.; Gulsvig, A.M.; Peterson, B.M.; Gunasekera, R.S.; Buzi, G.; Wilson, J.; Galbadage, T. Delayed Interventions, Low Compliance, and Health Disparities Amplified the Early Spread of COVID-19. medRxiv 2020. [Google Scholar] [CrossRef]
- Hale, T.; Angrist, N.; Kira, B.; Petherick, A.; Phillips, T.; Webster, S. Variation in Government Responses to COVID-19; University of Oxford: Oxford, UK, 2020; Available online: www.bsg.ox.ac.uk/covidtracker (accessed on 15 June 2023).
- Data: BDEX. Available online: https://www.bdex.com/data (accessed on 1 May 2023).
- COVID-19 Response Reporting. Available online: https://www.mass.gov/info-details/covid-19-response-reporting (accessed on 1 May 2023).
- Coronavirus. Available online: https://www.michigan.gov/coronavirus/stats (accessed on 1 May 2023).
- Courtemanche, C.J.; Garuccio, J.; Le, A.; Pinkston, J.C.; Yelowitz, A. Did Social-Distancing Measures in Kentucky Help to Flatten the COVID-19 Curve? Inst. Study Free. Enterp. Work. Pap. 2020, 4. Available online: https://uknowledge.uky.edu/isfe_papers/1 (accessed on 15 June 2023).
- Chowell, G.; Sattenspiel, L.; Bansal, S.; Viboud, C. Mathematical Models to Characterize Early Epidemic Growth: A Review. Phys. Life Rev. 2016, 18, 66–97. [Google Scholar] [CrossRef] [PubMed]
- Bursztyn, L.; Rao, A.; Roth, C.P.; Yanagizawa-Drott, D.H. Misinformation During a Pandemic (No. w27417). Natl. Bur. Econ. Res. 2020. [Google Scholar] [CrossRef]
- Jiang, J.; Nguyen, T. Linear and Generalized Linear Mixed Models and Their Applications; Springer: Berlin/Heidelberg, Germany, 2007; Volume 1. [Google Scholar]
- Boubeta, M.; Lombardía, M.J.; Morales, D. Poisson Mixed Models for Studying the Poverty in Small Areas. Comput. Stat. Data Anal. 2017, 107, 32–47. [Google Scholar] [CrossRef]
- Boubeta, M.; Lombardía, M.J.; Marey-Pérez, M.; Morales, D. Poisson Mixed Models for Predicting Number of Fires. Int. J. Wildland Fire 2019, 28, 237–253. [Google Scholar] [CrossRef]
- Littell, R.C.; Pendergast, J.; Natarajan, R. Modelling Covariance Structure in the Analysis of Repeated Measures Data. Stat. Med. 2000, 19, 1793–1819. [Google Scholar] [CrossRef]
- Detry, M.A.; Ma, Y. Analyzing Repeated Measurements Using Mixed Models. JAMA 2016, 315, 407–408. [Google Scholar] [CrossRef] [PubMed]
- Wang, B.; Liu, J.; Li, Y.; Fu, S.; Xu, X.; Li, L.; Zhou, J.; Liu, X.; He, X.; Yan, J.; et al. Airborne Particulate Matter, Population Mobility and COVID-19: A Multi-City Study in China. BMC Public Health 2020, 20, 1585. [Google Scholar] [CrossRef] [PubMed]
- Brooks, M.E.; Kristensen, K.; Benthem, K.J.; Magnusson, A.; Berg, C.W.; Nielsen, A.; Skaug, H.J.; Maechler, M.; Bolker, B.M. glmmTMB Balances Speed and Flexibility Among Packages for Zero-inflated Generalized Linear Mixed Modeling. R J. 2017, 9, 378–400. [Google Scholar] [CrossRef]
- Bolker, B. Getting Started with the glmmTMB Package; R Foundation for Statistical Computing: Vienna, Austria, 2016; Available online: https://cran.r-project.org/web/packages/glmmTMB/vignettes/glmmTMB.pdf (accessed on 15 June 2023).
- R Core Team. R: A Language and Environment for Statistical Computing; R Foundation for Statistical Computing: Vienna, Austria, 2018. [Google Scholar]
- Hill, A.B. The Environment and Disease: Association or Causation? Proc. R. Soc. Med. 1965, 58, 295–300. [Google Scholar] [CrossRef]
- Fedak, K.M.; Bernal, A.; Capshaw, Z.A.; Gross, S. Applying the Bradford Hill Criteria in the 21st Century: How Data Integration has Changed Causal Inference in Molecular Epidemiology. Emerg. Themes Epidemiol. 2015, 12, 14. [Google Scholar] [CrossRef]
- Pinheiro, J.; Bates, D.; R Core Team. nlme: Linear and Nonlinear Mixed Effects Models; R Package Version 3.1-163; R Core Team: Vienna, Austria, 2023; Available online: https://CRAN.R-project.org/package=nlme (accessed on 15 June 2023).
Policy | Description | Stringency |
---|---|---|
National Emergency | On 13 March, President Trump officially declared COVID-19 a US national emergency. | 0—not effective |
1—effective | ||
Workplace Closures | A record of work closings. Workplace closures began in MA on 19 March and MI on 16 March. | 0—no measurement |
1—recommended | ||
2—required (some) | ||
3—required (all) | ||
Stay-At-Home Requirements | A record of orders requiring people to “shelter-in-place” and otherwise confine to home. Stay-at-home requirements for non-essential workers began in MA on 23 March and MI on 11 March. | 0—no measurement |
1—recommended | ||
2—required (some exceptions) | ||
3—required (minimal exceptions) | ||
Gathering Restrictions | A record of the cut-off size for bans on gatherings. Gathering restrictions began in both MA and MI on 13 March. | 0—no measurement |
1—restrict >1000 people | ||
2—restrict 101–1000 people | ||
3—restrict 11–100 people | ||
4—restrict ≤10 people |
NPI | Stringency | Days (MA) | Days (MI) |
---|---|---|---|
Workplace Closure | None | 83 (55.0%) | 75 (49.7%) |
Recommended | 0 (0.0%) | 0 (0.0%) | |
Required (some) | 0 (0.0%) | 45 (29.8%) | |
Required (all) | 68 (45.0%) | 31 (20.5%) | |
Stay-at-Home Reqs. | None | 82 (54.3%) | 70 (46.4%) |
Recommended | 69 (45.7%) | 23 (15.2%) | |
Required (some ex.) | 0 (0.0%) | 58 (38.4%) | |
Required (min ex.) | 0 (0.0%) | 0 (0.0%) | |
Gathering Restrictions | None | 72 (47.7%) | 72 (47.7%) |
Restrict >1000 | 0 (0.0%) | 0 (0.0%) | |
Restrict 101–1000 | 4 (2.7%) | 4 (2.7%) | |
Restrict 11–100 | 20 (13.2%) | 7 (4.6%) | |
Restrict <10 | 55 (36.4%) | 68 (45.0%) |
NPI (MA) | Fixed Effects | 95% CI | p-Value | NPI (MI) | Fixed Effects | 95% CI | p-Value | ||
---|---|---|---|---|---|---|---|---|---|
National Emergency | Intercept | 2.28 | (2.18,2.39) | 0.00 *** | National Emergency | Intercept | 3.18 | (3.07,3.30) | 0.00 *** |
Effective | 0.90 | (0.88,0.93) | 0.00 *** | Effective | 0.76 | (0.75,0.78) | 0.00 *** | ||
Weekend | 0.81 | (0.80,0.82) | 0.00 *** | Weekend | 0.77 | (0.77,0.78) | 0.00 *** | ||
Workplace Closure | Intercept | 2.35 | (2.24,2.45) | 0.00 *** | Workplace Closure | Intercept | 3.24 | (3.12,3.36) | 0.00 *** |
Recommended | NA | NA | NA | Recommended | NA | NA | NA | ||
Required (some) | NA | NA | NA | Required (some) | 0.86 | (0.84,0.88) | 0.00 *** | ||
Required (all) | 0.83 | (0.80,0.86) | 0.00 *** | Required (all) | 0.58 | (0.57,0.60) | 0.00 *** | ||
Weekend | 0.81 | (0.80,0.82) | 0.00 *** | Weekend | 0.77 | (0.76,0.78) | 0.00 *** | ||
Stay-at-Home Reqs. | Intercept | 2.33 | (2.23,2.44) | 0.00 *** | Stay-at-Home Reqs. | Intercept | 3.22 | (3.10,3.34) | 0.00 *** |
Recommended | 0.85 | (0.83,0.98) | 0.00 *** | Recommended | 0.93 | (0.90,0.96) | 0.00 *** | ||
Required (some ex.) | NA | NA | NA | Required (some ex.) | 0.70 | (0.68,0.71) | 0.00 *** | ||
Required (min ex.) | NA | NA | NA | Required (min ex.) | NA | NA | NA | ||
Weekend | 0.80 | (0.80,0.81) | 0.00 *** | Weekend | 0.77 | (0.76,0.78) | 0.00 *** | ||
Gathering Restrictions | Intercept | 2.31 | (2.21,2.42) | 0.00 *** | Gathering Restrictions | Intercept | 3.24 | (3.12,3.37) | 0.00 *** |
Restrict >1000 | NA | NA | NA | Restrict >1000 | NA | NA | NA | ||
Restrict 101–1000 | 1.05 | (1.00,1.11) | 0.04 * | Restrict 101–1000 | 1.14 | (1.08,1.19) | 0.00 *** | ||
Restrict 11–100 | 0.91 | (0.87,0.94) | 0.00 *** | Restrict 11–100 | 0.92 | (0.88,0.96) | 0.00 *** | ||
Restrict <10 | 0.85 | (0.83,0.88) | 0.00 *** | Restrict <10 | 0.70 | (0.69,0.72) | 0.00 *** | ||
Weekend | 0.81 | (0.80,0.82) | 0.00 *** | Weekend | 0.77 | (0.76,0.78) | 0.00 *** |
Lag Period | Fixed Effects | 95% CI | p-Value | |
---|---|---|---|---|
08 Days | Intercept | 20.40 | (6.48,34.33) | 0.00 *** |
Transactions | 0.18 | (−0.09,0.44) | 0.19 | |
Test Rate | −0.09 | (−0.16,−0.01) | 0.02 ** | |
Weekend | −28.38 | (−41.73,−15.03) | 0.00 *** | |
10 Days | Intercept | 20.03 | (6.60,33.46) | 0.00 *** |
Transactions | 0.18 | (−0.08,0.45) | 0.18 | |
Test Rate | −0.08 | (−0.15,0.00) | 0.04 ** | |
Weekend | −30.27 | (−43.73,−16.82) | 0.00 *** | |
12 Days | Intercept | 18.04 | (6.85,29.23) | 0.00 *** |
Transactions | 0.32 | (0.08,0.57) | 0.01 ** | |
Test Rate | −0.05 | (−0.13,0.02) | 0.14 | |
Weekend | −26.14 | (−39.23,−13.04) | 0.00 *** | |
14 Days | Intercept | 20.40 | (6.48,34.33) | 0.00 *** |
Transactions | 0.18 | (−0.09,0.44) | 0.19 | |
Test Rate | −0.09 | (−0.16,−0.01) | 0.02 ** | |
Weekend | −28.38 | (−41.73,−15.03) | 0.00 *** |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Zuccarelli, J.; Seaman, L.; Rader, K. Assessing the Impact of Non-Pharmaceutical Interventions on Consumer Mobility Patterns and COVID-19 Transmission in the US. Int. J. Environ. Res. Public Health 2024, 21, 67. https://doi.org/10.3390/ijerph21010067
Zuccarelli J, Seaman L, Rader K. Assessing the Impact of Non-Pharmaceutical Interventions on Consumer Mobility Patterns and COVID-19 Transmission in the US. International Journal of Environmental Research and Public Health. 2024; 21(1):67. https://doi.org/10.3390/ijerph21010067
Chicago/Turabian StyleZuccarelli, Joseph, Laura Seaman, and Kevin Rader. 2024. "Assessing the Impact of Non-Pharmaceutical Interventions on Consumer Mobility Patterns and COVID-19 Transmission in the US" International Journal of Environmental Research and Public Health 21, no. 1: 67. https://doi.org/10.3390/ijerph21010067
APA StyleZuccarelli, J., Seaman, L., & Rader, K. (2024). Assessing the Impact of Non-Pharmaceutical Interventions on Consumer Mobility Patterns and COVID-19 Transmission in the US. International Journal of Environmental Research and Public Health, 21(1), 67. https://doi.org/10.3390/ijerph21010067