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Current Oncology
Volume 14
Issue 5
10.3747/co.2007.149
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Article

Canadian Supportive Care Recommendations for the Management of Anemia in Patients with Cancer

by
J. Mikhael
1,*,
B. Melosky
2,
C. Cripps
3,
D. Rayson
4 and
C. T. Kouroukis
5
1
Princess Margaret Hospital, 610 University Avenue, 5-125, Toronto, ON M5G 2M9, Canada
2
BC Cancer Agency, Vancouver, BC, Canada
3
Ottawa Hospital Regional Cancer Centre, Ottawa, ON, Canada
4
QEII Health Sciences Centre, Halifax, NS, Canada
5
The Juravinski Cancer Centre, Hamilton, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2007, 14(5), 209-217; https://doi.org/10.3747/co.2007.149
Submission received: 5 July 2007 / Revised: 5 August 2007 / Accepted: 5 September 2007 / Published: 1 October 2007

Abstract

Anemia is a common finding in cancer patients, most often as a result of chemotherapy. Management of anemia requires a comprehensive approach of appropriate diagnosis, exclusion of reversible causes, use of erythropoiesis-stimulating agents (esas), and iron supplementation. Recently, consensus guidelines on the management of chemotherapy-induced anemia were published in Europe and the United States. The present review is intended to be a practical guide for Canadian physicians, based on published guidelines, but specifically tailored to the Canadian environment. Recommendations for the use of esas are presented, including initiation, target hemoglobin, dosing and adjustments, monitoring, and re-initiation. Issues of safety are also addressed, including thromboembolic risk, impact on survival, and tumour progression. The importance of iron metabolism and the use of iron supplementation (both oral and parenteral) is discussed.
Keywords: Canadian recommendations; anemia; cancer; supportive care; erythropoiesis-stimulating agent; esa; chemotherapy-induced anemia; cia; iron; safety Canadian recommendations; anemia; cancer; supportive care; erythropoiesis-stimulating agent; esa; chemotherapy-induced anemia; cia; iron; safety

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MDPI and ACS Style

Mikhael, J.; Melosky, B.; Cripps, C.; Rayson, D.; Kouroukis, C.T. Canadian Supportive Care Recommendations for the Management of Anemia in Patients with Cancer. Curr. Oncol. 2007, 14, 209-217. https://doi.org/10.3747/co.2007.149

AMA Style

Mikhael J, Melosky B, Cripps C, Rayson D, Kouroukis CT. Canadian Supportive Care Recommendations for the Management of Anemia in Patients with Cancer. Current Oncology. 2007; 14(5):209-217. https://doi.org/10.3747/co.2007.149

Chicago/Turabian Style

Mikhael, J., B. Melosky, C. Cripps, D. Rayson, and C. T. Kouroukis. 2007. "Canadian Supportive Care Recommendations for the Management of Anemia in Patients with Cancer" Current Oncology 14, no. 5: 209-217. https://doi.org/10.3747/co.2007.149

APA Style

Mikhael, J., Melosky, B., Cripps, C., Rayson, D., & Kouroukis, C. T. (2007). Canadian Supportive Care Recommendations for the Management of Anemia in Patients with Cancer. Current Oncology, 14(5), 209-217. https://doi.org/10.3747/co.2007.149

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