Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry

Jamal, S.; Sheppard, A.J.; Cotterchio, M.; Gallinger, S.

doi:10.3747/co.27.6039

Open AccessArticle

Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry

by

S. Jamal

^1,*,

A.J. Sheppard

^1,2,

M. Cotterchio

^1,2 and

S. Gallinger

^3,4

¹

Ontario Health (Cancer Care Ontario), Toronto, ON, Canada

²

Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

³

Lunenfeld–Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada

⁴

Department of Surgery, University Health Network, Toronto, ON, Canada

^*

Author to whom correspondence should be addressed.

Curr. Oncol. 2020, 27(4), 395-398; https://doi.org/10.3747/co.27.6039

Submission received: 6 May 2020 / Revised: 3 June 2020 / Accepted: 7 July 2020 / Published: 1 August 2020

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Abstract

Introduction: Colorectal cancer is one of the most common cancers in Ontario and imposes a high burden on many Indigenous populations. There are two aims for this short communication: (1) Highlight colorectal risk factor findings from a population-based case–control study; (2) Highlight trends and challenges of colorectal cancer research in Indigenous populations in Ontario. Methods: Prevalences of cigarette smoking, obesity, fruit and vegetable consumption, and family history of colorectal cancer were estimated using the Indigenous identifier in the Ontario Familial Colon Cancer Registry for 1999–2007 and then compared for cases and controls using age-adjusted odds ratios (ORs) with 95% confidence intervals (CIs). Results: The registry search identified 66 Indigenous cases and 23 Indigenous controls. Cigarette smoking (OR: 1.88; 95% CI: 0.63 to 5.60) and obesity (OR: 2.16; 95% CI: 0.72 to 6.46) were higher in cases, but not statistically significantly so. Conclusions: Findings were consistent with previous literature describing Indigenous populations. A small sample size and poor Indigenous identification questions make it challenging to comprehensively understand cancer risk factors and burden in Indigenous populations.

Keywords: indigenous health; cancer prevention

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MDPI and ACS Style

Jamal, S.; Sheppard, A.J.; Cotterchio, M.; Gallinger, S. Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry. Curr. Oncol. 2020, 27, 395-398. https://doi.org/10.3747/co.27.6039

AMA Style

Jamal S, Sheppard AJ, Cotterchio M, Gallinger S. Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry. Current Oncology. 2020; 27(4):395-398. https://doi.org/10.3747/co.27.6039

Chicago/Turabian Style

Jamal, S., A.J. Sheppard, M. Cotterchio, and S. Gallinger. 2020. "Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry" Current Oncology 27, no. 4: 395-398. https://doi.org/10.3747/co.27.6039

APA Style

Jamal, S., Sheppard, A. J., Cotterchio, M., & Gallinger, S. (2020). Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry. Current Oncology, 27(4), 395-398. https://doi.org/10.3747/co.27.6039

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Association between Known Risk Factors and Colorectal Cancer Risk in Indigenous People Participating in the Ontario Familial Colon Cancer Registry

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