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Correction to Viruses 2022, 14(9), 1938.
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Correction

Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938

by
Shouzhi Yu
1,†,
Yangyang Wei
1,†,
Hongyang Liang
1,†,
Wenheng Ji
1,
Zhen Chang
1,
Siman Xie
1,
Yichuan Wang
1,
Wanli Li
1,
Yingwei Liu
1,
Hao Wu
1,
Jie Li
1,
Hui Wang
1,* and
Xiaoming Yang
2,*
1
Beijing Institute of Biological Products Company Limited, Beijing 100176, China
2
China National Biotec Group Company Limited, Beijing 100024, China
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Viruses 2023, 15(5), 1035; https://doi.org/10.3390/v15051035
Submission received: 11 April 2023 / Accepted: 17 April 2023 / Published: 23 April 2023
(This article belongs to the Collection Coronaviruses)
Versions Notes

Error in Table 3

In the original publication [1], there was a mistake in Table 3. ELISA analysis of protein and antigen concentrations of different inactivated virus samples as published. In the table, data in the second column (protein concentration) and the third column (antigen concentration) are raw data, and data in the fourth column were calculated from data in the third column divided by data in the second column. In the original publication, data in the fourth column were wrongly entered in. The corrected Table 3 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Text Correction

With regard to the correction of Table 3, a correction has been made to *4. Discussion, Paragraph 4*:
**The results showed that formaldehyde treatment reduced the homogeneity of virus particles. Although there were no significant differences in the negative staining or circular dichroism spectra, the treament’s performance in terms of size exclusion chromatography became worse, and its UV absorption curve became less sharp. An examination of the S protein showed that the viral S protein after formaldehyde treatment displayed dispersive bands and cross-linking upon SDS-PAGE. Compared with the 20–24 h BPL treatment, the S antigen content decreased by more than twice. After BPL treatment, the virus particles remained relatively homogenous, and the S protein was still clear. These results confirm the chemical properties of formaldehyde, which can cause viral protein cross-linking and denaturation and damage viral surface antigens. Therefore, although formaldehyde does not destroy the morphology or secondary structure of the virus, compared with BPL, formaldehyde is not a suitable SARS-CoV-2 inactivator.**

Reference

  1. Yu, S.; Wei, Y.; Liang, H.; Ji, W.; Chang, Z.; Xie, S.; Wang, Y.; Li, W.; Liu, Y.; Wu, H.; et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938. [Google Scholar] [CrossRef] [PubMed]
Table
Table 3. ELISA analysis of protein and antigen concentrations of different inactivated virus samples.
Table 3. ELISA analysis of protein and antigen concentrations of different inactivated virus samples.
SampleProtein Concentration (μg/mL)Antigen Concentration (U/mL)Ratio
(U/μg)
Formaldehyde-inactivated332.4267.90.81
Formaldehyde + BPL-inactivated211.33224.571.06
BPL-inactivated327.56623.381.90
BPL + BPL-inactivated308.19372.561.21
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MDPI and ACS Style

Yu, S.; Wei, Y.; Liang, H.; Ji, W.; Chang, Z.; Xie, S.; Wang, Y.; Li, W.; Liu, Y.; Wu, H.; et al. Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938. Viruses 2023, 15, 1035. https://doi.org/10.3390/v15051035

AMA Style

Yu S, Wei Y, Liang H, Ji W, Chang Z, Xie S, Wang Y, Li W, Liu Y, Wu H, et al. Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938. Viruses. 2023; 15(5):1035. https://doi.org/10.3390/v15051035

Chicago/Turabian Style

Yu, Shouzhi, Yangyang Wei, Hongyang Liang, Wenheng Ji, Zhen Chang, Siman Xie, Yichuan Wang, Wanli Li, Yingwei Liu, Hao Wu, and et al. 2023. "Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938" Viruses 15, no. 5: 1035. https://doi.org/10.3390/v15051035

APA Style

Yu, S., Wei, Y., Liang, H., Ji, W., Chang, Z., Xie, S., Wang, Y., Li, W., Liu, Y., Wu, H., Li, J., Wang, H., & Yang, X. (2023). Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938. Viruses, 15(5), 1035. https://doi.org/10.3390/v15051035

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