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Article

Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor

by
Zahra Arab
1,
Sara Jafarian
1,*,
Hassan Karimi-Maleh
2,*,
Leila Roozbeh Nasiraie
1 and
Mohammad Ahmadi
3
1
Food Science Department, Nour Branch, Islamic Azad University, Nour 4641859557, Iran
2
Department of Chemical Engineering, Quchan University of Technology, Quchan 9477177870, Iran
3
Food Science & Technology Department, Ayatollah Amoli Branch, Islamic Azad University, Amol 4615143358, Iran
*
Authors to whom correspondence should be addressed.
Sustainability 2022, 14(4), 2169; https://doi.org/10.3390/su14042169
Submission received: 19 November 2021 / Revised: 3 February 2022 / Accepted: 6 February 2022 / Published: 14 February 2022
(This article belongs to the Special Issue Food Processing, Characterization, Treatment, and Conversion of Waste to Value)
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Versions Notes

Abstract

:
A high performance and fast response sensor was fabricated as a monitoring system for the determination of butylated hydroxyanisole (BHA) in food and wastewater samples. In this regard, a carbon paste electrode (CPE) that was amplified with platinum-decorated single wall carbon nanotubes (Pt/SWCNTs) and 1-Butyl-3-methylimidazolium chloride ([C4mim][Cl]) was investigated as a new electroanalytical sensor for the monitoring of BHA in aqueous solution. The [C4mim][Cl]/Pt/SWCNTs/CPE offered an excellent catalytic activity on oxidation signal of BHA and enhanced its oxidation current about 5.51 times. In the final step, the standard addition results confirmed the powerful ability of [C4mim][Cl]/Pt/SWCNTs/CPE to the monitoring of BHA in different water and food samples with acceptable recovery data.

1. Introduction

The monitoring of food compounds is one of the major steps in the investigation of food quality [1,2]. There are several ingredients in food products that should be studied before use by customers. For many years, due to the close relationship between food quality and human health, measuring and evaluating food quality has been one of the priorities of global organizations [3]. Here, sensors show a significant role in this field, as they gather relevant information from the quality and safety of food products. These data help to create smart food. On the other hand, many of the biomass-derived materials are highly recommended for the fabrication of electro-analytical tools due to their unique features such as sustainability, regenerative nature, and cost-effectiveness [4]. Therefore, sensors and especially electrochemical sensors are a new approach in analytical systems to achieve sustainability goals. Among food additives, antioxidants have been considered more than other additives due to their many benefits and key roles in improving food quality [5]. Tert-butyl-4-methoxyphenol or butylated hydroxyanisole (C11H16O2) is one of the more commonly used antioxidant food additives that are permitted for application in approximately 50 countries [6]. According to the US Food and Drug Administration reported data, the presence of 0.02% w/w of BHA in the total value food produces is safe and cannot create any problems for human health in low concentrations. However, the National Toxicological Program (NTP) report showed that a high dose of BHA is harmful and can cause cancer. Therefore, controlling the amount of BHA in the food production process is important [7].
Accordingly, measurement methods have been used for many years as a suitable strategy to evaluate the quality of food products [8]. Various measurement methods such as chromatography, spectroscopy, and electrochemical sensors have been proposed to monitor food composition [9,10,11,12,13]. Electrochemical methods have received greater attention than the other techniques [14,15]. Butylated hydroxyanisole is a common antioxidant and is added to edible fats and fat-containing foods [6]. Research studies confirm that high doses of BHA in food products can be hazardous for the human body and the monitoring of its concentration is important in food products. Therefore, some analytical methods such as electrochemical sensors [16], fluorimetry [17], gas-liquid chromatography [18], capillary electrophoresis [19], and high performance liquid chromatograpy (HPLC) [20] were suggested for the electrochemical determination of BHA concentrations.
Electrochemical sensors are one of the biggest branches of sensor tools that create a relationship between electrical signals and the concentration of compounds [21,22,23,24,25]. Electrochemical sensors have many benefits in monitoring biological and food products such as fast response, low cost, easy operation, portability, and easy modification compared to other analytical systems [26,27,28,29]. Electrochemical sensors can be easily modified to create sensitive and selective analytical instruments for monitoring systems [30,31,32]. Recently, electrochemical methods have gained a special place in food and pharmaceutical analysis as an alternative to most measurement methods [31,33,34,35]. The unique features of electrochemical sensors, such as fast measurement speed and the ability to become portable kits, have led most large companies to accept this technique as a suitable strategy [36,37]. The behavior of electrochemical sensors is relative to the modification process [38,39,40]. In this regard, nanomaterials and ionic liquids have been widely used to modify electrodes [41,42].
Nanomaterials are powerful and strategic materials with unique properties and are useful for different branches of science [43,44,45,46,47,48,49,50,51,52,53]. Due to the unique properties of nanomaterials, extensive research has been conducted on the application of nanomaterials in various sciences such as the food industry, pharmaceutical industry, water-treatment measurement sensors, mechanical engineering, and energy industries [54,55,56,57,58,59,60,61]. Platinum-based nanomaterials have shown high-performance catalytic activity in electrochemical systems [62].
Ionic liquids are a group of organic materials with unique properties and high electrical conductivity that have been widely used in the synthesis of chemicals and the catalysis of various chemical reactions as well as electrochemical sensors [63,64]. In recent years, they have been employed as a suitable alternative to paraffin in the manufacture of carbon paste electrodes due to their superior electrical conductivity [64,65]. According to the literature, [C4mim][Cl] is a good conductive mediator for the modification of paste electrodes and is the suitable choice for the fabrication of highly sensitive electrochemical sensors [66].
Based on the explanations that are provided in the previous paragraphs, nanomaterials and ionic liquids have been used as suitable modifiers for electrochemical sensors. Numerous scientific reports have shown that the simultaneous use of these modifiers can create unique features for electrochemical sensors.
In this research work, a new and powerful electroanalytical sensor ([C4mim][Cl]/Pt/SWCNTs/CPE) was fabricated for monitoring BHA as an antioxidant food additive. The results showed the powerful ability of [C4mim][Cl]/Pt/SWCNTs/CPE for trace level analysis of BHA in food samples. The [C4mim][Cl]/Pt/SWCNTs/CPE can be monitored BHA in low concentrations with a detection limit of 0.5 nM, which is the equivalent to (and in many cases better than) the previously described electrochemical sensors.

2. Experimental Section

2.1. Materials

Butylated hydroxyanisole (99.0%), sodium hydroxide (99.0%), and phosphoric acid (85.0%) were purchased from Alfa Aesar Company. 1,2-hexadecanediol (90.0%), Pt(acac)2, SWCNTs, graphite powder < 150 μm (99%), 1-butyl-3-methylimidazolium chloride, hexane (≥90%), and ethanol (99%) were purchased from Sigma-Aldrich Company. The phosphate buffer solution (PBS 0.1 M) was prepared using phosphate salts such as NaH2PO4, Na2HPO4, Na3PO4.
Pt/SWCNTs was synthesized by the reported procedure in our previously published paper by polyol strategy [62].

2.2. Fabrication of Sensor

The ratio of graphite powder to Pt/SWCNTs nanocomposite and also the ratio of [C4mim][Cl] to paraffin oil (as binders) in the fabrication of [C4mim][Cl]/Pt/SWCNTs/CPE were optimized in the presence of BHA. After optimization, the [C4mim][Cl]/Pt/SWCNTs/CPE was prepared by mixing 0.94 g graphite powder + 0.06 gr Pt/SWCNTs in a mortar and pestle in the presence 10 mL ethanol as a solvent. After evaporation of the ethanol in 40 ◦C, the suitable amount of paraffin oil and [C4mim][Cl] (8:2 v:v) were added drop wise as binders in a mortar and pestle and hand mixed for 60 min. The obtained paste was transferred into a glass tube with a diameter of 3.0 mm and connected with Ivium-Vertex as a working electrode by a copper wire. Before recording of any signal, [C4mim][Cl]/Pt/SWCNTs/CPE was polished by white paper.

2.3. Instruments

Electrochemical signals were recorded by an electrochemical machine Ivium-Vertex (Netherlands). The recording systems were connected to an Ag/AgCl/KClsat, Pt wire, and [C4mim][Cl]/Pt/SWCNTs/CPE as the reference, counter, and working electrode, respectively. Transmission electron microscope (TEM) model Zeiss-EM10C-100 KV (Germany) was used for morphological investigation.

2.4. Real Sample Preparation

Edible oil, orange juice, and wastewater were selected for real sample analysis. The orange juice and wastewater were centrifuged (3000 rpm) and filtered. Afterwards, 5 mL of the filtered juice or wastewater sample was mixed with phosphate buffer solution (0.1 M pH = 7.0) and used for real sample analysis. The edible oil was prepared by mixing 2 mL of the sample and 20 mL hexane in an erlenmeyer flask, followed by centrifugation at 3200 rpm for 10 min. Following that, 10 mL hexane was added to the sample, and the mixture was shaken for 45 min in the same conditions. In the final step, 2 mL of the extracted sample was dissolved by 2 mL pure ethanol and the sample was mixed with phosphate buffer solution and transferred into an electrochemical cell for real sample analysis.

2.5. Electrochemical Measurement of [C4mim][Cl]/Pt/SWCNTs/CPE

The [C4mim][Cl]/Pt/SWCNTs/CPE was polished with white paper. The BHA (0.01 m) solution was prepared by dissolving 0.018 g BHA into 10.0 mL of the buffer solution (PBS, 0.1 M, pH 7.0). The SW voltammograms were recorded in the potential range −0.20 and +0.75 V vs. Ag/AgCl with a frequency 10 HZ. Linear sweep voltammograms were acquired from the solution containing 700 µM BHA in the potential range −0.3–650 mV. The plot of net-current vs. concentration was used for the calibration curve plot.

3. Results

3.1. Charactrization of Modified Electrode

The electrochemical impedance spectroscopic (EIS) method was employed for the characterization of modified and unmodified sensors in the presence of BHA (not shown). The charge transfer resistance (Rct) was detected about 2.70 KΩ, 1.8 KΩ, 1.3 KΩ, and 0.7 KΩ at the surface of CPE, Pt/SWCNTs/CPE, [C4mim][Cl]/CPE, and [C4mim][Cl]/Pt/SWCNTs/CPE, respectively. The moving from 2.7 KΩ to 0.8 KΩ from CPE to [C4mim][Cl]/Pt/SWCNTs/CPE confirmed the high electrical conductivity of [C4mim][Cl] and Pt/SWCNTs as two new electro-catalysts.

3.2. pH Investigation

The oxidation signal of BHA was recorded in different pH ranges at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE using the square wave voltametric method. The results were depicted in the inset of Figure 1. Using oxidation peak potentials, a linear relationship was observed between the oxidation potential of BHA and pH with an equation of E = 0.0603 pH + 0.7177 (R2 = 0.9987) that confirmed a pH-dependent reaction according to Scheme 1 for redox reaction of BHA in aqueous solutions (Figure 1). As can be seen, with an increasing pH value, the value of protons in the solution was reduced and the redox process was performed more easily and shifted the potential to lower values.
On the other hand, the maximum oxidation signal for redox reaction of BHA was observed on pH = 7.0 and this condition was used for the next steps (Figure 2).

3.3. Modification Effect

The SW voltammograms of BHA were recorded at the surface of the amplified and unmodified electrodes. BHA offered the oxidation currents of 5.66 µA, 13.0 µA, 20.4 µA, and 31.2 µA with the oxidation potentials of 439 mV, 310 mV, 312 mV, and 285 mV at surface of CPE (curve a), Pt/SWCNTs/CPE (curve b), [C4mim][Cl]/CPE (curve c), and [C4mim][Cl]/Pt/SWCNTs/CPE (curve d), respectively. When comparing the oxidation current and oxidation potential at the surface of CPE with [C4mim][Cl]/Pt/SWCNTs/CPE confirmed an improvement in the current of about 5.51 times and a reduction in the oxidation potential of about 185 mV (Figure 3). These improvements were ascribed to the addition of the conductive mediators ([C4mim][Cl] and Pt/SWCNTs in this case) at the surface of CPE. Replacing [C4mim][Cl] with paraffin oil and Pt/SWCNTs nanocomposite with carbon powder in the sensor greatly increased the electrical conductivity of the electrode surface, creating a sensor with good electrical conductivity. This catalytic property can make it possible to monitor a low concentration of BHA.

3.4. Scan Rate Study and Stability Invesigation

The linear sweep voltammograms (LSV) of 700 µM BHA were recorded in the scan rate range 50–300 mV/s (Figure 4 inset). The linear relationship between the oxidation current of BHA and ν1/2 with an equation of I = 3.3609 ν1/2 −14.6670 (R2 = 0.9979) in the scan rate range 50–300 mV/s, suggested a diffusion process for redox reaction of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE (Figure 4).
The stability of [C4mim][Cl]/Pt/SWCNTs/CPE for monitoring of 240 µM BHA was checked over a period of 95 days. The results confirmed that 90% of the initial signal of BHA remained at the end of the period of three months at surface of the new sensor, confirming the high stability of [C4mim][Cl]/Pt/SWCNTs/CPE in monitoring (see Figure 5). The RSD% value for 11 successive assays of BHA was about 1.1% using [C4mim][Cl]/Pt/SWCNTs/CPE as a sensor. The seven [C4mim][Cl]/Pt/SWCNTs/CPEs were fabricated in the same condition and used for monitoring of 240 µM BHA at pH = 7.0. The RSD% was determined about 2.6%. This point confirmed the good reproducibility of [C4mim][Cl]/Pt/SWCNTs/CPE for the monitoring of BHA.

3.5. Analytical Investigation

The application of [C4mim][Cl]/Pt/SWCNTs/CPE for the determination of BHA was checked in this step by the square wave voltammetric (SWV) method (Figure 6). The results showed that the oxidation signal of BHA had a linear relationship with its concentration with the equation of I = 0.1209 C + 2.2790 (R2 = 0.9966) in the range of 1.0–300 µM. On the other hand, the sensor showed a detection limit (LOD = 3 Sb/m) of 0.5 nM and LOQ of 1.5 nM for the monitoring of BHA at the optimum conditions. These LDR and LOD values for [C4mim][Cl]/Pt/SWCNTs/CPE monitoring of BHA were comparable to, and in some cases, were better than the prior recommended sensors (see Table 1).

3.6. Selectivity Investigation

In this stage, the selectivity of [C4mim][Cl]/Pt/SWCNTs/CPE for monitoring 10 M BHA was investigated in the presence of certain food and inorganic substances. The results were displayed in Table 2 with an acceptable error rate of 5% in current. As can be seen, the [C4mim][Cl]/Pt/SWCNTs/CPE showed a good selectivity for the monitoring of BHA in an aqueous solution.

3.7. Real Sample Analysis

The capability of [C4mim][Cl]/Pt/SWCNTs/CPE for the monitoring of BHA in the real samples was checked by the standard addition methods. For this propose, edible oil and orange juice were selected and prepared according to reported procedure in Section 2. The results were tabulated in Table 3, and the recovery range of 98.25–104.3% confirmed the capability of [C4mim][Cl]/Pt/SWCNTs/CPE as new analytical tool for the monitoring of BHA in real samples.

4. Conclusions

A novel, powerful, and fast analytical sensor was fabricated for the monitoring of BHA in the aqueous solutions. In this regard, CPE was amplified with [C4mim][Cl] and Pt/SWCNTs and employed for electrochemical determination of BHA in the concentration range of 1.0–300 µM. The [C4mim][Cl]/Pt/SWCNTs/CPE showed a high catalytic activity on the oxidation signal of BHA and improved the redox reaction of this antioxidant under optimum conditions. In the final step, [C4mim][Cl]/Pt/SWCNTs/CPE was successfully used for the monitoring BHA in different food and wastewater samples with acceptable recovery data.

Author Contributions

Methodology, L.R.N.; formal analysis, Z.A.; writing—original draft preparation, H.K.-M.; writing—review and editing, M.A.; supervision and project administration, S.J. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Mustafa, F.; Andreescu, S. Chemical and biological sensors for food-quality monitoring and smart packaging. Foods 2018, 7, 168. [Google Scholar] [CrossRef] [Green Version]
  2. Kuswandi, B.; Wicaksono, Y.; Abdullah, A.; Heng, L.Y.; Ahmad, M. Smart packaging: Sensors for monitoring of food quality and safety. Sens. Instrum. Food Qual. Saf. 2011, 5, 137–146. [Google Scholar] [CrossRef]
  3. Wang, N.; Zhang, N.; Wang, M. Wireless sensors in agriculture and food industry—Recent development and future perspective. Comput. Electron. Agric. 2006, 50, 1–14. [Google Scholar] [CrossRef]
  4. Benny, L.; John, A.; Varghese, A.; Hegde, G.; George, L. Waste elimination to porous carbonaceous materials for the application of electrochemical sensors: Recent developments. J. Clean. Prod. 2021, 290, 125759. [Google Scholar] [CrossRef]
  5. Tinggi, U. Selenium: Its role as antioxidant in human health. Environ. Health Prev. Med. 2008, 13, 102–108. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  6. Verhagen, H.; Schilderman, P.A.; Kleinjans, J.C. Butylated hydroxyanisole in perspective. Chem. Biol. Interact. 1991, 80, 109–134. [Google Scholar] [CrossRef]
  7. Leslie, S.W.; Gad, S.C.; Acosta, D. Cytotoxicity of butylated hydroxytoluene and butylated hydroxyanisole in cultured heart cells. Toxicology 1978, 10, 281–289. [Google Scholar] [CrossRef]
  8. Mustafa, F.; Andreescu, S. Nanotechnology-based approaches for food sensing and packaging applications. RSC Adv. 2020, 10, 19309–19336. [Google Scholar] [CrossRef]
  9. Boyce, M.C. Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in food by mixed micellar electrokinetic chromatography. J. Chromatogr. A 1999, 847, 369–375. [Google Scholar] [CrossRef]
  10. Cozzolino, D. Infrared spectroscopy as a versatile analytical tool for the quantitative determination of antioxidants in agricultural products, foods and plants. Antioxidants 2015, 4, 482–497. [Google Scholar] [CrossRef]
  11. Alizadeh, M.; Mehmandoust, M.; Nodrat, O.; Salmanpour, S.; Erk, N. A glassy carbon electrode modified based on molybdenum disulfide for determination of folic acid in the real samples. J. Food Meas. Charact. 2021, 15, 5622–5629. [Google Scholar] [CrossRef]
  12. Mehmandoust, M.; Erk, N.; Alizadeh, M.; Salmanpour, S. Voltammetric carbon nanotubes based sensor for determination of tryptophan in the milk sample. J. Food Meas. Charact. 2021, 15, 5288–5295. [Google Scholar] [CrossRef]
  13. Tajik, S.; Orooji, Y.; Karimi, F.; Ghazanfari, Z.; Beitollahi, H.; Shokouhimehr, M.; Varma, R.S.; Jang, H.W. High performance of screen-printed graphite electrode modified with Ni–Mo-MOF for voltammetric determination of amaranth. J. Food Meas. Charact. 2021, 15, 4617–4622. [Google Scholar] [CrossRef]
  14. Fu, L.; Chen, F.; Zhao, S.; Yu, J.; Karimi-Maleh, H.; Lin, C.-T. Analysis of coumarin in food and plant tissue without extraction based on voltammetry of microparticles. J. Food Meas. Charact. 2021, 15, 5439–5444. [Google Scholar] [CrossRef]
  15. Zabihpour, T.; Shahidi, S.-A.; Karimi-Maleh, H.; Ghorbani-HasanSaraei, A. Voltammetric food analytical sensor for determining vanillin based on amplified NiFe 2 O 4 nanoparticle/ionic liquid sensor. J. Food Meas. Charact. 2020, 14, 1039–1045. [Google Scholar] [CrossRef]
  16. Karimi, F.; Bijad, M.; Farsi, M.; Vahid, A.; Asari-Bami, H.; Wen, Y.; Ganjali, M.R. A new nanostructure square wave voltammetric platform for determination of tert-butylhydroxyanisole in food samples. Curr. Anal. Chem. 2019, 15, 172–176. [Google Scholar] [CrossRef]
  17. Hurtubise, R.; Latz, H.W. Fluorimetric determination of butylated hydroxy anisole in food products and packaging material. J. Agric. Food Chem. 1970, 18, 377–380. [Google Scholar] [CrossRef] [PubMed]
  18. Buttery, R.; Stuckey, B. Food Antioxidants, Determination of Butylated Hydroxyanisole and Butylated Hydroxytoluene in Potato Granules by Gas-Liquid Chromatography. J. Agric. Food Chem. 1961, 9, 283–285. [Google Scholar] [CrossRef]
  19. Xiang, Q.; Gao, Y.; Xu, Y.; Wang, E. Capillary electrophoresis-amperometric determination of antioxidant propyl gallate and butylated hydroxyanisole in foods. Anal. Sci. 2007, 23, 713–717. [Google Scholar] [CrossRef] [Green Version]
  20. Yankah, V.V.; Ushio, H.; Ohshima, T.; Koizumi, C. Quantitative determination of butylated hydroxyanisole, butylated hydroxytoluene, and tert-butyl hydroquinone in oils, foods, and biological fluids by high-performance liquid chromatography with fluorometric detection. Lipids 1998, 33, 1139–1145. [Google Scholar] [CrossRef]
  21. Mehmandoust, M.; Erk, N.; Karaman, C.; Karimi, F.; Salmanpour, S. Sensitive and selective electrochemical detection of epirubicin as anticancer drug based on nickel ferrite decorated with gold nanoparticles. Micromachines 2021, 12, 1334. [Google Scholar] [CrossRef]
  22. Mehmandoust, M.; Erk, N.; Karaman, C.; Karaman, O. An electrochemical molecularly imprinted sensor based on CuBi2O4/rGO@ MoS2 nanocomposite and its utilization for highly selective and sensitive for linagliptin assay. Chemosphere 2021, 291, 132807. [Google Scholar] [CrossRef]
  23. Senturk, H.; Eksin, E.; Zeybek, U.; Erdem, A. Detection of Senecionine in Dietary Sources by Single-Use Electrochemical Sensor. Micromachines 2021, 12, 1585. [Google Scholar] [CrossRef] [PubMed]
  24. Fu, L.; Zheng, Y.; Zhang, P.; Lai, G. Quantification of silicon in rice based on an electrochemical sensor via an amplified electrocatalytic strategy. Micromachines 2021, 12, 1048. [Google Scholar] [CrossRef]
  25. Moghadam, F.H.; Taher, M.A.; Agheli, H. Electroanalytical Monitoring of Glutathione in Biological Fluids Using Novel Pt/SWCNTs-Ionic Liquid Amplified Sensor. Top. Catal. 2022. [Google Scholar] [CrossRef]
  26. Yang, R.; Fan, B.; Wang, S.a.; Li, L.; Li, Y.; Li, S.; Zheng, Y.; Fu, L.; Lin, C.-T. Electrochemical Voltammogram Recording for Identifying Varieties of Ornamental Plants. Micromachines 2020, 11, 967. [Google Scholar] [CrossRef] [PubMed]
  27. Low, S.S.; Ji, D.; Chai, W.S.; Liu, J.; Khoo, K.S.; Salmanpour, S.; Karimi, F.; Deepanraj, B.; Show, P.L. Recent Progress in Nanomaterials Modified Electrochemical Biosensors for the Detection of MicroRNA. Micromachines 2021, 12, 1409. [Google Scholar] [CrossRef] [PubMed]
  28. Zhao, L. Horseradish Peroxidase Labelled-Sandwich Electrochemical Sensor Based on Ionic Liquid-Gold Nanoparticles for Lactobacillus brevis. Micromachines 2021, 12, 75. [Google Scholar] [CrossRef]
  29. Sohrabi, H.; Majidi, M.R.; Arbabzadeh, O.; Khaaki, P.; Pourmohammad, S.; Khataee, A.; Orooji, Y. Recent advances in the highly sensitive determination of zearalenone residues in water and environmental resources with electrochemical biosensors. Environ. Res. 2022, 204, 112082. [Google Scholar] [CrossRef] [PubMed]
  30. Salmanpour, S.; Abbasghorbani, M.; Karimi, F.; Bavandpour, R.; Wen, Y. Electrocatalytic determination of cysteamine uses a nanostructure based electrochemical sensor in pharmaceutical samples. Curr. Anal. Chem. 2017, 13, 40–45. [Google Scholar] [CrossRef]
  31. John, A.; Benny, L.; Cherian, A.R.; Narahari, S.Y.; Varghese, A.; Hegde, G. Electrochemical sensors using conducting polymer/noble metal nanoparticle nanocomposites for the detection of various analytes: A review. J. Nanostruct. Chem. 2021, 11, 1–31. [Google Scholar] [CrossRef]
  32. Mehmandoust, M.; Çakar, S.; Özacar, M.; Salmanpour, S.; Erk, N. Electrochemical sensor for facile and highly selective determination of antineoplastic agent in real samples using glassy carbon electrode modified by 2D-MoS2 NFs/TiO2 NPs. Top. Catal. 2021. [Google Scholar] [CrossRef]
  33. Karimi-Maleh, H.; Karimi, F.; Fu, L.; Sanati, A.L.; Alizadeh, M.; Karaman, C.; Orooji, Y. Cyanazine herbicide monitoring as a hazardous substance by a DNA nanostructure biosensor. J. Hazard. Mater. 2022, 423, 127058. [Google Scholar] [CrossRef] [PubMed]
  34. Alizadeh, M.; Azar, P.A.; Mozaffari, S.A.; Karimi-Maleh, H.; Tamaddon, A.-M. A DNA based biosensor amplified with ZIF-8/ionic liquid composite for determination of mitoxantrone anticancer drug: An experimental/docking investigation. Front. Chem. 2020, 8, 814. [Google Scholar] [CrossRef]
  35. Koshki, M.-S.; Baghayeri, M.; Fayazi, M. Application of sepiolite/FeS2 nanocomposite for highly selective detection of mercury (II) based on stripping voltammetric analysis. J. Food Meas. Charact. 2021, 15, 5318–5325. [Google Scholar] [CrossRef]
  36. Moghaddam, A.; Zamani, H.A.; Karimi-Maleh, H. A New Electrochemical Platform for Dasatinib Anticancer Drug Sensing Using Fe3O4-SWCNTs/Ionic Liquid Paste Sensor. Micromachines 2021, 12, 437. [Google Scholar] [CrossRef]
  37. Salmanpour, S.; Karimi, F.; Khalilzadeh, M.A.; Gupta, V.K.; Keyvanfard, M.; Bagheri, H. Liquid phase determination of isuprel in pharmaceutical and biological samples using a nanostructure modified carbon paste electrode. J. Mol. Liq. 2015, 201, 108–112. [Google Scholar] [CrossRef]
  38. Karimi-Maleh, H.; Khataee, A.; Karimi, F.; Baghayeri, M.; Fu, L.; Rouhi, J.; Karaman, C.; Karaman, O.; Boukherroub, R. A green and sensitive guanine-based DNA biosensor for idarubicin anticancer monitoring in biological samples: A simple and fast strategy for control of health quality in chemotherapy procedure confirmed by docking investigation. Chemosphere 2021, 291, 132928. [Google Scholar] [CrossRef]
  39. Gupta, V.K.; Karimi-Maleh, H.; Sadegh, R. Simultaneous determination of hydroxylamine, phenol and sulfite in water and waste water samples using a voltammetric nanosensor. Int. J. Electrochem. Sci. 2015, 10, 303–316. [Google Scholar]
  40. Fouladgar, M. CuO-CNT nanocomposite/ionic liquid modified sensor as new breast anticancer approach for determination of doxorubicin and 5-fluorouracil drugs. J. Electrochem. Soc. 2018, 165, B559. [Google Scholar] [CrossRef]
  41. Moshirian-Farahi, S.S.; Zamani, H.A.; Abedi, M. Nano-molar level determination of isoprenaline in pharmaceutical and clinical samples; A nanostructure electroanalytical strategy. Eurasian Chem. Commun. 2020, 2, 702–711. [Google Scholar] [CrossRef] [Green Version]
  42. Hussain, R.T.; Islam, A.S.; Khairuddean, M.; Suah, F.B.M. A polypyrrole/GO/ZnO nanocomposite modified pencil graphite electrode for the determination of andrographolide in aqueous samples. Alex. Eng. J. 2021, 61, 4209–4218. [Google Scholar]
  43. Deeksha, B.; Sadanand, V.; Hariram, N.; Rajulu, V. Preparation and properties of cellulose nanocomposite fabrics with in situ generated silver nanoparticles by bioreduction method. J. Bioresour. Bioprod. 2021, 6, 75–81. [Google Scholar]
  44. Cheng, Z.; Meng, J.; Wang, X. Preparation of wood-based filter loaded with Ag nanoparticles and its catalytic degradation performance on organic dye. J. For. Eng. 2020, 5, 94–98. [Google Scholar]
  45. Pyrzynska, K.; Sentkowska, A. Biosynthesis of selenium nanoparticles using plant extracts. J. Nanostruct. Chem. 2021. [Google Scholar] [CrossRef]
  46. Nangare, S.N.; Patil, S.R.; Patil, A.G.; Khan, Z.G.; Deshmukh, P.K.; Tade, R.S.; Mahajan, M.R.; Bari, S.B.; Patil, P.O. Structural design of nanosize-metal–organic framework-based sensors for detection of organophosphorus pesticides in food and water samples: Current challenges and future prospects. J. Nanostruct. Chem. 2021. [Google Scholar] [CrossRef]
  47. Xia, H.; Jiahuan, A.N.; Zhang, W.; GE, C.; Zuo, S. Effect of the metal-support interaction on catalytic oxidation performances of HMF on Ag nanoparticles. J. For. Eng. 2020, 5, 88–93. [Google Scholar]
  48. Muhammad, T.; Waqas, H.; Manzoor, U.; Farooq, U.; Rizvi, Z.F. On doubly stratified bioconvective transport of Jeffrey nanofluid with gyrotactic motile microorganisms. Alex. Eng. J. 2022, 61, 1571–1583. [Google Scholar] [CrossRef]
  49. Bai, S.; Han, C.; Ni, Z.; Ni, Y.; Lyu, Y.; Ye, X. Effect of polyethylene glycol(PEG)on properties of the surface modified cellulose nanofiber(CNF)/polylactic acid(PLA)composite. J. For. Eng. 2020, 5, 62–68. [Google Scholar]
  50. Rajabi, M.; Moradi, O.; Mazlomifar, A. Adsorption of methyl orange dye from water solutions by carboxylate group functionalized multi-walled carbon nanotubes. Int. J. Nano Dimens. 2015, 6, 227–240. [Google Scholar]
  51. Zhang, Y.; Wei, L.; Lu, L.; Gan, L.; Pan, M. Adsorption-photocatalytic properties of cellulose nanocrystal supported ZnO nanocomposites. J. For. Eng. 2020, 5, 29–35. [Google Scholar]
  52. Keyikoglu, R.; Khataee, A.; Lin, H.; Orooji, Y. Vanadium (V)-doped ZnFe LDH for enhanced sonocatalytic degradation of pymetrozine. Chem. Eng. J. 2022, 434, 134730. [Google Scholar] [CrossRef]
  53. Taherian, Z.; Gharahshiran, V.S.; Khataee, A.; Orooji, Y. Synergistic effect of freeze-drying and promoters on the catalytic performance of Ni/MgAl layered double hydroxide. Fuel 2021, 311, 122620. [Google Scholar] [CrossRef]
  54. Miao, X.; Lin, J.; Bian, F. Utilization of discarded crop straw to produce cellulose nanofibrils and their assemblies. J. Bioresour. Bioprod. 2020, 5, 26–36. [Google Scholar] [CrossRef]
  55. Korkmaz, S.; Kariper, İ.A.; Karaman, O.; Karaman, C. The production of rGO/RuO2 aerogel supercapacitor and analysis of its electrochemical performances. Ceram. Int. 2021, 47, 34514–34520. [Google Scholar] [CrossRef]
  56. Yorseng, K.; Siengchin, S.; Ashok, B.; Rajulu, A.V. Nanocomposite Egg Shell Powder with in situ Generated Silver Nanoparticles Using Inherent Collagen as Reducing Agent. J. Bioresour. Bioprod. 2020, 5, 101–107. [Google Scholar] [CrossRef]
  57. Babu, A.M.; Rajeev, R.; Thadathil, D.A.; Varghese, A.; Hegde, G. Surface modulation and structural engineering of graphitic carbon nitride for electrochemical sensing applications. J. Nanostruct. Chem. 2021. [Google Scholar] [CrossRef]
  58. Karaman, C. Orange Peel Derived-Nitrogen and Sulfur Co-doped Carbon Dots: A Nano-booster for Enhancing ORR Electrocatalytic Performance of 3D Graphene Networks. Electroanalysis 2021, 33, 1356–1369. [Google Scholar] [CrossRef]
  59. Akça, A.; Karaman, O.; Karaman, C. Mechanistic insights into catalytic reduction of N2O by CO over Cu-embedded graphene: A density functional theory perspective. ECS J. Solid State Sci. Technol. 2021, 10, 041003. [Google Scholar] [CrossRef]
  60. Arefi-Oskoui, S.; Khataee, A.; Behrouz, S.J.; Vatanpour, V.; Gharamaleki, S.H.; Orooji, Y.; Safarpour, M. Development of MoS2/O-MWCNTs/PES blended membrane for efficient removal of dyes, antibiotic, and protein. Sep. Purif. Technol. 2022, 280, 119822. [Google Scholar] [CrossRef]
  61. Taherian, Z.; Khataee, A.; Han, N.; Orooji, Y. Hydrogen production through methane reforming processes using promoted-Ni/mesoporous silica: A review. J. Ind. Eng. Chem. 2021. [Google Scholar] [CrossRef]
  62. Karimi-Maleh, H.; Alizadeh, M.; Orooji, Y.; Karimi, F.; Baghayeri, M.; Rouhi, J.; Tajik, S.; Beitollahi, H.; Agarwal, S.; Gupta, V.K. Guanine-based DNA biosensor amplified with Pt/SWCNTs nanocomposite as analytical tool for nanomolar determination of daunorubicin as an anticancer drug: A docking/experimental investigation. Ind. Eng. Chem. Res. 2021, 60, 816–823. [Google Scholar] [CrossRef]
  63. Bijad, M.; Karimi-Maleh, H.; Farsi, M.; Shahidi, S.-A. An electrochemical-amplified-platform based on the nanostructure voltammetric sensor for the determination of carmoisine in the presence of tartrazine in dried fruit and soft drink samples. J. Food Meas. Charact. 2018, 12, 634–640. [Google Scholar] [CrossRef]
  64. Opallo, M.; Lesniewski, A. A review on electrodes modified with ionic liquids. J. Electroanal. Chem. 2011, 656, 2–16. [Google Scholar] [CrossRef]
  65. Wei, D.; Ivaska, A. Applications of ionic liquids in electrochemical sensors. Anal. Chim. Acta 2008, 607, 126–135. [Google Scholar] [CrossRef]
  66. Zabihpour, T.; Shahidi, S.-A.; Karimi Maleh, H.; Ghorbani-HasanSaraei, A. MnFe2O4/1-Butyl-3-methylimidazolium hexafluorophosphate modified carbon paste electrode: An amplified food sensor for determination of gallic acid in the presence of ferulic acid as two phenolic antioxidants. Eurasian Chem. Commun. 2020, 2, 362–373. [Google Scholar]
  67. Thomas, D.; Rasheed, Z.; Jagan, J.S.; Kumar, K.G. Study of kinetic parameters and development of a voltammetric sensor for the determination of butylated hydroxyanisole (BHA) in oil samples. J. Food Sci. Technol. 2015, 52, 6719–6726. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  68. Rasheed, Z.; Vikraman, A.E.; Thomas, D.; Jagan, J.S.; Kumar, K.G. Carbon-nanotube-based sensor for the determination of butylated hydroxyanisole in food samples. Food Anal. Methods 2015, 8, 213–221. [Google Scholar] [CrossRef]
  69. Jayasri, D.; Narayanan, S.S. Manganese (II) hexacyanoferrate based renewable amperometric sensor for the determination of butylated hydroxyanisole in food products. Food Chem. 2007, 101, 607–614. [Google Scholar] [CrossRef]
  70. Manoranjitham, J.J.; Narayanan, S.S. Electrochemical sensor for determination of butylated hydroxyanisole (BHA) in food products using poly O-cresolphthalein complexone coated multiwalled carbon nanotubes electrode. Food Chem. 2021, 342, 128246. [Google Scholar] [CrossRef]
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Figure 1. Potential-pH curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE. (Inset). Relative SW voltammograms.
Figure 1. Potential-pH curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE. (Inset). Relative SW voltammograms.
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Scheme 1. Redox mechanism of BHA.
Scheme 1. Redox mechanism of BHA.
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Figure 2. Current-pH curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE.
Figure 2. Current-pH curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE.
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Figure 3. SW voltammograms of BHA at the surface of CPE (a), Pt/SWCNTs/CPE (b), [C4mim][Cl]/CPE (c), and [C4mim][Cl]/Pt/SWCNTs/CPE (d), respectively.
Figure 3. SW voltammograms of BHA at the surface of CPE (a), Pt/SWCNTs/CPE (b), [C4mim][Cl]/CPE (c), and [C4mim][Cl]/Pt/SWCNTs/CPE (d), respectively.
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Figure 4. Current −ν1/2 curve for electro-oxidation of 700 µM BHA. (Inset) LS voltammograms 700 µM BHA at scan rates (a) 50; (b) 90; (c) 140; and (d) 300 mV/s.
Figure 4. Current −ν1/2 curve for electro-oxidation of 700 µM BHA. (Inset) LS voltammograms 700 µM BHA at scan rates (a) 50; (b) 90; (c) 140; and (d) 300 mV/s.
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Figure 5. Stability diagram of BHA at surface of [C4mim][Cl]/Pt/SWCNTs/CPE (n = 4.0).
Figure 5. Stability diagram of BHA at surface of [C4mim][Cl]/Pt/SWCNTs/CPE (n = 4.0).
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Figure 6. Current-concentration curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE (n = 4.0). (Inset). The relative SW voltammograms in the range of 1.0–300 µM.
Figure 6. Current-concentration curve for electro-oxidation of BHA at the surface of [C4mim][Cl]/Pt/SWCNTs/CPE (n = 4.0). (Inset). The relative SW voltammograms in the range of 1.0–300 µM.
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Table
Table 1. Comparing the sensing ability of [C4mim][Cl]/Pt/SWCNTs/CPE with previously reported sensors for the monitoring of BHA.
Table 1. Comparing the sensing ability of [C4mim][Cl]/Pt/SWCNTs/CPE with previously reported sensors for the monitoring of BHA.
ElectrodeMediatorLOD (µM)LDR (µM)Ref.
Glassy carbon electrodePoly L−cysteine0.11.0–10.0[67]
PlatinumMultiwalled carbon nanotube0.0940.1–1.0[68]
GraphiteManganese (II) hexacyanoferate0.050.49–142[69]
Paraffin wax impregnated graphiteO-cresolphthalein complexone (OC) over the multiwalled carbon nanotubes0.110.33–110[70]
Carbon paste[C4mim][Cl]/Pt/SWCNTs0.00050.001–300This work
Table
Table 2. Selectivity of [C4mim][Cl]/Pt/SWCNTs/CPE for the monitoring of BHA.
Table 2. Selectivity of [C4mim][Cl]/Pt/SWCNTs/CPE for the monitoring of BHA.
SpeciesTolerance Limits (WSubstance/WBHA)
glucose, citric acid, and fructose400
Starchsaturation
SCN−, Br−, Ca2+, K+, Na+1000
glycine, lucine, phenylalanine500
Table
Table 3. Real sample analysis of BHA using [C4mim][Cl]/Pt/SWCNTs/CPE.
Table 3. Real sample analysis of BHA using [C4mim][Cl]/Pt/SWCNTs/CPE.
SampleBHA Added (µM)BHA Expected (µM)BHA Founded (µM)Recovery%
Orange juice------<LOD---
10.0010.0010.43 ± 0.87104.3
Edible oil------<LOD---
20.0020.0019.65 ± 0.9898.25
Wastewater------<LOD---
15.0015.0015.63 ± 0.79104.2
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Arab, Z.; Jafarian, S.; Karimi-Maleh, H.; Roozbeh Nasiraie, L.; Ahmadi, M. Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor. Sustainability 2022, 14, 2169. https://doi.org/10.3390/su14042169

AMA Style

Arab Z, Jafarian S, Karimi-Maleh H, Roozbeh Nasiraie L, Ahmadi M. Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor. Sustainability. 2022; 14(4):2169. https://doi.org/10.3390/su14042169

Chicago/Turabian Style

Arab, Zahra, Sara Jafarian, Hassan Karimi-Maleh, Leila Roozbeh Nasiraie, and Mohammad Ahmadi. 2022. "Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor" Sustainability 14, no. 4: 2169. https://doi.org/10.3390/su14042169

APA Style

Arab, Z., Jafarian, S., Karimi-Maleh, H., Roozbeh Nasiraie, L., & Ahmadi, M. (2022). Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor. Sustainability, 14(4), 2169. https://doi.org/10.3390/su14042169

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