Milk Formula Enriched with Sodium Butyrate Influences Small Intestine Contractility in Neonatal Pigs
, Stefan Grzegorz Pierzynowski 2,3,4, Paulina Szczurek 5, Kateryna Pierzynowska 4,6,*, Piotr Wychowański 7, Blanka Seklecka 8, Maciej Koperski 1, Anna Starzyńska 9, Dominika Szkopek 10, Janine Donaldson 3,11, Krzysztof Andrzejewski 12 and Jarosław Woliński 6,10,*
Round 1
Reviewer 1 Report
This manuscript describes a well conducted and clearly presented study. experimental methodology is sound and data is clearly presented and appropriately interpreted. Findings of the study will make important contribution to the field.
Author Response
We would like to thank for the evaluation of our work and recommendations directed to improve the presented material. We have revised the manuscript and the edited version has been submitted together with the response to your comments. We hope you will find them acceptable.
Reviewer 2 Report
Abstract
“Ach” “TTX” “EFS” unknown abbreviated words are exist.
What is “dietary butyrate”
The methods were lacked in the abstract.
Introduction was well described.
What is the evidence for the dosage of butyric acid?
Is there any need to evaluate butyric acid for adverse events?
Is there any difference in absorption between butyric acid in human milk and butyric acid in reagents?
Figure. The place of figure legends is inappropriate.
Line 213: Please insert a space before “the”.
Is it unnecessary to identify the intervening molecules to elucidate the effects of butyric acid on sympathetic and parasympathetic nerves? Is it acting directly? If there is some intervening molecule, then it may be useful to examine it using an inhibitor.
Author Response
Please see the attachment
